神经萎缩

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease that is familial in 10% of cases.

肌萎缩性侧束硬化症是一种致命的神经退化性疾病，其家族遗传率是10%。

OBJECTIVE: To investigate the humoral immune response pattern for amyotrophic lateral sclerosis patients after neural stem cell transplantation.

目的：研究肌萎缩侧索硬化患者神经干细胞移植后中枢内的体液免疫反应模式。

OBJECTIVE: To investigate the effect of leukaemia inhibitory factor on the activation and differentiation of ENSCs in the brainstem of transgenic mice with amyotrophic lateral sclerosis.

目的：探讨白血病抑制因子对肌萎缩侧索硬化转基因小鼠脑干内源性神经干细胞的激活及分化方向的影响。

Olfactory ensheathing cell transplantation can improve nerve function in amyotrophic lateral sclerosis patients, and delay progressive aggravation of patients' condition.

嗅鞘细胞移植近期能改善肌萎缩侧索硬化患者的神经功能，延缓病情的进行性恶化。

Its characteristic manifestation is myasthenia of limited distal of limb,finger and wrist accompanied with distal amyotrophy,cold rigor and fasciculation when finger extending.The manifastation of electromyogram is harmfulness derived from nerver.

本病青春期发病，特征性表现为：局限性上肢远端、手指及腕无力，伴远端肌肉萎缩、寒冷麻痹和手指伸展时束颤，肌电图表现为神经源性损害。

The acute reaction of neurons against axon repellents is the collapse of growth cones, while the chronical reaction is the change of axon growth direction when they are cocultured with repellents secreting cells.

神经轴突对神经生长排斥因子的急性反应是生长椎的萎缩；将神经元与分泌排斥因子的细胞共同培养时引起的慢性反应是轴突生长方向的改变网。

Their ages ranged 6 to 13 years. Their EEGs were characterized by continuous spike-and-wave discharges during non-rapid eye movement sleep, accounting for 85%-100% of the period of NREM sleep. Clinically, these children had various types of epileptic seizures and exhibited different degrees of neuropsychiatric impairments, language dysfunction, and/or behavioral disturbances. Neuroimaging abnormalities were found in 6 cases, including atelencephalia or atrophy, gray matter heterotopia and leucomalacia. CONCLUSIONS: This study indicates the characteristics of CSWS syndrome in clinical manifestations, EEG and neuroimaging examinations.

结果：9例患儿的视频脑电图结果符合CSWS诊断标准，年龄6~13岁，脑电图表现为棘慢复合波在整个非快速眼动睡眠期几乎持续存在，其放电时间占整个NREM期的85%~100%；临床上患者表现不同类型的癫癎发作，在神经精神方面存在不同程度的损害，存在言语和/或行为障碍；其中6例患儿显示有神经影像学异常，包括脑发育不全或萎缩、灰质异位、脑白质软化等。

In many cases, ephrins act as negative regulators that stimulate growth cone collapse and inhibit neurite outgrowth.

在许多例子中，ephrin对於神经的发育扮演著负向的调控者，它们能够刺激神经生长锥的萎缩而抑制神经纤维的生长。

At the same time, PDI can act as molecular chaperone that help the denatured proteins refold and inhibit the aggregation of the denatured proteins.

在神经变性疾病如帕金森症、阿尔兹海默症、肌萎缩侧索硬化症、多聚谷氨酰胺疾病中，PDI可通过抑制错误折叠蛋白的聚集以及遍在蛋白化，起到神经保护作用。

RESULTS The degenerative changes of nerve ending in Meissner's corpuscles were observed after 1 month of denervation, and the basic structure of the corpuscles had no obvious changes. After 3 months, the axons of corpuscles were disappeared, and the volume of corpuscles was shrunk. The basic structure of nerves was disappeared, and the lemmocyte and neurolemma plate were changed after 5 months.

结果 失神经1个月时触觉小体内的神经末梢已有溃变，触觉小体的基本结构无明显改变；3个月时轴突消失，触觉小体的体积开始萎缩；5个月时神经结构消失，膜细胞及其膜板亦开始改变；8个月时触觉小体内胶原纤维含量逐渐增多；12个月时触觉小体内膜结构与膜间基质完全消失，被胶原纤维代替。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。