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神经膜细胞

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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

ObjectiveTo study a possibility of human amnion membrane as a substratum for culture of calf retinal glial cell .

目的 研究在具有完整基底膜的人羊膜上培养牛视网膜神经胶质细胞的可能性。

Methods : The neural retina was isolated from RPE by enzyme one containing 220u/ml hyaluronidase and 0.1% trypsin, later the RPE cells was isolated from the Bruch"s membrane by enzyme two containing 0.25% trypsin, then the resembled RPE cells was injected into the host"s subretinal space with a special equipment after producing an artificial bleb detachment of neural retina.

用酶Ⅰ(含220u/ml透明质酸酶和0.1%胰蛋白酶)分离视网膜神经上皮层与RPE之间的联系,再用酶Ⅱ(含0.25%胰蛋白酶)将RPE从玻璃膜上分离下来获取悬浮的RPE细胞,用特制的移植针头通过人为造成的局限性视网膜脱离区将其移植入受体视网膜下间隙。

The results showed the ulcer of affected limb healed at 16w after operation in the SIS compound of SCs group, the diameter and appearance of graft is similar to the proximal and distal segment of sciatic nerve without neuroma formation. Plenty of regenerative vascular net was evident on the epineurium.

结果显示,术后16周,SIS复合雪旺细胞组患肢溃疡基本愈合,移植段与近、远坐骨神经直径相当,外观相似,未见神经瘤形成,外膜表面可见丰富的再生血管网。

It was considered an effective and ideal model of PM.2 uPA,PAI-1 and TNF-αwere all involved in the pathogenesis of PM and participated in the process of the degeneration,apoptosis and necrosis of the diseased muscle.3 MMP-9 and TIMP-2 immunoreactivity were positive in the capillary,venous wall,arteriola endotheliocyte and neurilemma in the normal group skeletal muscle,but more intensive in EAM.They may aggravate the pathological changes of the muscle in human PM.

结论1兔纯化的肌球蛋白加含卡介苗的完全弗氏佐剂可仿制出人类多发性肌炎的理想动物模型。2 UPA、PAI-1和TNF-α参与多发性肌炎的肌纤维坏变过程。3 MMP-9和TIMP-2在正常肌肉组织中的毛细血管、静脉管壁、动脉肉皮细胞和神经鞘膜表达,在多发性肌炎中,参与加重肌纤维的坏变过程。

Results there were unconsciousness, respiratory rhythm disturbance and hyporeflexia of pupil light reflex immediately after injury, and reactiveness decrease and activity retardation still existed even after resuming consciousness. at anatomical scene, subarachnoid hemorrhage or cerebroventricular haemorrhage were widespread. at an early stage, there were swelling, collapse, and axonal retraction ball formation at cortico-medulla junction, callosum, brainstem, and cerebellar white matter under microscope. but at the later stage, gitter cell proliferation and nest-like aggregation were major pathophysiological changes at focal brain tissue.

结果 伤后大鼠均即刻出现原发昏迷,其中2只于损伤后20 min内死亡,余持续时间1-30 min不等;伤后大鼠呼吸节律紊乱,瞳孔对光反射减弱或消失,醒后均有程度不等的反应性下降,肢体活动迟缓;肉眼可见广泛蛛网膜下腔出血或脑室出血;光镜下可见皮髓交界区、胼胝体区、脑干、小脑白质等部位的神经轴索有不同程度的肿胀、断裂、轴索球形成,后期有小胶质细胞增生,局部呈巢样聚集。

A nucleus of the tegmentum; it contains the cell bodies of many the neurons that compose the mesotelencephalic dopamine system.

为盖膜的神经核;它包括许多神经元的细胞体,组成 mesotelencephalic 多巴胺系统。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

The result showed that PSexternalization. This observation suggested that apoptotic neurons losed membranephospholipid asymmetry and exposed PS on the outer leaflet of the plasmamembrane. Macrophages then phagocytose apoptotic neurons after specific recognition of theexposed PS.

流式细胞术检测磷脂酰丝氨酸,结果表明凋亡的神经细胞PS外翻,证明AVM可使凋亡的神经细胞膜丧失不对称性,细胞膜中的PS由脂膜内侧翻向外侧,可被吞噬细胞识别后导致凋亡细胞的清除。

AQP3, 7, 8 distribute in a similar manner which is surrounding the membranous labyrihth, including Cortis organ, inner and outer spiral sulcus, stria vascularis, fibrocytes of the spiral ligament and the spiral limbus, saccular and utricular wall, endolymphatic sac and spiral ganglion.

AQP3,7,8三者的分布类似,在螺旋神经节和包绕膜迷路的组织中表达,包括Corti's器、内外螺旋沟、血管纹、螺旋韧带纤维细胞、螺旋缘、椭圆囊壁、球囊壁、内淋巴囊等。

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Lao Qiu is the Chairman of China Qiuyang Translation Group and the head master of the Confucius School. He has committed himself to the research and promotion of the classics of China.

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