稳定分布

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

Dealcoholization temperature markedly influences the surface area and porosity of the resultant MAO-supports. When the support was pretreated at lower or higher temperature, the corresponding MAO-support shows very low surface area;2.XRD and IR analyses indicate that MAO has reacted with the residual ethanol in the supports, which is an important manner to get MAO fixed on the carrier. Morever, XPS analyse indicates that MAO can also be coordinated with MgCl_2, which is another way to get MAO fixed on the support;3.ICP and EDX analyses indicate that dealcoholization temperature not only determined the element content on the solid catalyst, but also influences the element distribution on the carrier;4.The activities of the supported phenoxy-imine catalysts and the properties of resultant polymers are strongly dependent on the dealcoholization temperature. The support (MSP-5) obtained by treating MgCl_2·2.56C_2H_5OH at 160℃for 4 h, then modified by MAO is very effective for immobilizing complex 3, the resultant solid catalyst (MSPC-5) shows very high activity in ethylene polymerization, and its kinetics of polymerization is stable during the reaction process. Finally, PEs with spherical morphology and high bulk density (over 0.35g/ml) were obtained, without reactor fouling;5.In this work, polymerization conditions such as alkylaluminums, Al/Zr ratio, temperature and H_2 had a pronounced effect on the activity of MSPC-5 and properties of PE;(3). New MgCl_2-Supported Single-Site Catalysts for Ethylene PolymerizationIn this work, a kind of new MgCl_2 support was obtained by anhydrous MgCl_2 co-milled with solid MAO, and it is a creative contribution. Then some single-site catalysts were supported on the new MgCl_2 support, and the resulted solid catalysts were tested in ethylene polymerization, the results indicated that:1.XRD and IR analyses indicate that MAO does be coordinated with MgCl_2, which is in good agreement with the results obtained by XPS;2.co-mlling time had no obvious effect on the texture of support after 12 hours;3.In this work, MgCl_2 was co-milled with solid MAO for different hours, and then complex 3 was supported on these co-milled supports. It was found that co-milling time markedly influences the activity of solid catalysts, but it had negligible effect on the kinetic profile and the properties of resultant PE.

XPS研究结果表明，MAO不仅仅只和乙醇作用，MAO还与MgCl_2本身有一定的作用，这是一个极为重要的发现；3、通过ICP和EDX表征，发现载体的脱醇温度直接影响着元素在固体催化剂中的含量及分布；4、脱醇温度极大地影响着负载苯氧基亚胺类催化剂的活性和聚合物的性能，特别是原始载体经160℃活化4小时制备得到的固体催化剂MSPC-5的活性明显高于其他脱醇温度条件下制得的固体催化，并且催化剂寿命长，表现出稳定的动力学行为，最终获得了高堆密度(大于0.35g／ml)的球形聚乙烯颗粒；5、本文选择MSPC-5为研究对象，考察了聚合反应参数对催化剂的活性及其聚合物的影响，研究发现：不同的烷基铝对催化剂具有非常重要的影响，特别足TIBA对MSPC-5的助催化活性最高，烷基铝的加入量有一个较佳值，聚合温度为80度时活性最高，H_2的加入使催化剂的活性明显降低且聚合物的分子量也减小；、新型氯化镁载体负载单活性中心催化剂催化乙烯聚合本文创造性采用固体MAO与无水氯化镁直接进行共研磨，制备出了一种的新型的氯化镁载体，并将该载体用于多种单活性中心催化剂的负载化研究，研究表明：1、通过BET、XRD的表征，再次证实了MAO与MgCl_2之间具有直接作用，与XPS的研究结果相一致；2、当研磨时间高于12小时时，延长研磨时间对载体的结构没有显著的影响；3、将配合物3负载于共研磨时间不同的一系列载体上，乙烯聚合结果表明，尽管共研磨时间对负载催化剂的活性具有明显的影响，但是它对聚合物的性能以及催化剂的影响不明显。

