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At the contralateral side, an ischiac bone graft (baseline 3 4 0.87) was transplanted. The healing period was 5 months. Group A11: The animals were treated in the same manner as in Group A5 with the difference that the healing period was 11 months. Group B5: The animals were treated in the same manner as in Group A5 with the difference that an e-PTFE membrane was adapted oer the bone graft on each side of the jaw.

愈合时间为5个月。A11组:用与A5组相同的方法处理小鼠,愈合时间为11个月。B5组:处理小鼠的方法与A5组相同,在每侧颌骨的骨移植物上方各置一片e-PTFE膜。B11组:实验方法与B5组相同,但在骨移植5月后,进行第二次手术取出生物膜,愈合时间为11个月。z在下颌骨骨量增加后,分别于第5个月处死A5组及B5组的小鼠,第11月处死A11组及B11组的小鼠,取下颌骨标本,体式显微镜测量骨移植物的宽度、长度及高度。

We suggest that subclinical TG is an under-recognized cause of antibody-mediated, chronic renal allograft injury which may be mechanistically distinct from other causes of nephropathy.

我们认为亚临床TG是一种未被认识的抗体介导的移植肾慢性损伤的诱因,其可以独立于其他导致肾小球病的因素之外。

Successful transplant and test of WRF in DeepComp6800 will greatly contribute to the research and application of numerical meteorologic forecast in CNGrid.

WRF在深腾6800上的成功移植与测试,也为进一步将WRF应用于中国国家网格奠定了研究基础。

Our results suggest that FGF-2 should be tested for its ability to maintain the reactivity of the nucleus pulposus cells to other morphogenic factors that may be used for cell-based transplantation therapy.

我们的研究说明应该对FGF2保持髓核细胞对其它形态发生因子的反应性从而可能使其应用于细胞移植疗法进行研究。

Our results suggest that FGF-2 should be tested for its ability to maintain the reactiity of the nucleus pulposus cells to other morphogenic factors that may be used for cell-based transplantation therapy.

我们的研究说明应该对FGF2保持髓核细胞对其它形态发生因子的反应性从而可能使其应用于细胞移植疗法进行研究。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

ConclusionAutologous fat transplantation in myringoplasty is an ideal operation way applicable to middle and small perforation of tympanic membrane.

自体脂肪移植鼓膜修补术适用于中、小鼓膜穿孔,是一种理想的手术方法。8} 2f,百拇医药

Hence we analyzed the impact of fetal exposure to noninherited maternal antigens of the HLA-A,-B antigens, or -DRB1 alleles on the outcome of CB transplants.

因此,我们分析胎儿暴露于非遗传性母体抗原(HLA-A、-B抗体或或-DRB1等位基因)对CB移植结果的影响。

Any of various early blooming oleaceous shrubs of the genus Forsythia; native to eastern Asia and southern Europe but widely cultivated for their branches of bright yellow bell-shaped flowers.

任何一种早期盛开的木犀科灌木,属于连翘属植物种;原产于亚洲东部和欧洲南部,但由于其枝条和明亮的黄色钟状的花而广被移植。

Fixation as a rule is best furnished by internal or external metallic devices. Only in an extremely unusual situation would a cortical onlay graft be indicated for fixation, and then only in small bones and when little stress is expected.

一般情况下固定最好借助于内、外金属器械,只有在极为特殊的情况下才选用皮质骨贴附移植作为固定手段,而且只用于短骨和应力很小的情况下。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。