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神经胶质瘤

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Results Postoperative pathological diagnosis showed 13 ependymomas, 2 astrocytomas, 2 oligodendroglioma, 2 lipoma, 1 myeloma, 1 keratose, 1 metastatic tumor, 1 angeioma, and 1 neurinoma.24 cases were treated by surgeon.

结果 病理证实室管膜瘤13例,星形细胞瘤2例,少枝胶质细胞瘤2例,脂肪瘤2例,骨髓瘤、转移瘤、血管瘤、角化物、神经鞘瘤各1例。24例行手术治疗。

I don't think this is clear cell meningioma, chordoma, central neurocytoma, hemangioblastoma, oligodendroglioma, ependymoma or DNET.

我不考虑透明细胞型脑膜瘤、脊索瘤、中枢神经细胞瘤、血管母细胞瘤、少突胶质细胞瘤、室管膜瘤或胚胎发育障碍的神经上皮肿瘤。

In contrast, 11/15 primary glioblastomas contained a significant CD133 subpopulation that displayed neurosphere-like, nonadherent growth and asymmetrical cell divisions yielding cells expressing markers characteristic for all three neural lineages.

相反,15个原代胶质母细胞瘤中有11个含有明显的CD133阳性亚群,呈神经球样,非附着性生长和非对称性细胞分裂,后者产生表达所有三种神经细胞系的特征标志物的细胞。15

This is a retrospective analysis of 194 patients with primary malignant brain tumor, who registered between January 1, 1970 and December 31, 1979 in cancer registration, Cancer Therapy Center, Veterans General Hospital, Taipei, Taiwan, R.O.C. There were 36 cases of glioblastoma multiforme, 86 cases of malignant astrocytoma (grade Ⅲ and a few grade Ⅱ), 22 of medulloblastoma, 12 of oligodendroglioma, 11 of ependymoma or ependymoblastoma and 27 cases of other types. There were 141 male cases with ages ranging from ito 81 years with a mean of 33.3±19.3 and median of 34 years.

自1970年1月至1979年12月台北荣民总医院癌病治疗中心癌病登记组共登记了194例原发恶性脑瘤其中多形神经胶母细胞瘤有36例,第二级及第三级星细胞瘤有86例,神经管胚细胞瘤有22例,间胶质母细胞瘤有12例,室管膜瘤或室管膜胚细胞瘤(ependy-moblastoma)有11例,其他有27例。

About 48%(90/194) were below 29 years of age. Ninety-nine of 194 cases had either radiotherapy alone or supplementary treatment with radiotherapy following surgery. We analyzed multiple prognostic factors. The factors of importance included postoperative radiotherapy; female in glioblastoma multiforme; the primary tumor dose above 5000 rads and/or whole brain irradiation in malignant astrocytoma and glioblastoma multiforme; the primary tumor dose above 4500 rads in ependymoma, medulloblastoma and oligodendroglioma; and spinal axis irradiation above 2000 rads in ependymoma and medulloblastoma that produced a better prognosis than in other groups.

男与女之比例为2.7比1,年龄分布自1至81岁,平均年龄33.3±19.3岁,中值年龄为34岁,29岁以下占48%(90/194),其中99例单独或手术后辅以放射腺治疗,分析同种脑瘤的预后因素,其中多形神经胶母细胞瘤有手术后放射线治疗或女性,多形神经胶母细胞瘤合并星细胞瘤原发肿瘤剂量5000雷得以上或曾全颅腔照射,神经管胚细胞瘤,间胶质母细胞瘤,及室管膜瘤原发肿瘤剂量4500雷得以上,室管膜瘤及神经管胚细胞瘤有脊轴照射2000雷得以上预后均佳,且统计上有显著的差异。

Morphologically similar lesions from 26 patients (mean age, 62 y; range, 46 to 88 y; male/female ratio, 10/16) were retrieved from surgical pathology and consult files. Clinical and endoscopic data were obtained, and immunohistochemistry for S-100 protein, glial fibrillary acidic protein, neurofilament protein, epithelial membrane antigen, claudin-1, CD34, smooth muscle actin, and KIT was performed. The findings were compared with those in mucosal biopsies of 5 submucosal neurofibromas from NF1 patients.

我们从外科病理和档案库里调取了26例病变形态相似的病例(患者平均年龄62岁,范围:46至88岁,男女比例:10/16),得到了他们的临床及内窥镜资料,并给它们都做了S-100蛋白、胶质纤维酸性蛋白、神经丝蛋白、上皮膜抗原、闭合蛋白-1(claudin-1)、CD34、平滑肌肌动蛋白和KIT的免疫组化,所得的结果都与5例NF1患者粘膜下神经纤维瘤的粘膜活检的结果相比较。

objective to investigate and discuss the application of nerve block anesthesia to the resection of brain gliomaous tumour under sober conversation.

目的 探讨应用神经阻滞麻醉在清醒对话中切除脑胶质瘤的价值与安全性。

Methods Nerve block anesthesia was applied to six patients with brain glioma undergoing craniotomy and resection of glioma under the condition of sober conversation.

目的 探讨应用神经阻滞麻醉在清醒对话中切除脑胶质瘤的价值与安全性。

According to the fluorescence real-time quantitative PCR test, EGFR expression amount was higher in glioma cell line spheroids and glioma stem cellular spheroids, but lower in neural stem cellular spheroids, which was consistent with the results of protein level determination.

荧光实时定量PCR检测显示EGFR mRNA在人脑胶质瘤体外细胞系球体及脑肿瘤干细胞球体中表达含量高,在神经干细胞球体中表达含量极低,与芯片中蛋白水平的检测相一致。

The invasive behaviors,which have still been the major problem for neurosurgeons,was demonstrated to be the main reason for failures of current therapeutic strategy of gliomas treatment.it is helpful in therapy of gliomas to improve our understanding of the mechanisms of gliomas progress.

脑胶质瘤的高侵袭性是神经外科医师面临的难题,目前在临床上仍无好的治疗方法,针对侵袭性机制的深入研究可能是其解决途径。

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每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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