Dealcoholization temperature markedly influences the surface area and porosity of the resultant MAO-supports. When the support was pretreated at lower or higher temperature, the corresponding MAO-support shows very low surface area; 2.XRD and IR analyses indicate that MAO has reacted with the residual ethanol in the supports, which is an important manner to get MAO fixed on the carrier. Morever, XPS analyse indicates that MAO can also be coordinated with MgCl_2, which is another way to get MAO fixed on the support; 3.ICP and EDX analyses indicate that dealcoholization temperature not only determined the element content on the solid catalyst, but also influences the element distribution on the carrier; 4.The activities of the supported phenoxy-imine catalysts and the properties of resultant polymers are strongly dependent on the dealcoholization temperature. The support (MSP-5) obtained by treating MgCl_2·2.56C_2H_5OH at 160℃for 4 h, then modified by MAO is very effective for immobilizing complex 3, the resultant solid catalyst (MSPC-5) shows very high activity in ethylene polymerization, and its kinetics of polymerization is stable during the reaction process. Finally, PEs with spherical morphology and high bulk density (over 0.35g/ml) were obtained, without reactor fouling; 5.In this work, polymerization conditions such as alkylaluminums, Al/Zr ratio, temperature and H_2 had a pronounced effect on the activity of MSPC-5 and properties of PE;(3). New MgCl_2-Supported Single-Site Catalysts for Ethylene Polymerization In this work, a kind of new MgCl_2 support was obtained by anhydrous MgCl_2 co-milled with solid MAO, and it is a creative contribution. Then some single-site catalysts were supported on the new MgCl_2 support, and the resulted solid catalysts were tested in ethylene polymerization, the results indicated that: 1.XRD and IR analyses indicate that MAO does be coordinated with MgCl_2, which is in good agreement with the results obtained by XPS; 2.co-mlling time had no obvious effect on the texture of support after 12 hours; 3.In this work, MgCl_2 was co-milled with solid MAO for different hours, and then complex 3 was supported on these co-milled supports. It was found that co-milling time markedly influences the activity of solid catalysts, but it had negligible effect on the kinetic profile and the properties of resultant PE.

XPS研究结果表明，MAO不仅仅只和乙醇作用，MAO还与MgCl_2本身有一定的作用，这是一个极为重要的发现； 3、通过ICP和EDX表征，发现载体的脱醇温度直接影响着元素在固体催化剂中的含量及分布； 4、脱醇温度极大地影响着负载苯氧基亚胺类催化剂的活性和聚合物的性能，特别是原始载体经160℃活化4小时制备得到的固体催化剂MSPC-5的活性明显高于其他脱醇温度条件下制得的固体催化，并且催化剂寿命长，表现出稳定的动力学行为，最终获得了高堆密度(大于0.35g／ml)的球形聚乙烯颗粒； 5、本文选择MSPC-5为研究对象，考察了聚合反应参数对催化剂的活性及其聚合物的影响，研究发现：不同的烷基铝对催化剂具有非常重要的影响，特别足TIBA对MSPC-5的助催化活性最高，烷基铝的加入量有一个较佳值，聚合温度为80度时活性最高，H_2的加入使催化剂的活性明显降低且聚合物的分子量也减小；、新型氯化镁载体负载单活性中心催化剂催化乙烯聚合本文创造性采用固体MAO与无水氯化镁直接进行共研磨，制备出了一种的新型的氯化镁载体，并将该载体用于多种单活性中心催化剂的负载化研究，研究表明： 1、通过BET、XRD的表征，再次证实了MAO与MgCl_2之间具有直接作用，与XPS的研究结果相一致； 2、当研磨时间高于12小时时，延长研磨时间对载体的结构没有显著的影响； 3、将配合物3负载于共研磨时间不同的一系列载体上，乙烯聚合结果表明，尽管共研磨时间对负载催化剂的活性具有明显的影响，但是它对聚合物的性能以及催化剂的影响不明显。

On the basis of census of all individuals of the populations at different plots, the structure and dynamics of the populations were described. The result showed that P. tabulaeformisf.shekannesis were growing populations, and the distributions of the structure were reverse J. The density decreased with the increasing of Size-class structure. The populations developed the characteristic of increasing in the early stage and stabilizing in the late. The survive curve of Pinus tabulaeformisf.shekannesis were between DeeveyⅡand DeeveyⅢ. The analysis of time sequence showed that most of the inividuals would be adult after 20 years.

