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Anatomical study proved:①.4~8 nutritional vessels of sural nerve –small saphenous vein were the intermuscular perforators of peroneal artery, the furthermost one located at(1.0±1.3)cm above the tip of external malleolus with diameter (0.6±0.2)mm;②.2~6 musculocutaneous perforators were given off by the artery of outer head of gastrocnemius muscle to supply nutrition to the sural nerve-small saphenous vein;③.intermuscular perforators from peroneal artery supplied blood to fibula and outer head of soleus muscle.the perforators with an average outer diameter of (1.3-1.6)cm gave off cutaneous branch ,fascial branch and nutritional vessels to the sural nerve-small saphenous vein,which formed the vessel chain of the sural nerve-small saphenous vein ,sub-fascial and suprafascial vessel net.

结果:1、解剖实验证实:①、腓肠神经-小隐静脉营养血管来自腓动脉肌间隔穿支4~8支,最远的跟外侧动脉穿支距外踝尖上(1.0±1.3)cm,外径(0.6±0.2)mm。②、腓肠肌外侧头动脉沿途发2-6支的肌皮穿支营养腓肠神经-小隐静脉。③、腓动脉肌间隔穿支营养腓骨、比目鱼肌外侧半。上述穿皮支平均外径在0.3~1.6mm,发出皮支、筋膜支、腓肠神经-小隐静脉营养血管,形成腓肠神经-小隐静脉血管链以及深、浅筋膜血管网。

The former, intracranially complements patients some factors, most frequently with TH gene to compensate scanty of intrastriatal DA and improve the symptoms of the patients, while have little resistance to the progressive degeneration of dopaminergic neurons; The latter provide variety of neurotrophic factors, most specific being the glial cell-line derived neurotrophic factor , to protect the residual DA neurons in the nigrostriatal system from further pathogenic injuries, while have little benefit to those DA neurons with irreversible damage, and them cannot offset the already-existing symptoms.

前者是给宿主脑内补充某些因子,主要是DA合成过程中的限速酶TH基因,以补充纹状体内DA含量的不足,减轻患者的症状,但对DA能神经元的进行性退变没有治疗效果;后者则是提供各种神经营养因子其中最具特异性的为GDNF,以保护黑质一纹状体系统内剩余的DA能经元免受病因的继续损害但对已发生不可逆性损害的DA能神经元并无拯救作用,无法消除已出现的症状。

Methods Microanatomy and red-and-blue latex injection transpa rency method were applied to study ①The medial antebrachial cutaneous nerve, the lateral antebrachial cutaneous nerve and their nutrient vessels;②The relationship between the basilic vein and MACN and its nutrient vessels; and ③The relationship between the cephalic vein and LACN and its nutrient vess els.

用显微解剖法、标本双色透明法观测前臂内侧皮神经血供、贵要静脉与前臂内侧皮神经及其营养血管的关系和前臂外侧皮神经的血供、头静脉与前臂外侧皮神经及其营养血管的关系。

It has been proved by previous studies that peripheral nerve injury can induce a series of changes of expression of some neural active material and their receptors either in the somata or in the terminals of the damaged primary afferent neurons and motoneurons. These changes may reflect a re-ordering of metabolic priorities so that the synthesis of trophic factors or growth-associated proteins augmented while that of neurotransmitter-related proteins decreased.

以往的研究表明,周围神经损伤能够引起受损神经元(包括初级传入神经元和运动神经元)的胞体或终末内某些神经活性物质及其受体的表达发生一系列变化,其中与神经生长和营养有关的物质常发生上调,而与神经传递有关的物质则发生下调;与此同时,受损神经元的周围常伴随发生胶质反应及神经胶质增生等变化。

Vitamin is a kind of material for alimenting nerves. It helps the nerve cells to grow, and helps to keep the natural functions of nerves. It plays part in the process of forming the nerve deliveries; cure the hearing nerves back to the well-balanced situation.

维生素是营养神经的物质,它不仅能够帮助神经元生长,并且能够帮助维持各种神经的正常功能,参与神经递质的形成,使听力神经恢复正常状态。

there are longitudinal vascular networks interweaved inside and around the great saphenous vein and saphenous nerve on the medial foot .

足内侧大隐静脉—隐神经内部及其周围存在着纵行的血管网,这些血管在营养大隐静脉及隐神经的同时也营养邻近皮肤。

A useful nerve and brain tonic may be prepared as follows: Soak eight dates, a similar quantity of almonds and four cardamoms in a bowl overnight. In the morning remove the skins from the almonds. Reduce the ingredients to a paste, add honey and butter and take with warm milk. This delicious tonic rejuvenates the nervous system quickly.

利于神经和大脑的食物按如下方法来做:将八颗枣、少量的杏仁和四个豌豆浸泡一晚,早上去掉豆皮,把它们制成混合物,加上蜂蜜和黄油,另加一杯热牛奶,这就是美味的快速恢复补充神经系统营养的好食物了。

The therapeutic effect advantages of compound decoctions may be embodied by combining biologic effects of different composition at different links and targets.

相对特异性表现为:清开灵有效组分对Ast活化和对神经营养因子的不同家族、同一家族的不同成员、同一成员的因子及其受体的生物效应的差异性。

MAIN OUTCOME MEASURES: Morphology change of spinal cord was detected by light microscope and electronmicroscope, secreted brain-derived neurotrophic factor was measured by immunohistochemistry and PT-PCR, and the combine behavioral score was used to assess the functional recovery of spinal cord. RESULTS: Immunohistochemistry result showed that OECs transplantation could partly reduce the number of apoptosis cells in spinal gray matter, delay cells reduction in spinal white matter, and accelerate the medullary sheath repair and regeneration.

主要观察指标:应用光学显微镜、电子显微镜观察脊髓形态的变化,采用免疫组织化学、PT-PCR 的方法检测脊髓组织脑源性神经营养因子的分泌,以改良的Gale联合行为评分法对脊髓功能进行评定,结果:免疫组织化学检测显示,嗅鞘细胞移植能部分改善大鼠脊髓灰质神经细胞的凋亡程度,延缓白质神经纤维的减少,促进髓鞘的修复与再生。

Each 1 μL site of spinal cord receiving 109 /L OECs at the speed of 1μL/ min. MAIN OUTCOME MEASURES: Morphology change of spinal cord was detected by light microscope and electronmicroscope, secreted brain-derived neurotrophic factor was measured by immunohistochemistry and PT-PCR, and the combine behavioral score was used to assess the functional recovery of spinal cord. RESULTS: Immunohistochemistry result showed that OECs transplantation could partly reduce the number of apoptosis cells in spinal gray matter, delay cells reduction in spinal white matter, and accelerate the medullary sheath repair and regeneration.

主要观察指标:应用光学显微镜、电子显微镜观察脊髓形态的变化,采用免疫组织化学、PT-PCR 的方法检测脊髓组织脑源性神经营养因子的分泌,以改良的Gale联合行为评分法对脊髓功能进行评定,结果:免疫组织化学检测显示,嗅鞘细胞移植能部分改善大鼠脊髓灰质神经细胞的凋亡程度,延缓白质神经纤维的减少,促进髓鞘的修复与再生。

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