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Factor of 1 nerve nutrition and lack gene of nutrition of ill nerve of blood-vessel of head of courage and uprightness is a group of special protein and peptide kind element, this are familial include nerve to grow factor (factor of nutrition of nerve of sex of NGF), head source , nerve - 3, alkalescent grow into fiber cell factor and nerve of sex of colloid cell source.

现将几种重要的非炎性细胞因子和缺血性脑血管病关系的探究进展作以下综述。1神经营养因子和缺血性脑血管病神经营养因子是一组非凡的蛋白质和肽类分子,该家族包括神经生长因子、脑源性神经营养因子、神经营养素-3、碱性成纤维细胞生长因子和胶质细胞源性神经营养因子等。

Microglia play an important role in neuroimmunity by participating in the occurrence and development of various nervous system diseases.

小胶质细胞是神经免疫的重要组成部分,参与多种神经疾病的发生发展,也极有可能在干细胞修复神经损伤的过程中扮演重要的角色。

To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray. Of 2300 cDNA clones from low-abundance rat brain cDNA bank, 6 were identified as differentially expressed genes/ESTs in the hippocampus 35 days after lesion, in which none was confirmed by Northern blot. Of 8000 cDNA elements, custom cDNA array identified 47 as differentially expressed genes/ESTs with above 3-fold changes in the hippocampus 35 days after lesion, in which 25 were up-regulated and 22 down-regulated.

中文题名去传入海马的差异表达基因筛选和Cystatin C表达副题名外文题名 Screening of the differentially expressed genes and cystatin C expression in the deafferented hippocampus 论文作者应国新导师周长福研究员学科专业神经生物学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数121页关键词海马星型胶质细胞 Cystatin C 基因表达去神经海马馆藏号BSLW /2003 /Q42 /27 为了阐明中枢神经系统损伤后神经可塑性的分子机制,本实验探索了多种方法,包括传统差异筛库、传统cDNA array和cDNA microarray,对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。

The result showed that, the body wall most outer layer cuticle assumesthe translucent porodine, the surrounding entire body wall; Close isconnected with the cuticle 表皮层 for 合胞体 the structure, inthe back, the abdomen and its two sides separately adds thick to inprominent Cheng Jizhuang, separately contains the back side,腹侧the nerve and compares to the developed back, the abdomen nerve; Themyo- position to the body wall most inner layer, has the muscle cellto arrange becomes; Between the body wall and the digestive tractcavity is a body cavity; Digestive tract for 肌质 structure, afterinference for roundworm's esophagus.

结果显示,体壁最外层的角质层呈半透明的胶状,包围整个体壁;与角质层紧密相连的表皮层为为合胞体构造,在背、腹及其两个侧面分别加厚向内突出成脊状,分别包含背侧、腹侧神经和相比对发达的背、腹神经;肌层位于体壁最内层,有肌细胞排列而成;体壁与消化道之间的空腔为体腔;消化道为肌质结构,经推断为蛔虫的食道。

RESULTS:Immunogold particles for IRE1 could be identified in RGCs of the retin...

IRE1在RGC与少突胶质细胞内胶体金标记颗粒分布部位距离ER管腔距离增加为特征,在钳夹0.5d内神经干少突胶质细胞以及视网膜RGC内均表现非常明显的距离增加。

Morphological features of IND under TEMIn normal neurons, the membrane of cells and nucleus is intact, the cell organs such as mitochondria and endoplasmic reticulum and ribosome are clear, the nucleolus are distinct, the chromatin is loosen, the cytoplasm is filled with neuroendocrine vesicle.

S-100免疫组化结果:神经丛内神经纤维和胶质细胞呈阳性反应,神经元细胞反应呈阴性。IND病变可见巨神经丛内布满大小不一的缺损区,缺损区中央可见发育不良细胞核,神经纤维增生不明显。

Objective To probe into the result of thalamic glioma resection by neuronavigation-guided microneurosurgical treatment.

目的 探讨神经导航下显微神经外科手术治疗丘脑胶质瘤的手术疗效。

Methods The rat MSCs were isolated primarily from the femurs and tibias of the Wistar rats. MSCs were cultured, proliferated and purified by passage culture. After being induced by bFGF, cultuered MSCs were divided into experimental groups (GM1 group, GDNF group and GDNF+ GM1 group) and control group.

取雄性Wistar大鼠股骨和胫骨骨髓,进行MSCs的体外培养、传代扩增及纯化。bFGF预诱导24 h后,依据加入的神经营养因子不同分为单唾液酸四己糖神经节苷脂(GM1)组、胶质源性神经营养因子组和GDNF+GM1组,以及对照组。

After treated in 4% paraformaldehyde,we applied Hematoxylin-Eosin and Nissl staining to exhibit the structure of the retinae and ganglion cells respectively,and also we used immunohistochemical ABC method to display the distribution of GFAP-immunoreactive cells that were specifically classified as the astrocytes.

E 染色以显示视网膜结构,Nissl染色显示神经节细胞,免疫组织化学ABC法染色以显示星形胶质细胞特征性标志物胶质纤维酸性蛋白的阳性反应细胞的分布。

NGF and BDNF reduced differentiation of NSCs into astrocytes, andincreased into oligodendrocytes in co-culture and two-chamber sharedmedium assay.

NGF或BDNF在不同的共培养体系中,可以起到减少神经干细胞向星形胶质细胞分化,增加少突胶质细胞分化的作用,而对神经元的分化没有影响。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

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