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CT contributes to diagnosis of subtentorial neuroglioma in children and offers early diagnosis for the treatment of patients.

CT有助于诊断儿童神经胶质瘤,为临床提供早期诊断。

objectiveto investigate the underlying mechanisms of stcb on the apoptotic induction of human neuroglioma cells.

目的 探讨开口箭皂苷体外对人神经胶质瘤u251细胞的作用和其相关机制。

Among the signals, those of pp-GalNAc-T2 and pp-GalNAc-T9, T13 gene expression are the highest in human gastric cancer cells and neuroglioma cells, respectively.

在胃癌细胞中,pp-GalNAc-T2的信号最为强烈;而在神经胶质瘤细胞中,pp-GalNAc-T9,T13的信号最强。

ObjectiveTo investigate the underlying mechanisms of STCB on the apoptotic induction of human neuroglioma cells.

目的 探讨开口箭皂苷体外对人神经胶质瘤U251细胞的作用和其相关机制。方法开口箭皂苷作用于U251细胞后检测其IC50值。

Key words:Neuroglioma;CT;Children;Subtentorial

关键词]神经胶质瘤;CT;儿童;幕下

ObjectiveTo investigate the underlying mechanisms of STCB on the apoptotic induction of human neuroglioma cells.

作者:蔡晶,雷林生,朱正光,迟德彪目的探讨开口箭皂苷体外对人神经胶质瘤U251细胞的作用和其相关机制。方法开口箭皂苷作用于U251细胞后检测其IC50值。

Curran and a team of American and Canadian researchers, in conjunction with the Philadelphia-based Radiation Therapy Oncology Group, a federally-supported clinical trials organization, found that among 289 patients with either anaplastic oligodendroglioma or anaplastic oligoastrocytoma receiving either a combination of three chemotherapy drugs with radiation or radiation alone, those whose tumors had deletions in chromosome locations 1p and 19q tended to live nearly two and a half times longer than those patients without the missing chromosome portions.

临床癌症杂志》上周报道,卡仑博士和由美国、加拿大研究人员组成的科研小组,联合了总部设在费城的由联邦政府支持的临床实验组织-美国放射肿瘤学协作组,进行了研究。289名病人患有退行性少树突神经胶质瘤或退行性少星细胞瘤,研究发现,这些病人在接受三种化疗药物结合放疗或者只接受放疗后,其中染色体缺乏1p 和19q 的病人比那些不缺乏的病人多存活了2倍半的时间。

PRL-LIR positive perikarya were mainly seen in nucleus suprachiasmaticus, nucleus paraventricularis preopticus, nucleus supraopticus, nucleus hypothalamus paraventricularis, nucleus periventricularis arcuatus and nucleus accumbens. PRL-LIR fibers and their terminals were detected in paleostriatum and median eminence.

结果,PRL阳性胞体主要分布在视交叉上核、视前室旁核、视上核、下丘脑室旁核、弓状核和伏隔核,旧纹状体、正中隆起存在大量阳性纤维末梢,在侧脑室腹侧的室管膜和脑基底神经胶质板上也存在PRL阳性神经元。

Results: The expression of death receptor 5 (DR5) was certificated in U343, DR5 appeared to be located in intracellular perinuclear compartment.

结果:神经胶质瘤细胞株U343表达死亡受体DR5,DR5分布于细胞内细胞核的周围。

Using 11C--PK11195 positron emission tomography, we investigated microglial activation in HD presymptomatic gene carriers, its relationship with striatal neuronal dysfunction measured with 11C-raclopride PET, and the role of PK PET as a possible marker of subclinical disease progression in PGCs. Eleven HD PGCs underwent PK and RAC PET. Their results were compared with those of healthy controls.

利用11C--PK11195电子发射断层扫描,我们研究了HD的基因携带者症状发生前小神经胶质细胞的活化情况,它与纹状体的神经元的机能障碍的关系,以及PET可能作为PGCs亚临床症状进展的指标。11位HDPGCs接受了PK和RACPET检查,其结果与健康对照人群进行比较。

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