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There were 15 pediatric ALL patients, which had received 50 times of chemotherapy with HD-MTX. The records about blood concentration of MTX and clinical conditions for 50 times chemotherapy were divided into two groups. Group I: contained 25 records of stand-risk patients, administering MTX 3.0g/m2; Group II: contained 25 records of mid and high-risk patients, administering 5.0g/m2. Continuous intravenous dripped MTX for 24th in both two groups, while implemented hydrating and alkalizing for 4 days. All patients were rescued 6 times through leucovorin, 15mg/m~2, since 12th after the end of MTX dripping. Then examined the blood concentration of MTX by fluorescence polarization immunoassay approach at 24h, 44h, 68h, at the same time inspected liver function, blood routine examination, the occurrence time and degree of toxicological reactions.

观察15例ALL住院患儿,接受大剂量MTX共50例次,按ALL危险度分2组,低危治疗组接受MTX剂量为3.0g/m2为I组;中高危治疗组接受MTX剂量为5.0g/m2为II组,连续静脉点滴MTX共24小时,同时给予水化碱化治疗,共4天,全部病例均在MTX滴注结束后12小时开始静脉推注四氢叶酸钙(leucovorin,LV)解救,15mg/m2/次,共6次,采用免疫偏振荧光法检测药物滴注24、44、68小时MTX血药浓度,同时检测两组病例的肝功、血常规,观察临床出现MTX毒副反应的时间及程度,观察每个病例毒副反应出现程度与MTX血药浓度关系,两组毒副反应程度比较,进行统计学分析。

Results: 1. The value of all experimental indexes decreased significantly after heat stress, and reached the lowest at the time 2-8 hours after heat stress. This indicates that the immunity of the mice is damaged to the largest extent at 2-8 hours after heat stress. 2. L-arginine supplementation with appropriate dose could remit the acute atrophying of thymus and spleen tissue caused by heat stress. 3. After L-arginine supplementation with appropriate dose, the lymphocyte proliferation, the level of concentration of IL-2 and * expression of IL-2R raised in the group with room temperature; in the heat stress group the level of three indexs decrease significantly. Furthermore, the decrease of the group given 1 .Smglg.bw L-arginine is the smallest. This result indicates that the concentration of 1 .Smglg.bw L-arginine supplementation could remit the depressment of the immunity caused by heat stress. 4. The [Ca2~] in activated thymocytes of the group with L-arginine -2- supplementation is significantly higher than that of the group with water supplementation. This indicates that L-arginine supplementation could protect thymoeytes of mouse under heat stress. We also found that the fluorescence intensity of [Ca2~] in activated thymocytes of the group given 1 .Smglg.bw L-arginine is the highest.

结果:1、热应激后小鼠的各项免疫指标均有显著性下降,其中在2.8小时降到最低,提示在这个时间段小鼠的免疫功能受到最大损害;2、适量补充精氨酸有助于缓解热应激导致小鼠胸腺和脾脏的急性萎缩;3、常温组,补充适量精氨酸后小鼠淋巴细胞增殖活性、IL-2的浓度及IL-2R的表达均有显著性上升,而热应激后三指标均显著降低,其中在精氨酸给予浓度为1.5mg/g.bw时三指标的降低程度最少,提示该浓度可最大程度缓解热应激对小鼠免疫功能的抑制;4、补充精氨酸组的活化胸腺细胞[Ca~(2+)]较给水组有显著性上升,说明精氨酸对热应激小鼠胸腺细胞具有保护作用,并发现在精氨酸给予浓度为1.5mg/g.bw时活化胸腺细胞的胞浆钙离子荧光强度达到最大;5、热应激后小鼠血清NO的浓度均有不同程度的上升,补充精氨酸后血清NO上升更加明显,但并非随精氨酸给予浓度的增加而增加。

The result is that their development levels have notable positive correlation and it is more and more notable year after year.

结果表明:因特网发展程度与经济发展水平之间有明显的正相关联系,这种相关关系逐年增强;因特网发展的区域差异程度高于经济发展的差异程度,但随着时间推移有下降趋势。

Results there are 45.1% of selected students, who were different obtruding symptom, and significant differences were found between poverty and general students.

