神经营养的

The biggest area was 18cm×13cm,and the smallest was 4.5cm×10cm.there were 6 cases osteomyelitis with bone exposure,4 cases muscle tendonexposure.donor-area direct suture or plant skin.resultsall flaps survived,several cases flap were fat and clumsy and need make them thin in second intention.conclusionthe clinical result of repairing soft tissue defects in lower part of shank, the foot, with antidromic island flap providing blood supply by suralis nerver is reliable.the operation is sinple, without sacrifice of major arteries, low infection to foot, convenient for application.

其中骨髓炎骨外露6例，肌腱外露4例。供区直接缝合或植中厚皮片。结果：术后皮瓣完全成活，个别病例术后较臃肿，待二期将皮瓣修薄。结论：应用腓肠神经营养血管逆行岛状皮瓣修复小腿中下段及足部创面的临床效果可靠，手术操作简便，不牺牲小腿主要血管神经，对足部影响较小，便于推广开展。

Objective : To observe of expression of NT-3 of the conus medullaris neuron with cauda equina compressed injury .

目的：探讨马尾神经压迫性损伤后不同时间骶髓神经元中神经营养因子-3的表达变化。

The table of contents include 15 parts, early events in neural development; neuronal differentiation; pattern and positional information; movement and migration of neurons; axon outgrowth and the generation of stereotyped nerve patterns; neuronal death during development; trophic effects of targets on neurons; long-term effects of neurons on their targets; formation of synapses; selective synaptic connections; the molecular basis of neuronal recognition; rearrangement of developing neuronal connections; maintenance and modifiability of synapses; the development of behavior; principles of neural development.

内容包括15部分，早期神经发育事件；神经细胞分化；模式与位置信息；神经元运动及迁移；轴突生长与固定的神经模式的形成；发育过程中的神经细胞死亡；对神经细胞靶向的营养效应；神经细胞对它们靶向的长期效应；突触形成；选择突触连结；神经细胞识别的分子基础；发育过程中神经细胞连结的重置；突触保持和改变；行为发育；神经发育原理。

Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Cortis tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL／6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像；②获得了各种听功能密切相关的结构的成熟时间点，基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14)；③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点：④Calbindin在E16以后的螺旋神经元没有表达，但是在scarpa神经元持续表达。

Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Corti\'s tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL／6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像；②获得了各种听功能密切相关的结构的成熟时间点，基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14)；③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点：④Calbindin在E16以后的螺旋神经元没有表达，但是在scarpa神经元持续表达。

Objective To detect the expression of β-NGF, p75NTR and hair follicle stem cell specific markers in vibrissa hair follicle of rat embryo. Methods Using frozen section and immunohistochemistry to detect the expression of β-NGF and p75NTR.

目的 研究胚胎大鼠触须毛囊隆突区β-神经生长因子、p75神经营养因子受体(p75NTR)与毛囊干细胞特异标志物的表达规律。

Using acupotomology incise and separate the hip joint articular capsule and ligament and the periosteum on the collum ossis femoris and the soft tissue nearby the joint can cause slight hurt and haemorrhage. The hurt factor is release from the local tissue. Human self-rebuilding system is activated, Building bone function of osteoblast is accelerated, new bone is built quickly. New blood vessel and nerve ending is rebirth. Local tissue's blood supply and nerve nourishment is improved. The developing of bone necrosis is prevented. The necrotic part is re-blood vessel. The conditions of the necrotic's absorbing tissue and the new bone's replacing are established.

针刀治疗股骨头无菌性坏死是通过针刀对髋关节囊、关节囊韧带、股骨颈的骨膜和髋关节相邻周遍组织切割分离铲拨松解可以产生轻微创伤、出血、局部组织释放创伤因子，激发人体自我修复重建反应，激活成骨细胞造骨功能，加速新骨生成，促进新血管和神经终端组织再生与重建，使局部组织血流加速，改善血液供应和神经营养状况，阻止坏死进一步发展，使股骨头颈坏死区域再血管化，为坏死组织吸收和为新骨再生爬行替代过程创造条件。

Acupuncture treatment can protect the optic nerve from elevated IOP,by alleviated the damages of the retinal and optic nerve axons ultrastructure induced by chronic ocular hypertension,preventing the apoptosis of RGCs,accelerate NO and glutaminic acid remove in rabbits retina and enhanced the expression level of Bcl - xl and BDNF in retina

针刺能有效保护高眼压下的视神经，作用主要表现为减轻视网膜、视神经超微结构损伤，减少阻断或防止视网膜神经节细胞的凋亡，减轻NO、Glu对视网膜神经节细胞毒性作用，上调视网膜抗调亡基因Bcl-xl和神经营养因子BDNF的表达。

Objective To explore the relationship between vascular dementia and nerve growth factorand brain-derived neurotrophic factor.

目的 探讨血管性痴呆与神经生长因子、脑源性神经营养因子之间的关系。

Objective To gain stable genetic modification of neural stem cells that constitutively secrete brain-derived neurotropic factor and to explore the biological role on the survival and neurite outgrowth of cultured dorsal root ganglion neurons.

目的 建立稳定表达脑源性神经营养因子基因的神经干细胞并观察其对于体外培养的脊髓背根神经节细胞存活及突起生长的影响。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。