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Autosomal dominant polycystic kidney disease , one of the most common monogenetic human disorders, is characterized by the formation and progressive expansion of multiple cystic lesions, which compromise the function of normal renal parenchyma and lead to nearly 10% of cases of end-stage renal failure in adults.

中文题名角质细胞生长因子在ADPKD肾囊肿组织中的表达及对囊肿衬里上皮细胞增殖作用的研究副题名外文题名 Expression of keratinocyte growth factor in ADPKD cystic tissue and effect of proliferation on ADPKD cyst-lining epitheliar cells 论文作者刘沙勤导师梅长林朱有华教授学科专业内科学研究领域\研究方向学位级别博士学位授予单位第二军医大学学位授予日期2002 论文页码总数104页关键词角质细胞生长因子肾病囊肿衬里上皮细胞株肾囊肿馆藏号BSLW /2003 /R692 /1 ADPKD是人类为之付出昂贵代价的一种全身性遗传性疾病,是引起慢性肾功能衰竭的第四位病因,在临床上以肾脏满布大小不一并不断增大的囊性液泡、最终引起肾功能进行性损害为特征性的改变。

To address this question in an unbiased and genome-wide manner, we developed a new method, methylation-specific digital karyotyping, and applied it to epithelial and myoepithelial cells, stromal fibroblasts from normal breast tissue, and in situ and invasive breast carcinomas.

为了能无偏向地并在基因组范围解答这个问题,我们开发了一种新的方法——甲基化特异性数字染色体组型,并将这一方法应用于上皮细胞和肌肉上皮细胞、正常乳腺组织来源的基质成纤维原细胞、原位及侵入性乳腺癌细胞。

On the other hand, the properties applications and synthetic method of Naringin dihydrochalcone and Neohesperidin dihydrochalcone , discussed detailedly.

同时,对柚皮甙二氢查尔酮和新橙皮甙二氢查尔酮两种甜味剂的性质、用途、合成方法、应用前景做了详细介绍。

More than mere color-changers, Mimic Octopi are also shape-shifters that can adapt their movements and the arrangement of their parts to appear as up to 15 different oceanic species "including sea snakes, lionfish, flatfish, brittle stars, giant crabs, sea shells, stingrays, flounders, jellyfish, sea anemones, and mantis shrimp."

章鱼 章鱼不仅仅是变色高手,拟态章鱼还能适应环境而改变自己的身体形状,甚至它还可以模拟至少15种海洋动物,其中包括:海蛇、蓑鲉、比目鱼、海蛇尾、大螃蟹、海螺、黄貂鱼、比目鱼、海蜇、海葵和皮皮虾等。

The biggest skin defect was 14 cm x 20 cm in size. Skin defects were repaired with flaps, myocutaneous flaps, free skin grafts and suturations. There were 4 gastronomies flaps, 6 latissimus flaps, 2 tensor fascia lata myocutaneous flaps, 1 transverse recuts abdominis myocutaneous flap, 5 plantaris medialis flaps, 3 random flaps, 12 free skin grafts and 5 suturings.

采用 7种不同类型的皮瓣、肌皮瓣、游离植皮和手术后直接缝合等方法进行修复,其中腓肠肌皮瓣 4例,背阔肌皮瓣6例,阔筋膜张肌皮瓣 2例,腹直肌皮瓣1例,足底内侧皮瓣 5例,邻近皮瓣3例,游离大块植皮1 2例,肿瘤切除后直接缝合5例。

Seven chemical constituents were identified on the basis of chemical methods and spectral evidences. ResultsFrom this plant, seven active compounds were isolated. They were determined as farrerol, myricetin ,quercetin, taxifolin, umbelliferone, hyperin and juniper camphor.

结果从满山红中分离得到了7种活性化合物,分别为杜鹃素,杨梅素,槲皮素,二氢槲皮素,伞形花内酯,金丝桃苷,杜松脑。

The mitochondria were highly bloated, accompany with disappeaance of the cristae and vacuolation of matrix.

未经光照的大鼠鼻粘膜VEGF、EGF和FGF主要表达在上皮和血管内皮;随着照射及其时间延长,上述三种因子蛋白在粘膜上皮和血管内皮表达明显增强。

The depilating composition for less thiolase process and the piling depilation method therewith features that leather blank in 100 portions, proteinase in 0.1-0.6 portion, sodium sulphide in 0.1-0.8 portion, sodium chloride in 0.1-3 portions, surfactant 0.1-1 portion and hydrogen peroxide in 0-5 portions are dissolved or dispersed in water of 7-15 portions while adding rice bran in 1-4 portions and kaolin in 0.5-3 portions to form paste mixture; and the leather blank is then brushed manually to make the mixture adhered onto the inside of the leather blank, piled with inside to inside in hot room at 15-35 deg.c for 20-30 hr, and depilated manually after the hair becomes loose.

一种少硫酶脱毛组合物及其堆置脱毛方法,其特点是将皮坯100份、蛋白酶0.1-0.6份、硫化碱0.1-0.8份、氯化钠0.1-3份、表面活性剂0.1-1.0份和过氧化氢0-5份依次溶入或分散于水7-15份中,并加入米糠1-4份和高岭土0.5-3份的混合物调至糊状,用毛刷手工涂于浸水去肉后的皮坯的肉面上,要求涂糊均匀,然后肉面对肉面堆置,放入温度为15-35℃的温房内,时间约为20-30小时,待毛松动,进行手工推毛。

Objective To explore a new method to harvest large full-thickness skin grafts.

目的:探讨一种新的大面积全厚皮片取皮方法。

The basolateral M cell surface is invaginated to form an intracellular central pocket into and out of which lymphocytes and macrophages.

M细胞是一种特化的上皮细胞,多分布于Peyer's结圆顶区的周边,FAE的顶端未见M细胞;其结构有别于相邻的肠上皮细胞,表面没有长而整齐的微绒毛,取而代之的是粗而短的微皱褶,胞质内终末网不发达,溶酶体较少,基底膜向顶部穹隆状突起,形成一&口袋&样结构,其中含有多个免疫活性细胞。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。