神经肉瘤

That consider condyle, bone caruncle of 5 exemple, cartilage fibrosarcoma of 3 exemple, nerve fibroma of 1 exemple, nerve 1. The symptom after 27 patients operation all has different level improvement, live on average without tumour time is 33.5 months. Incontinent companion meets the patient relieve oneself of S1 of 5 operations reservation or above nerve root pubic feeling is lost, after manager cure function trains, 3 parts restore, 2 conserve without progress; bladder and rectum function obstacle all appear after the 12 patients art of root of S2 above nerve, after training via rehabilitation physiotherapy and function, 10 return to normal basically, 2 patients still are put in the obstacle of be convenient to both of different level. 10 withhold S3 or the patient of above nerve root can conserve constrictor function.

结果术后病理报告示：脊索瘤17例、骨巨细胞瘤5例、软骨肉瘤3例、神经纤维肉瘤1例、神经纤维瘤1例。27例患者手术后症状均有不同程度改善，平均无瘤生存时间为33.5月。5例手术保留S1或以上神经根的患者大小便失禁伴会阴部感觉丧失，经理疗功能练习后，3例部分恢复，2例无进展；保全S2以上神经根的12例患者术后均出现膀胱及直肠功能障碍，经康复理疗和功能练习后，10例基本恢复正常，2例患者仍存在不同程度的两便障碍。10例保留S3或以上神经根的患者能保全括约肌功能。

There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum（S1-S2） was involved firstly.There were 56 patients（average,37.7 years） diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma （17）,Ewing′s sarcoma/PNET（14）,multiple myeloma（12）,lymphoma（6） and osteosarcoma（6） were found in 64 patients.

其中脊索瘤95例，男62例，女33例，平均年龄55.7岁，骶尾区疼痛是主要症状（82例），半数以上患者伴有坐骨神经痛，肿瘤多先累及低位骶骨（S3~S5）；神经源性肿瘤76例，男36例，女40例，平均年龄47.7岁，神经纤维瘤43例，神经鞘瘤24例，恶性神经鞘瘤9例，主诉多为坐骨神经痛、会阴部麻木（36例）和无痛性包块（11例），20例患者为查体或其他原因检查时发现，67例骶骨良性神经源性肿瘤起源于S3以上神经者54例，起源于S3以下神经者3例，发生于骶前未累及骶管者10例；骨巨细胞瘤60例，男24例，女36例，平均年龄32岁，腰骶尾部不适（37例）、坐骨神经痛（21例）是主要的临床表现，肿瘤多先累及上位骶骨（S1~S2）；骶骨其他原发良性肿瘤及瘤样病变56例，包括畸胎瘤、皮样囊肿、表皮样囊肿共24例；其他原发恶性肿瘤64例，包括软骨肉瘤17例，尤文肉瘤14例，多发性骨髓瘤12例，成骨肉瘤6例等。

Some of the laryngeal MFH were difficult to be differentiated from carcinosarcoma, pleomorphic rhabdomyosarcoma , myxoid liposarcoma ,malignant neurilemmoma and myxoma without immunohistochemical aids .

喉恶性纤维组织细胞瘤常规组织学与癌肉瘤、多形性横纹肌肉瘤、粘液型脂肪肉瘤、恶性神经鞘瘤、粘液瘤有时易混淆，免疫组织化学有助于明确诊断。

A total of 150 mesenchymal neoplasms of the GI tract, abdominal cavity, and retroperitoneum were retrieved from consult and surgical pathology archives, including 54 GISTs (8 KIT-negative; 13 desmin-positive), 17 GI leiomyosarcomas, 11 GI mural leiomyomas, 13 leiomyomas of the muscularis mucosae, 12 gastric schwannomas, 15 inflammatory myofibroblastic tumors, 9 cases of mesenteric desmoid fibromatosis, 10 dedifferentiated liposarcomas, and 9 malignant peripheral nerve sheath tumors.