结果表明：柴松种群结构呈反J分布型，种群处于增长阶段；种群的密度随径级的增加而降低，种群密度与径级呈现出明显的负相关；四个函数估计值说明柴松种群具有前期增长、后期稳定的特点，其存活曲线介于DeeveyⅡ型和DeeveyⅢ型之间；随时间推移，种群中树和大树数量逐渐增多，种群在20年后开始大量进入成熟阶段。

Thunbergii trees were established, and the sun survivorship curves were drawn with field data. The results showed that in the three plots, the height and basal diameter growth of regenerated young P. thunbergii trees had exponential, linear, and quadratic functional relations with age and the age structure was of spindle, discrete, and pyramid types, respectively. Most of the regenerated young trees were distrbuted at 0.3-1.2 m from their nearest standing trees, and the individuals of the young trees decreased near to or far from the nearest standing trees. Inplots Ⅰ and Ⅲ, the expected average life of regenerated young P. thunbergii trees had a decreasing trend with their increasing age, and the survival number of the population also decreased with increasing population age. The survivorship craves of regenerated young P. thunbergii trees in the two plots approximated to the type of Deevey Ⅱ, indicating that the young P. thunbergii populations in the plots were at stable development stage. The population structure of regenerated young P. thunbergii trees in plot Ⅱ was lesser integral, suggesting that the population was of declining types being related to human disturbance, slope and other environmental factors.

结果表明：(1) 3个样地中幼龄植株高生长、基径生长与年龄均分别呈指数函数、直线和二次函数关系；(2) 3个样地黑松幼龄植株年龄结构存在着明显差异，分别表现为纺锤形、残缺型和金字塔型；(3)幼龄植株主要集中分布在距最近立木0.3~1.2m，离立木越近或越远幼龄植株均逐渐减少；(4)对样地Ⅰ和样地Ⅲ黑松幼龄植株生命表和存活曲线的分析表明，随年龄的增加，黑松幼龄植株生命期望值基本上呈递减趋势，黑松幼龄植株种群存活数也随着年龄的增加而降低；样地Ⅰ和样地Ⅲ黑松幼龄植株种群存活曲线近似于Deevey Ⅱ型，表明2个样地黑松幼龄植株种群处于稳定发展阶段；(5)样地Ⅱ幼龄植株种群结构很不完整，表明该种群属于衰退型，与人为干扰及坡度等有关。

In addition, the density of composite matrix could be controlled by altering the densifier addition to match the requirement of varying fluid velocity and expansion factor in expanded bed.

复合层析基质的柱层析行为表明：大孔型基质的洗脱峰形明显改善，柱压小，适合于高流速的固定床和扩张床层析；扩张床内可形成稳定的分级分布，符合扩张床吸附要求；可根据具体需要，调节碳化钨添加比例来优化操作流速和床层扩张率。

The wide area controller design using remote signal has been suggested to improve the dynamic performance of interconnected power systems. Because of the nature of wide area control, communication delay can't be ignored. Delay may be deteriorative to close-loop system stability.

广域控制策略可以有效提高广域分布互联电力系统的动态性能，但是广域控制信号传输时延会对控制器产生负面影响，并且日趋复杂的系统结构及接近稳定极限的运行条件对控制器的鲁棒性能提出了更高的要求。

It has been shown that the compound treatment can not only result in a considerable degree of desulfuration and cleanliness of steel, but also bring unique inclusion mordifyingeffect of RE into full play: Harmful effects of inclusions to the performance of steel can be eliminated by Rare Earth additions through formation of dispersively distributed, undeformable and stable Rare Earth sulphide and oxysulfide in place of elongated MnS.

结果表明：复合处理不仅可以脱硫、净化钢液，而且充分发挥了稀土的变质夹杂物的特性：稀土金属可以将钢中原有的条状硫化锰夹杂转变为在钢中均匀分布、不易变形的、稳定的球形稀土硫化物和硫氧化物，从而可以消除夹杂对钢材造成的不利影响。

The results show that weight average molecular, molecular weight distribution and the dissociative sulfate content of 916 do not change obviously. It shows that 916 is stable by lysozyme and trypsin...

结果表明：在所选定的实验条件下，916的重均分子量、分子量分布系数和游离硫酸根含量均未发生显著变化，表明在所选择的实验条件下 916对溶菌酶和胰蛋白酶是稳定的。

In this paper, a new dyeable fine polypropylene filament whose dpf was less than 1 dtex has been prepared by admixing polyolefine additive to the polymer prior to melt extrusion and it was practically proved that the spinning process was stable.

本课题首次找到并合成了具有适宜分子量和分子量分布的聚烯烃类添加剂，将其加入到熔融的聚丙烯中，纺制出dpf小于1dtex的细旦可染聚丙烯长丝，并且纺丝过程稳定。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。