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Observ ed with transmission electron microscope and scanning electron microscope, t he apoptotic nuclei showed the typical morphological feathers of apoptosis: cond ensation and margination of chromatin, bubbling of nuclear membrane and apoptoti c bodies.

在透射电子显微镜和扫描电子显微镜下都观察到凋亡的细胞核呈现典型的凋亡形态学特征,例如染色质的凝集及趋边化,细胞核表面形成空泡化结构并有大量的凋亡小体结构出现。

With the fund item sponsored by the National Laboratory of Hydrodynamics, the study on measurement method of propeller-induced pressure with using self-propulsion model has been carried out in depressurized towing tank.

在脉动压力的模型测试研究方面,本文在水动力学国家重点实验室基金项目的资助下,对在减压拖曳水池中利用自航模进行空泡螺旋桨诱导的脉动压力的测试方法进行了研究。

In both male and female worms, the tegument showed focal or extensive swelling, fusion, vacuolization, erosion, peeling, and destruction of sensory structures.

雄虫的皮层结节肿大、破溃或从皮层上剥落;在雄虫和雌虫的体表可查见有局灶性或广泛的皮层肿胀、融合、空泡变化、糜烂和剥落,以及感觉结构的破坏。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等;病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变,随CsA剂量的增加,病变呈加重趋势;结合低钠饮食,CsA慢性肾毒性病变明显加重。

The pseudopodial movement could be inhibited by calcitonin (100 μg*L-1). Lacuna formation could be found in cocultured specimens. There were fibrils on the walls of lacunae. The MGCs demonstrated positive reaction with Gomori stain. Conclusion: The results demonstrated that MGCs had the same morphological features and the bone resorption ability as the osteoclasts.

结果:倒置相差显微镜下可见多核巨细胞胞核较多(20个以上),胞浆周边不规则,有伪足样突起;胞浆内可见较多大小不等的空泡;降钙素(100 μg*L-1)可抑制多核巨细胞的伪足样运动;多核巨细胞与灭活的骨片共同培养时可见骨吸收陷窝形成,扫描电镜下可见吸收陷窝底面有原纤维;Gomori染色时可见多核巨细胞的酸性磷酸酶呈阳性。

Under inverted microscope, stereognosis of neurons died down, there were blank bulb in the neurons, dark particle were seen in the neuritis; the result of MTT test showed that the survival rate of neurons was obviously decreased. Res 40μmol/L increased the survival rate of neurons. Aβ(subscript 25~35) dose-dependently increased the level of MDA, decreased the level of GSH. Res dose-dependently increased the level of GSH, decreased the level of MDA.

结果:Aβ(下标 25~35)在终浓度为2μmol/L时神经元形态有明显的变化,细胞立体感减弱,胞体内空泡形成,细胞突起内可见黑色颗粒状物;细胞的存活能力明显下降,与对照组相比较有显著性差异(P.05);Res在终浓度40μmol/L时,能明显提高细胞的存活能力。Aβ(下标 25~35)可以明显升高细胞培养上清液中MDA含量,降低GSH的含量;Res可使细胞培养上清液中MDA含量下降,GSH含量增加。

The vacuolated effect of HP, which wa s a pathogeny found recently, was different from the effects of HP measured eve r.

结果 HP的这种空泡毒作用不同于已知的HP的致病因素,而是一种新近发现的致病因素。

METHODS HP strains were obtained by culture from patients Vero cell intracytoplasmic vacuolization was induced by Broth Culture Filtrate ( BCF, 0.22um pore filter) of 43 of 62 HP strains obtained from patients.

62株临床分离的幽门螺杆菌,43株的肉汤培养滤液(0.22um微孔滤膜)作用于体外培养的Vero细胞,能使其产生胞浆空泡样变。

Under the transmission election microscope, we had observed that the state of oocytes arid the cumulus cells around them was tightness, and there were plenty of long and thin microvilli playing the role of connection in the enwrapping. The shape of cumulus cells nucleus was ovate, and the longer and shorter diameters of the cumulus cells were 4.250±0.042μm and 2.750±0.07 μm respectively. The zona pellucida was well proportioned and tightly linking with oocyte. There were great deals of multi-crista mitochondria, lipid droplet and vacuolus. The mitochondria longer and shorter diameters were 0.600±0.106μm and 0.490±0.117μm. Granular nucleoplasma distributed very well in the cell nucleus.

电镜下,卵母细胞外的卵丘细胞紧紧包裹卵母细胞,且与卵母细胞之间有大量细长的微绒毛相联系;卵丘细胞核呈卵圆形,其长径为4250±0.042μm,短径为2.750±0.071μm;透明带均匀,与卵母细胞结合紧密;在皮质区集中分布大量的多峰型线粗体、脂滴和空泡,线拉体长径为0.600±0.106μm,短径为0.490±0.117μm;细胞核中颗粒状的核质分布非常均匀。

In addition to the spongy form vacuoles that are the hallmark of the disease, their brains were littered with large, flower-shaped plaques

除了海绵状空泡是这一疾病的标志外,他们的脑部布满了大得像花一样的斑。

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