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穿心莲内酯

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ObjectiveTo study the acute toxicity of andrographolide derivatives.

目的研究穿心莲内酯衍生物的急性毒性。

Objective: Solid dispersion technique was used for enhancing the dissolution rate of Andrographolide.

应用固体分散体技术,以提高穿心莲内酯的体外溶出速率。

Objective To compare the difference in bioavailability of microemulsion and pill by detecting the concentration of andrographolide in rabbit plasma.

目的 通过检测给药后家兔血浆中穿心莲内酯的含量,比较微乳制剂与片剂的生物利用度的差异。

RESULTS: Tea polyphenols, orindonin, baicalin and andrographolide had obvious inhibition effect on colorectal cancer cell lines.

结果:冬凌草甲素、茶多酚、穿心莲内酯和黄芩苷对Lovo细胞和SW480细胞有明显的抑制作用。

[Objective] To determine the sensitivity of Andrographolide in gastric cancer cell lines in various degrees of differentiation.

内容摘要:作者:董建华叶再元李曙光陶厚权杨琼[目的]明确穿心莲内酯对不同分化胃癌细胞株的体外增殖的影响。

Results The solubility of andrographolide in aqueous solution was very low, and was higher in the oil phase. The andrographolide was highly fat-soluble drugs.

结果 穿心莲内酯在水相中的溶解度非常低,在油相中的溶解度较高,属于脂溶性很强的药物。

[Objective] To determine the sensitivity of Andrographolide in gastric cancer cell lines in various degrees of differentiation.

作者:董建华叶再元李曙光陶厚权杨琼[目的]明确穿心莲内酯对不同分化胃癌细胞株的体外增殖的影响。

RESULTS: Tea polyphenols, orindonin, baicalin and andrographolide had obvious inhibition effects on colorectal cancer cell lines.

结果: 冬凌草甲素、茶多酚、穿心莲内酯和黄芩苷对Lovo细胞和SW480细胞有明显的抑制作用。

Andrographolide droppill is effective and safe in the treatment of acute upper respiratory tract infection with external windheat syndrome.

本研究于2002年4月至2006年9月,分两个阶段对穿心莲内酯滴丸治疗急性上呼吸道感染外感风热证的有效性和安全性进行评价。

Aim: To investigate the effects of andrographolide on activation, proliferation and cell-cycle, to elucidate the mechanism of the immunosuppressive effect of andrographolide.

目的:研究穿心莲内酯对小鼠T淋巴细胞体外活化、增殖及细胞周期的影响,并对其免疫调节作用进行初步探讨。

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