突变的

Injection of wild-type or mutated agrin into rat soleus muscle induced the formation of nonsynaptic acetylcholine receptor clusters, but the mutant protein specifically destabilized the endogenous neuromuscular junctions.

注射野生型或突变型集聚蛋白到大鼠比目鱼肌中，诱导非突触性乙酰胆碱受体簇的形成，但突变的蛋白破坏了内源性神经肌肉接头的稳定性。

A malignant transformant line 3T3 (T24) was obtained by transfection of mouse fibroblast NIH3T3 cells with pMAMneo-T24-ras plasmid. 3T3 (T24) cells were cultured continuously in the presence of benzamide , an NAD site inhibitor of poly polymerase .

将12位密码子突变的活化ras癌基因全cDNA序列克隆到真核表达载体pSV2neo和pMAMneo上，获得了相应的重组质粒pSV2neo-T24-ras和pMAMneo-T24-ras，将pMAMneo-T24-ras质粒利用基因转移方法导入小鼠成纤维细胞NIH3T3中，活化的ras癌基因可使受体细胞发生恶性转化。

Accession Number: AF151005.Conclusion A single-copy fragment containing cis-acting "CACA" box has been identified, which might be the upstream of a new tumor suppressor gene deleted in tumors of the stomach and small intestine.

在胃、小肠肿瘤组织发生缺失突变的片段可能为某一抑癌基因的前半部分，即含有启动子成分的调控元件部分CACA盒。

BCR-ABL and mutant JAK2 inhibit the Bcl-x deamidation pathway and the apoptotic response to DNA damage in primary cells from patients with CML or polycythemia vera.

BCR-ABL和突变的JAK2可抑制CML或真性红细胞增多症患者Bcl -×的脱酰胺途径和原代细胞DNA损伤诱导的凋亡反应。

"Other chips have been developed to assess drug metabolism," said Jorge Bezerra, MD, a pediatric gastroenterologist at Cincinnati Children's and the study's lead investigator."This is the first chip in the world that has been customized to diagnose genetic mutations in patients with inherited types of liver diseases."

&其他芯片开发用于评价药物代谢，& Cincinnati儿童医院的儿童胃肠病学家、该研究的首席研究员，Jorge Bezerra博士说：&这是世界上第一种制定并用于诊断遗传型肝脏疾病患者遗传突变的芯片。&

However, use of this chicken feed across the board for other animals, like pigs and sheep, increase the contamination and creates mutative qualities that put the public at risk.

然而，如果养鸡饲料的使用扩展到其他动物，比如猪和羊，那么这种污染的扩大和产生突变的可能将会危及到公众。

Then they examined PTEN in nonhereditary breast tumors from 297 patients and tumors from 34 women who had inherited the BRCA1 mutation.

研究人员检查了297例非遗传性乳腺癌患者肿瘤中PTEN基因，同时也检查了34例具有BRCA1突变的遗传性乳腺癌中的PTEN基因的情况。

Ten years after diagnosis, 13.6% of the women with a genetic mutation had experienced a recurrence similar to previously found rates for women with nonhereditary cancers treated with BCT.

在明确诊断后的10年，13.6％有基因突变的女性出现肿瘤复发，与以前使用BCT治疗的非遗传性乳腺癌女性相似。

Amplification of n sequence by PCR can be used to detect HD gene presymptomatically and prenatally in HD families and to discriminate clinical cases with untypical features from HD.

应用PCR技术直接检测动态突变的重复序列，可为这些疾病的临床诊断和鉴别诊断提供有力的依据。

Matthews GV, Bartholomeusz A, Locarnini S, Ayres A, Sasaduesz J, Seaberg E, Cooper DA, Lewin S, Dore GJ, Thio CL.

随着治疗持续时间的延长，这种突变的流行率增加，治疗4年以上的患者达到94%。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。