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Furthermore, abnormal morphology, shrinkage and reduced density of dendritic spines and defects in LTP were observed in brains of the patients suffering from mental retardation and neurodegenerative diseases; many mutant genes found from these patients encode component proteins of signal transduction for neuronal plasticity. These studies on synaptic plasticity would certainly promote making the effective prevention and treatment procedures for mental and neurodegenerative diseases.

此外,在精神迟滞性疾病和神经退行性疾病患者脑内记录到异常的LTP,并发现神经元的树突棘数量减少,形态上产生畸变或萎缩,同时发现,产生突变的基因大多编码调节突触可塑性的信号通路蛋白,故突触可塑性研究也将促进精神和神经疾病的预防和治疗。

Identification of two mutations in CTNS, the only gene known to be associated with cystinosis, is confirmatory.

CTNS基因是唯一已知的与胱氨酸病相关的基因,CTNS基因的两个突变的鉴定是被证实的。

Most cases of FOP arise as a result of a spontaneous new mutation, and so this is very likely to be your sister's case since you do not repeort anyone else in your family that has FOP.

FOP大多数病例往往会发展成一个新的自发突变的结果,所以这很可能是你妹妹的情况(对不起,我在这里向Robert博士介绍说Tingting是我的妹妹),因为你没有告知你家里其他人FOP的状况。

Abrupt fluid contacts indicate a permeable reservoir;gradational ones indicate a low permeability with a high capillary pressure.

突变的流体界面表层储层具有很好的渗透率,而渐变的流体界面表明储层的渗透率较差,且储层的毛细压力较高。

Since the Km〓 gene of pCS4 and pCS11 was derived from the mesophile plasmid pUB110 and coded for a thermolabile protain, it conferred Km〓 phenotype on the host cell at 48℃ only. Mutant Km〓 gene was obtained by selecting for Km〓 phenotype at elevated growth temperature. In this way improved vectors pCS5 and pCS12 were obtained, which can be used at 65℃ by Km selection.

利用提高培养温度后选择卡那霉素抗性表型的方法,从编码不耐热蛋白质的卡那霉素抗性基因出发,得到了提高其耐热性的突变的卡那霉素抗性基因,从而改造了CS4和pCS11,得到了适用温度达65℃的改进的载体质粒pCS5和pCS12。

It is caused by a mutation in the genes that dictate the way our bodies produce skin.

这是所造成的突变的在基因支配的方式我们的身体产生的皮肤。

In the new view, viz. Neo-Darwinism theory, product family development system is analyzed and the architecture of product family gene model is built. After analyzing the gene expression of product family model, the center-principle for product family gene model is proposed and its information hereditary mechanisms are clarified. The algorithms of transcription, retrotranscription, translation, direct-translation and mutation for information gene are presented.

从一个新的角度——现代达尔文主义学说对产品族设计系统进行了分析,在此基础上,建立了产品族基因建模体系结构,分析了产品族模型的基因表达,提出了产品族基因建模中心法则,并对其中各个信息遗传机制进行了详细的分析和论述,给出了相应的信息基因转录、逆转录、基因转译、基因直译以及基因突变的算法。

Methods: In order to study P〓、P〓 and bcl-2 gene expression and its significance in tumorgenesis of lung cancer, the expression of P〓、P〓 and bcl-2 gene was detected by RT-PCR, PCR-SSCP and immunhistochemistry SABC in 65 cases of lung cancer tissues, tissues adjacent to carcinoma and normal tissues, its correlation to clinico-pathological features and prognosis of lung cancer was explored.

因此人们预测其重要性不亚于RB和P〓基因,甚至比其更为重要。Bcl-2基因是继促进细胞生长的癌基因和突变的抑癌基因之后,近年来发现的第三类肿瘤基因,它是一种调控细胞死亡的"存活基因",可抑制细胞的程序化死亡,故称之为细胞凋亡抑制基因,在肿瘤发生、发展中起着重要的作用。

However, indisputable that the flu virus mutation rate is very fast, every quarter of the viral gene version and the last quarter of the infected people there are small differences.

但毋庸质疑的是,流感病毒突变的速度非常之快,每一季的病毒基因版本都和上一季人们所感染到的有微小差别。

According to molecular mechanism of gene mutation, no matter what transvertion or transition happens, several replications are needed.

根据基因突变的分子机制,无论是碱基的转换或颠换,都需经过几次的复制,即经过几个世代才能完或,这也是在后期世代才出现高油酸变异的原因。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。