突变型

The above data indicated that abrogation of X-ray-induced G2/M arrest by Tet was associated with p53 function.

结果说明突变型p53细胞对Tet诱导的G2期阻滞的清除作用比野生型p53细胞更敏感。

The effect of CPI-deficiency on the photophysical and photochemical characteristics of the mutant alga were studied in detail.

本文首先详细地研究了CPI的部分缺失对突变型衣藻的光物理和光化学反应的影响。

The effect of the CPI-deficiency on the photophysical and photochemical characterization of the mutant alga was further studied.

进而详细地研究了CPI的部分缺失对突变型衣藻的光物理和光化学反应的影响。

METHODS摘要: Molecular cloning techniques were used to construct the recombinant plasmid pLMP1p53mt containing mutant p53 gene and EB virus LMP1 gene. Linear recombinant plasmid pLMP1p53mt was transfected into mouse androgenesis of germ cells by microinjection and then survival germ cells treated were planted into fallopian tubes of artificial pregnant female mice.

方法摘要：通过分子克隆技术构建含突变型p53基因和EB病毒LMP1基因的真核表达载体pLMP1p53mt；采用显微注射法将线性化的表达载体注射至小鼠受精卵的雄性原核中，然后将注射存活的受精卵植入假孕母鼠的输卵管；取其产3 wk龄子代鼠进行PCR初选，再通过Southern杂交进一步确证；利用HE染色法观察4 mo龄转基因小鼠不同组织病理变化。

Methods The amino modified wild-type and mutant probes of 16 loci ˇ1888, 3200, 3206, 3243, 3290, 3316, 3394, 3593, 3426, 12026, 12258, 14577, 14693, 14709, 16189, 16223ˇ in mitochondrial genome were immobilized onto the activated slides with aldehyde surface using Biochip Arrayer, then they were incubated overnight in a humid chamber at room temperature.

方法将氨基修饰的16个常见易感基因位点ˇ1888ˇ3200ˇ3206ˇ3243ˇ3290ˇ3316ˇ3394ˇ3593ˇ3426ˇ12026ˇ12258ˇ14577，14693ˇ14709ˇ16189ˇ16223ˇ的野生型和突变型探针ˇ通过Packard芯片点样仪点样于醛基修饰的基片上ˇ室温保湿过夜固定。

In our study,42 isolates were tested,in which 22 isolates were found to be resistant to chloroquine and the others were susceptible.

结果42个样本中，pfmdr1第86位氨基酸均未发生突变，即86位氨基酸是野生型的Asn，而不是突变型的Tyr。

Methods: The expression of mutated P53 gene in human lymphocytes was investigated using flow cytometry.And the micronucleus and sister chromatid exchange tests were studied in vitro.

以正常人外周血淋巴细胞为材料，用流式细胞仪检测环磷酰胺对突变型P53基因表达的影响，同时以微核及姐妹染色单体互换为指标，进行致突变研究。

In scc-3 mutant animals, normal SCs were not visible and ～24 DAPI-staining positive structures were seen in diakinesis, indicating that SCC-3 is necessary for the establishment or maintenance of sister-chromatid cohesion.

在scc-3突变型线虫细胞中，无法观察到正常的联会复合体，且在终变期出现大约24个DAPI染色阳性信号。

Objective To study the expression of survivin and its relationship with the expressions of p53 and bcl-2 in gastric adenocarcinoma and dysplasia.

目的 探讨凋亡抑制基因Survivin在胃癌、胃黏膜异型增生组织中的表达及其与突变型p53、bcl-2的相关性。

One year later, Slit was confirmed as the ligand of Robo and the Slit-Robo signaling is know involved in the repulsive effect of the commission axons crossing the mid-line, and also involved in the repulsive effect of the guidance of neuronal migration and leukocyte migration as well.

而对 Slit 功能展开的研究起于1998年，先是发现其受体 Robo突变型果蝇的中线处交叉神经元的导向发生缺陷。1999年的一系列遗传和生化的研究又发现，分泌性因子 Slit 正是 Robo 的配体， Slit － Robo 信号起到了排斥一些轴突，使之无法穿过中线的作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。