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Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统,对维持中枢神经系统的正常功能非常重要。

ABSTRACT Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统,对维持中枢神经系统的正常功能非常重要。

Objective: Chemoresistance is a widespread therapeutic challenge in glial tumors.

目的:在神经胶质肿瘤中,药物抵抗是一种普遍的治疗学的挑战。

Further study indicated that low dose breeding with diphenylene iodonium or apocynin, two inhibitors of NADPH oxidase,significantly suppressed ROS release caused by aerobic exercise.

和H2O2生成均明显增加,而人工饲喂NADPH氧化酶的抑制剂二联苯碘(diphenylene iodonium,DPI)或夹竹桃麻素(apocynin,APO)后,均明显地降低由运动引起的大鼠神经胶质细胞O2^-。

We found that the release of ROS in rat astrocytes was significantly increased by the stimulation of calcium ionophore or opsonized zymosan, which are known to trigger respiration burst in phagocytes by NADPH oxidase pathway. Further study indicated that diphenylene iodonium or apocynin , two inhibitors of NADPH oxidase, significantly suppressed ROS release caused by calcium ionophore or opsonized zvmosan.

我们发现在用吞噬细胞呼吸爆发刺激剂钙离子载体或酵母多糖刺激星形神经胶质细胞时,细胞O〓和H〓O〓产量均明显增加,而NADPH氧化酶的抑制剂二联苯碘(diphenylene iodonium,DPI)或夹竹桃麻素(apocynin,APO)均可以明显地降低刺激剂引起的细胞O〓和H〓O〓产量增加。

Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞(embryonic stem cell , ES cell)体外培养可以分化成为外胚层组织,并进一步分化为神经元和神经胶质细胞。这些细胞已用于中枢神经系统疾病的细胞替代治疗和治疗药物的研发。

Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞(embryonic stem cell , ES cell)体外作育可以剖析成为外胚层结构,并进一步剖析为神经元和神经胶质细胞。这些细胞已用于中枢神经体系疾病的细胞替换治疗和治疗药物的研发。

The glial tissue is where the largest percentage of brain tumors begin.

神经胶质组织是脑癌开始的最大的部分。

The glial tissue is where the largest percentage of brain tumors begin.

神经胶质组织是导致脑瘤的最大的百分比。

The glial tissue is where the largest percentage of brain tumors begin.

这个神经胶质组织是大脑肿瘤生长的最可能的区域。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。