神经膜细胞

Glia; gliogenesis; glioma; glial cells; central nervous system; CNS; glial progenitor cells; glial fibrillary acidic protein; ependymocytes; ependoma; cytokeratins; vimentin; tanycytes; ion transport; lining cells; cerebrospinal fluid; CSF; ventricular system; floor plate; axon guidance; choroidal cells; choroid plexus epithelium; Chiari malformations; congenital aqueductal stenosis; neuroblast migration disorders; gap junctions

神经胶质；gliogenesis；神经胶质瘤；胶质细胞；中枢神经系统；CNS；神经胶质祖细胞；胶质原纤维酸性蛋白；室管膜细胞；ependoma；细胞角蛋白；波形蛋白；tanycytes；离子转运；衬细胞；脑脊髓液；CSF；脑室系统；底板；；脉络膜细胞；脉络丛上皮；恰里畸形；先天性导水管狭窄；成神经细胞迁徙扰乱；缺隙连接点

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果：①40只建模大鼠中36只建模成功，建模成功率为90%；②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现，有6只大鼠在3个月后出现白内障，有4只大鼠在喂养接近至6个月时死亡；③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少，减少约61%(P.01)，后极部视网膜明显变薄(P.01)；④电镜观察，视网膜变薄，视杆细胞膜盘紊乱，血管基底膜增厚等表现；⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达，糖尿病组视网膜组织中3个月时可见少量表达，ERK1/ERK2表达部位为神经节细胞层和内核层；6个月时表达强阳性，部位表达不仅见于内核层、神经节细胞层，色素上皮层也见表达。

Methods SH-SY5Y cells, a human neuroblastoma cell line, were incubated with different concentrations of fluoride for 48 hr and somle of them were treated with vitamin E precedently. The functional situation of cells was measured by MTT method; lipid peroxidation was detected by High-Performance Liquid Chromatography; phospholipid was separated by a Silica SepPak cartridge and neutral lipids by HPLC.

体外培养SH-SY5Y人脑神经母细胞瘤细胞，在培养液中加入不同浓度的氟化物或加入抗氧化剂，培养48h后用测定细胞MTT的方法来了解细胞的损伤程度，用高效液相色谱法分离和测定培养液中脂质过氧化物水平，用过柱和比色法测定细胞生物膜磷脂含量，用高效液相色谱法测定细胞生物膜辅酶Q和胆固醇含量。

Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统，对维持中枢神经系统的正常功能非常重要。

ABSTRACT Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统，对维持中枢神经系统的正常功能非常重要。

Result bFGF immunoreactivity was found in neuron and gli al cell in corte x,hippocampus habenular nucleus,and found in macrophage surrounding hematoma; Ln immunoreactivity was found in neurons,glial cells and blood vessles in front a l cortex,hippocampus,thalamus hypothalamus.

结果 脑出血后脑内bFGF主要在扣带皮质、海马、缰核及其他区域表达，阳性细胞骨折主要有神经哮喘元、神经哮喘胶质、吞噬细胞骨折、室管膜细胞骨折、伸长细胞骨折等；Ln不仅在大脑皮质、海马、缰核、下丘脑等区域的神经哮喘元表达，且在这些区域的神经哮喘胶质细胞骨折也表达，血管也有阳性反应。

The cilia of retinal pig merit epithelium disappeared completely by TEM, the granola of retinal pigment epithelium decreased, the rough endoplasmic retinal, the mitochondrial crista breaks, the outer nuclear layer arrangemen disorderin, disc broad, the vacuole timer and outer plexi-form layer shaped, the ganglion cells and membranous of eye cell outer side got think, intermembranous space gotorgancelle disappeared mostly, the crista of cytoplasm ganglion cells layer swelled.

透射电说可见：视网膜色素上皮细胞表面纤毛完全消失，视网膜色素上皮细胞内颗粒减少，粗而内质网、线粒体嵴断裂，外颗粒层细胞排列紊乱，视细胞外段盘膜粗大，盘膜间隙增宽，内外丛状层空泡形成，神经节细胞、细胞器大部分消失，神经节细胞层可见细胞质有嵴性肿胀。

Two types, the myelinated nerve fiber and nonmyelinated nerve fiber, the function of the neuromem

髓神经纤维。神经膜细胞和髓鞘的功能是隔离和绝缘。

Results 5 cases of ependymocytoma, 3 cases of astrocytoma, 1 medulloblastoma hemangioblastoma in 10 cases of intra-medullary tumor; 36 cases of neurogenic tumor, 11 cases of spinal meningioma in 47 cases of subdural extramedullary tumor; 2 cases of neurogenic tumor strided over scleromeninx;2 cases of extradural metastatic tumor, 1 cestodiasis, 2 cases of epidural hematoma, which were mistaken for hemangioma before surgical operation and 1 vascular malformation in 4 cases of intraspinal nontumorous occupying lesion.

结果：10例髓内肿瘤中，室管膜瘤5例；星形细胞瘤3例；血管母细胞瘤1例；成神经管细胞瘤1例。47例脊髓外硬膜下肿瘤中，神经源性肿瘤36例；脊膜瘤11例。2例跨硬膜内外生长的神经源性肿瘤2例。硬膜外的转移瘤2例。4例椎管内非肿瘤性占位性病变中，椎管内绦虫病1例；硬膜外血肿2例，术前误为血管瘤；血管畸形1例。

Results Smad4 genes were expressed throughout the postnatal cochlea of three mouse genotypes at a high level. The expression concentrated in the vascular stria, spiral ligament, basal membrane, tectorial membrane, hair cells, supporting cells and spiral ganglion cells.

结果 Smad4在三种基因型小鼠耳蜗均有广泛表达，表达部位主要集中于血管纹、螺旋韧带、基底膜、盖膜、毛细胞、支持细胞、螺旋神经节细胞等处，其中血管纹和基底膜表达最为明显。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。