我们从会诊病例及活检病例中找出150例间叶性肿瘤（来自胃肠道、腹腔和后腹膜），其中包括54例GISTs（8例KIT阴性、13例desmin阳性）、17例GI道平滑肌肉瘤、11例GI道肌壁间平滑肌瘤、13例GI道粘膜肌层平滑肌瘤、12例胃的神经鞘瘤、15例炎性肌纤维母细胞瘤、9例肠系膜韧带样纤维瘤、10例去分化型脂肪肉瘤和9例恶性外周神经鞘膜瘤。

Results Among the 52 cases, 30 cases were confirmed to fibrosarcomas, which were identical with primary dingnoses;22 cases were revised to malignant fibrous histocytoma (8 cases), malignant nerve sheath tumor (4 cases), monophasic spindle cell synovial sarcoma (3 cases), leiomyosarcoma(3 cases), rhabdomyosarcoma(2 cases) and abdominal desmmoid tumor (2 cases). Of the 18 cases, only two cases were misdiagnosed and were revised to malignant fibrous histocytoma and spindle cell synovial sarcoma, respectively.

结果：1980年前52例中维持原诊断30例，修改诊断22例(42.3%)，分别为恶性纤维组织细胞瘤8例、恶性神经鞘膜瘤4例、单相性梭形细胞滑膜肉瘤3例、平滑肌肉瘤3例、横纹肌肉瘤2例、韧带状纤维瘤2例；1980年后纤维肉瘤18例中，维持原诊断16例，修改诊断2例(11.1%)，分别为恶性纤维组织细胞瘤和滑膜肉瘤各1例。

PPO gene was not detected in the multiple myelome、 malignant fibrous histiocytoma 、malignant lymphoma、malignant neurosarcoma、solitary plasmacytoma of bone、primitive neuroectodermal tumors、lipoma、 osteosarcoma and sarcoenchondroma.

PPO基因在多发性骨髓瘤、恶性纤维组织细胞瘤、恶性淋巴瘤、恶性神经肉瘤、孤立性浆细胞肉瘤、原始神经外胚瘤、脂肪瘤、骨及软骨肉瘤等肿瘤中没有表达。在骨巨细胞瘤中有微弱表达。

No matter what kinds of sarcomatous elements are found in a retroperitoneal dedifferentiated liposarcoma, its clinical behavior is not the same as high grade fibrosarcomas, leiomyosarcomas, osteosarcomas, chondrosarcomas, rhabdomyosarcomas, or MPNST.

无论在腹膜后去分化型脂肪肉瘤中发现何种类型的其他肉瘤成分，它的临床行为都与高级别纤维肉瘤、平滑肌肉瘤、骨肉瘤、软骨肉瘤、或恶性外周神经鞘膜瘤不同。

Fatigue is a widespread symptom in numerous neuroimmunological diseases like multiple sclerosis, myasthenia gravis, morbus Behcet, neurosarcoidosis, neuroborreliosis or immune vasculitis.

疲劳是为数众多的神经免疫疾病如多发性硬化、重症肌无力、贝切特病、神经肉瘤病、神经包柔螺旋体病或免疫性血管炎中的常见症状。

Fatigue is a widespread symptom in numerous neuroimmunological diseases like multiple sclerosis, myasthenia grais, morbus Behcet, neurosarcoidosis, neuroborreliosis or immune asculitis.

疲劳是为数众多的神经免疫疾病如多发性硬化、重症肌无力、贝切特病、神经肉瘤病、神经包柔螺旋体病或免疫性血管炎中的常见症状。

Very rarely, features of high grade osteosarcoma, leiomyosarcoma, chondrosarcoma, rhabdomyosarcoma and malignant peripheral nerve sheath tumor are found.

罕见的情况下可以找见高级别骨肉瘤、平滑肌肉瘤、软骨肉瘤、横纹肌肉瘤和恶性外周神经鞘膜瘤的特征。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。