结果 有45.1%的大学生存在不同程度的强迫症状,贫困生和非贫困生在这方面差异显著;36%的大学生存在不同程度的人际敏感,并且他们之间的差异不显著;30%的大学生存在不同程度的偏执,贫困生与非贫困生之间差异显著。

The purpose of this experimental study was to examine the effects of massage on women's pain perception and anxiety during labor. The subjects were primiparas who had a normal spontaneous delivery at a regional hospital in southern Taiwan. They are randomly assigned to either the experimental or the control group. The experimental group received massage intervention and the control group did not. The intensity of pain perception and anxiety between the two groups were compared in the latent phase (the cervix dilated 3-4cm), active phase (5-7cm) and transitional phase (8-10cm). The relationship between pain perception and anxiety level was also examined.

中文摘要本研究的目的在检视按摩对分娩妇女之疼痛感受与焦虑程度的影响,研究对象为南部某区域医院自然生产的初产妇,60位产妇随机分派至实验组与对照组,实验组接受按摩措施,对照组则无接受按摩措施,於待产期间比较两组产妇在潜伏期、活动期及过渡期中疼痛感受与焦虑程度之差异,并探讨疼痛感受与焦虑程度的关系。

The article will appear on the market through simultaneous equations model policy of company cash dividend and capital embezzlement union rise consideration, discovery is state-owned accuse the cash dividend level that the company grants is advanced and first-order state-owned legal person accuses paragraph of highest; company, the level that cash dividend extends is in hind two level are top, but capital is accused by the legal person of society of degree lowest; of embezzlement a partner is manual operated to the preference of cash dividend and state-owned law a partner as good as, but its accuse company capital by the degree of embezzlement most serious; is state-owned accuse company, its capital is uprighted by the degree of embezzlement between both.

本文通过联立方程模型将上市公司现金股利政策与资金侵占结合起来考虑,发现国有控股的公司发放的现金股利水平在前一阶段最高;国有法人控股的公司,现金股利发放的水平在后两阶段最高,但资金被侵占的程度最低;社会法人控股股东对现金股利的偏好与国有法人控股股东无异,但其控股的公司资金被侵占的程度最为严重;国有股控股的公司,其资金被侵占的程度介于二者之间。

In particular, an investigation was carried out into the different temperatures used on the degradation of sugars and amino acid and the extent of accumulation of browning intermediates, such as Amadori product, organic acid, brown pigment formation and pH changes.

研究了在不同反应温度(80、100、120℃)和不同反应时间下,体系中糖和氨基酸的降解程度,反应中间体:阿利德诺和有机酸的累积程度,类黑素的形成及pH变化程度

It was believed that either alumina reacted with impurities in the iron powder or the surface diffusion caved the alumina particles to stick to the iron powder surfaces. Another approach was to use the air classifier mill to break up the sintered iron cakes into powders. The morphology of such particles was classified into 4 types in this study: irregular, equalaxed, near spherical, and flaky. The morphological differences were affected by the extent of sintering. The higher the extent of sintering, the stronger the inter-particle bonding.

此外,本实验利用空气分级气流粉碎机将还原后的烧结体进行粉碎,实验结果显示粉碎后的粉末形貌可以分为四种,不规则形、等轴形、近球形和片形,形貌上的差异是由於还原时铁粉烧结程度的不同,烧结程度越高,粉末间键结强度越强,因此粉碎过程中会产生高程度的塑性变形,以至於粉末形貌越来越接近球形,最后因粉末表面大量加工硬化产生破裂,形成片状碎屑。

This indicates that these HA have similar compositions, but different structures and properties.Results from analysing E465/E665 are the same as those obtained by analysing molecule structure using colour index coefficientΔ~ K.Compassion study of HA in NaOH and NaHCO_3 solutions show that the absorption peaks shift towards the direction of longer wavelength.

这几个吸收带的变化证明了以紫色潮土HA、石灰性黄壤HA、中性紫色HA、酸性紫色HA、腐殖土HA为序的腐殖酸的芳构化度降低、缩合程度下降的观象,说明腐殖土HA其分子在苯环C骨架的聚合程度、芳构化度和分子复杂程度等上均最小,与紫外光谱分析结果一致。

The degree to which a dog is penalized should depend upon the extent to which the dog deviates from the standard and the extent to which the particular fault would actually affect the working ability of the dog.

根据其背离上述标准的程度,来确定其缺陷的严重程度。此外,一些细节缺陷要看对工作能力的影响程度而定。

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推荐网络例句

However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。