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OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数,优化给药方案,设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式,CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发,在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物,适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上,结合病人个体特征,以1,2个血药浓度作为反馈,即可拟合估算个体药动学参数,优化给药方案结论经初步应用,CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

The character of integration calls for improving the design quality of process operations and suggests that it should be studied with the help of process control system blockdiagram. The character of optimization indicates that the design of operating procedures must be based on process simulation.

其中,操作程序的集成化特征对操作程序设计提出了改进过程操作设计品质的要求,启发了结合过程控制系统方块图进行研究的思路;而操作程序的动态最优化特征则明确了操作程序设计问题必须以过程建模与仿真为工作基础的思想。

These three compilers stand for the most prevalent trend of the software development.Other compiling and developing environment such as Boland C++,can also be brought into the courses to get better teaching effect. C Program design ; Quality Education ; Experimentation ; Teaching Reform and Innovation

C程序设计》课程以C语言为核心,不论是我们日常交流的自然语言,还是高级程序设计语言之一的C语言,无不都是为满足特定环境下的使用应运而生的。C语言作为结构化的程序设计语言,既适合于开发系统程序,又适合开发应

Another MCU, 89C2051 is used to realize the control of the three rows LED monitor showing coordinates of axis X and Z axis and other state of the system. Charnel A and C of 8155 are used for editor keyboard, which make the inputting or editing of the NC code and data possible. Charnel P1 of 8031 is used for the operation keyboard such as system power on/off and movement of axis X or Z. a programmable parallel I/O chip, 8255, is used to achieve system I/O and the transmission of other information. In summarize, the system developed is characterized by its simplicity, low development cost and high reliability.

在CPU存储器扩展电路设计中, CPU选用MCS-51系列的8031单片机,外扩32K的程序存储器和 8K的数据存储器,分别用于存放系统管理程序、数控加工程序以及运算数据;在显示电路设计中,选用MCS-51系列的89C2051单片机作为从CPU,控制三排LED显示器,用于X轴、Z轴动态坐标以及相关数字的动态显示;在手动键盘和编辑键盘设计中选用8155芯片的PA口和PC口作为行、列母线,扩展矩阵式编辑键盘,用于程序和数据的输入或编辑,同时选用8031单片机的P1口扩展手动键盘,用于系统启动、停止以及运动部件在X、Z轴方向的手动控制;在I/O口扩展电路设计中选用8255芯片扩展输入输出口,用于接收和传送开关量及相关信息。

The author mainly presents his ideas in this thesis from the following aspects: To perfect Chinese sports law, China should have its own sports arbitration system so that the law could catch up with the development of Chinese sports and international sports as well; Sports arbitration should aim at fairness and effectiveness; The popularity of sports arbitration institutions and the lawfulness of arbitration procedures and verdict effect make sports arbitration quasi-judicial; As long as sports arbitration is listed in the regulations of sports organizations, it could be applied for its compulsiveness; Sports arbitration is supposed to address the disputes caused by the disciplinary punishment, and that caused by the such major problems like the registration, circulation, and qualifications of the sportsman, and disputes caused by the contracts in sports activities; Mediation procedure and immediate arbitration procedure should be given special attention in the establishment of arbitration procedures; Sports arbitrators should be neutral in solving disputes, and should be a qualified sports worker.

本文认为,为完善中国体育法制建设,适应中国竞技体育发展的实际需求并与国际惯例接轨,中国应尽快设立体育仲裁制度;体育仲裁的价值目标应该是公正和效益;体育仲裁机构的民间性及仲裁程序和裁决效力的司法性,使得体育仲裁的性质具有准司法性;体育仲裁具有强制性的特征,只要体育组织的章程中有体育仲裁的规定,即可申请体育仲裁;体育仲裁的范围应限于竞技体育领域中因体育组织的纪律处罚所引起的纠纷,因运动员注册、流动、转会以及参赛资格等体育专业问题所引起的纠纷,因竞技体育活动中的合同关系所引起的纠纷。体育仲裁的程序建构要突出调解程序和快速仲裁程序;体育仲裁员必须确保中立并且其素质群中还应具备体育知识的素质。

The author mainly presents his ideas in this thesis from the following aspects: To perfect Chinese sports law, China should have its own sports arbitration system so that the law could catch up with the development of Chinese sports and international sports as well; The popularity of Sports arbitration institutions and the lawfulness of arbitration procedures and verdict effect make sports arbitration quasi-judicial; As long as sports arbitration is listed in the regulations of sports organizations, it could be applied for its compulsiveness; sports arbitration is supposed to address the disputes caused by the such major problems like the registration, circulation, and qualifications of the sportsman, and disputes caused by the contracts in sports activities; Mediation procedure and immediate arbitration procedure should be given special attention in the establishment of arbitration procedures; Sports arbitration should be neutral in solving disputes, and should be a qualified sports worker.

本文认为,为完善中国体育法制建设,适应中国竞技体育发展的实际需求并与国际惯例接轨,中国应尽快设立体育仲裁制度:体育仲裁机构的民间性以及仲裁程序和裁决效力的司法性,使得体育仲裁的性质具有准司法性;体育仲裁机构应具有民间性特征,体育仲裁员必须确保中立并具有体育知识素质;体育仲裁具有强制性的特征,只要体育组织的章程或规则中有体育仲裁的规定,即可申请体育仲裁;体育仲裁的范围应限于竞技体育领域中因体育组织的纪律处罚所引起的纠纷,因运动员注册、转会、流动以及参赛资格等体育专业问题所引起的纠纷,因竞技体育活动中的合同关系引起的纠纷等;体育仲裁的程序建构要突出调解程序和快速仲裁程序;体育仲裁也应具有类似于国际商事仲裁的"一裁终局"的效力;由于自身的缺陷,法院可以对体育仲裁裁决予以适当的司法审查,给当事人一个程序化的救济权利的机制。

844 Is a graduate introduction to programming theory, logic of programming, and computability, with the programming language Scheme used to crystallize computability constructions and as an object of study itself.

6.844是一份研究介绍程序理论、程序逻辑和运算逻辑,程序语言计划可以明确性的表达运算结构,也成为了学生学习程序语言计划的目标。

21 Chapter 5 Operating System 5.1.2 User interface related functions These computational structures will be defined and described in later chapters; here we only point out a few salient features. It is assumed that each program is individually initiated by the user through the user interface.

例如每个程序都是由用户通过用户接口分别进行初始化的,例如每个程序都是由用户通过用户接口分别进行初始化的,单一程序是由在给定的数据集上的一个程序执行组成的,用户通过命令启动程序

Selecting in-house software of sub-routines to run in connection with program; writing machine instruction, testing , debugging, and assembling program; documenting overall system and developing data control procedures; advising and instructing less experienced programmers and offering operating instructions.

选择同程序相关的机内软件或予程序;编制计算机指令;检测、改正程序中的差错并组合程序;编制总系统并制定数据控制程序;指导经验不足的程序员并给予操作指导。

Selecting in-house software of sub-routines to run in connection with program; writing machine instruction, testing , debugging, assembling program; documenting overall system developing data control procedures; advising instructing less experienced programmers offering operating instructions.

选择同程序相关的机内软件或予程序;编制计算机指令;检测、改正程序中的差错并组合程序;编制总系统并制定数据控制程序;指导经验不足的程序员并给予操作指导。

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推荐网络例句

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。