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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

Adenosine, a metabolite of adenine nucleotides, is one of the major neuromodulators.

腺苷是腺嘌呤核苷酸的代谢产物,是一种重要的神经调质。

Objective: To study the possibility of neuroendocrine feature of salivary adenoid cystic carcinoma.

目的:探讨涎腺腺样囊性癌具有神经内分泌性的可能性。

Objective:To study the relationship between CXCL12/CXCR4 expression and the neural invasion of salivary adenoid cystic carcinoma.

目的:探讨趋化因子CXCL12及其受体CXCR4与涎腺腺样囊性癌嗜神经侵袭之间的关系。

Adenosine can not only decrease adenosine triphosphate depletion of ischemic tissue, but also has strong neural protective function.

腺苷可减少三磷酸腺苷的耗竭,促进其恢复,并具有神经保护作用。

The group discoered that chemical and mechanical stimuli both resulted in the same messenger molecule, cAMP, which acts like a gatekeeper of reactions in the olfactory neurons.

该小组发现:化学和机械刺激都能导致相同的信使分子――环磷腺苷――产生,环磷腺苷是嗅觉神经反应的关键。

The pituitary gland consisted of neurohypophysis and adenohypophysis. The adenohypophysis was divided into anterior lobe, intermediate lobe and posterior lobe.

黄颡鱼的脑垂体由垂体神经部和垂体腺部组成,垂体腺部又由前叶、间叶和后叶三部分构成。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Pituitary adenylate cyclase activating polypeptide is a widely expressed neuropeptide that has been involved in nerve regeneration, neurone survival and nociception.

垂体腺苷酸环化酶激活多肽是一个广泛表达的神经肽,涉及神经再生,神经生存和伤害感受。

Studies in neuropsychopharmacology and molecular neurobiology indicate that neurotransmitters and its receptors play important roles in alcohol abuse and addiction, and post-receptor signal transduction pathways, including cyclic adenosine 3', 5'-monophosphate-protein kinase A, phosphoinositide, Ca(superscript 2+)-calmodulin, phospholipase D and tyrosine kinase Fyn signaling cascade.

神经精神药理学和神经分子生物学研究表明,酒精滥用和成瘾不仅与中枢神经系统的神经递质及其相关的受体有关,而且,受体后的信号转导通路参与了酒精依赖的形成过程。其中包括环磷酸腺苷-蛋白激酶A、磷脂酰肌醇、Ca(上标 2+)-钙调蛋白、磷脂酶D以及酪氨酸激酶Fyn等信号途径。

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