空泡组织

In pathological examination, the range of vacuolation and the inflammatory reaction were more lightly than that in Group B, and the number of normal neurocyte was higher than that in Group B.

组织病理学检查发现A组于脊髓再灌注后各时相点脊髓神经细胞空泡变性范围、炎症反应明显轻于B组，脊髓前角正常神经元计数均显著高于B组

Hepatopancreas are damaged worst, which are full of empty vesicles and amylaceous materials, devoid of any recognizable cellular structures.

肝胰腺组织损伤最为严重，超微结构显示为大量空泡结构和淀粉样物质，已无可识别的细胞结构。

Granule- and vacuole-like cells were observed in liver of ICP rats under light microscope and Bile canaliculi were dilated and deposition of substances with high electronic density was found in bile canaliculi and hepatocytes of ICP rats by electronic microscopy.

胆淤组孕鼠肝脏光镜下见部分肝细胞有颗粒样变性和空泡变性，电镜下见肝组织中毛细胆管扩张，毛细胆管及肝细胞内见高电子致密物沉积。

PartⅡ:Effect of bicyclol on hepatocyte apoptosis in alcohol-intoxicated mice and related mechanismsThree consecutive intragastric administration of alcohol(6g/kg)in 12h interval resulted in an obvious liver injury and inflammation in mice,as indicated by the elevation of serum alanine transaminase(2.2 fold of control),increased hepatic COX-2 protein expression(2.2 fold of control),as well as liver pathological changes characterized by myelonic degeneration,vacuolar degeneration and inflammatory infiltration.

双环醇对酒精中毒小鼠肝脏细胞凋亡的保护作用及机制研究小鼠连续三次酒精(6g/kg)灌胃后可导致明显肝损伤，变现为血清ALT水平升高(为对照组的2.2倍)，肝脏炎症相关蛋白环氧合酶-2(cyclooxygenase-2，COX-2)表达增加(为对照组的2.2倍)，肝组织出现髓样变性、小空泡变性和炎性细胞浸润。

ResultsCompared with group A and group C, significant increase in the levels of IL 8 and MDA and decrease in the activities of SOD and GSH Px were noted in group B （F=5.86-18.41,q＝3.15-7.17, P.01）; compared with group A, the activity of SOD and GSH Px was not changed markedly, the levels of IL 8 and MDA rised slightly but with no statistically significant. Mitochondria became vacuolated and deformed in group B, slightly swollen in group C.

结果 与A组、C组相比较，B组SOD、GSH Px的活性显著下降，MDA含量、IL 8浓度显著上升(F=5.86～18.41，q＝3.15～7.17，P.01)；与A组比较，C组SOD、GSH Px活性无明显变化，MDA含量及IL 8浓度轻微上升，但无统计学差异。B组肺组织线粒体破坏，呈空泡样变，C组仅见线粒体轻微肿胀。

Electron-microscopic observation: In stroke-prone spontaneous hypertension group, electron density was found increased in necrotic neurons; moreover, some nuclear membrane lost double-layer structure with ridges broken, even reduced or disappeared, displaying vacuolated changes. In losartan 30 mg/ group and losartan 10 mg/ group, most of neurons displayed basically normal morphology, with neuron chromatin evenly distributed and nuclear envelops regular, but there were still some neurons that had dense chromatin, with ridges broken and reduced.

3组大鼠脑组织电镜观察：易感型自发性高血压组大鼠坏死神经元电子密度增高，有的核膜失去双层结构，嵴断裂、减少甚至消失，呈空泡样改变；氯沙坦30mg/组和氯沙坦10 mg/组大多数神经元染色质分布均匀，核膜规整，细胞形态基本正常；少数神经元核染色质较致密，部分嵴断裂、减少。

Pathological changes occurred in all infected tissues and organs,including disintegrated cuticle,malformation and dissolution of the fat body,loose muscle fibre layout,disappearance of the midgut epithelial cells and vacuolization.

受侵的各组织器官均发生明显的病变，如体壁分离、脂肪体变形、溶解，肌纤维排列松散，中肠上皮细胞脱落并出现许多空泡等。

D. N big mouse model was successfully made by adopting single side kidney cutting with induction, then by 24 week continuos observation on the change of various values of kidney and function, through testing of immunity florescence, electro-scope and optical scope, what we can see from model group is that typical kidney small cell got hardened by knot, and discarded, and dead, also small tube withered, small cell of on base film got thick, cell capsule wall was fibred, and base film got double layered.

实验研究采用单侧肾切除加以链脲佐菌素诱导，成功地复制出糖尿病肾病大鼠模型，对其肾脏结构和功能的改变各项指标，连续进行24周动态观察，并进行免疫荧光、电镜、光镜检测，结果表明：糖尿病肾病模型组可见典型的肾小球节段硬化、废弃、坏死，有大量蛋白管型，肾小球管糖元空泡沉积及脂肪滴，肾小管萎缩，肾小球基底膜明显增厚，球囊壁纤维化，基底膜双层化，有一例结核性肉芽组织及钙化等病理变化。

Some cell dropped into the cavity and became free. Thrombosis or part organization could be seen. The internal elastic layer became thin, disappear or broken. In internal and middle layer existed fibroblasts, fibrocytes and collagen. Some of the wall indicated hyaline change, soomth muscle cell decreased greatly. The massive inflammatory cells invaded the middle and external layer. There were many foam cells in the capsule tissue. Cytoplasm was filled with fatty tissue and cholesterol. some cavities were full of thrombosis. Some thrombosis was fibrosis, the bottom was organization. The surface of the thrombosis existed red blood cell and librae.(2)Elatic fibrila staining: the internal elastic menbrane almost completely disappeared, the intact internal elastic menbran could be seen in the new small vessels.

动脉瘤管壁厚薄明显不均，全层或局部区域显著变薄向外膨出，内皮细胞空泡变性或坏死脱落，部分内皮细胞剥离并突入管腔成游离状，可见血栓形成及部分血栓机化；内弹力板变薄、消失或突然中断；在内膜及中膜部位主要为纤维母细胞、纤维细胞和大片胶原；部分动脉瘤壁呈均质状玻璃样变，平滑肌细胞明显减少；中膜和外膜可见大量的炎性细胞浸润；瘤壁组织有纤维母细胞、纤维细胞、大片胶原成分及较多泡沫细胞，胞浆内充满脂类物质及胆固醇结晶；部分动脉瘤腔内充满血栓，有的血拴已经纤维化，血栓基部机化，血栓表面有红细胞和纤维素。

HPV was also detected in the granular ladyer and whole prickle cell layer of 11 cases of CA with no typical koilocytes.

鼵A中，10例具典型组织学特征的CA均有HPV分布，主要位于表皮浅层，另 11例缺乏典型空泡细胞的 CA在颗粒层或棘细胞全层测得 HPV。

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。