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神经细胞瘤

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To study the effect of IL-1 on the expression of APP gene in neuronal cell, 80% confluent cultures of human neuroblastoma SH-SY5Y cells were treated with IL-1β.

为研究IL-1对神经细胞中APP基因表达的影响作用,用IL-1β刺激培养至80%融合的人神经母细胞瘤SH-SY5Y细胞。

Glia; gliogenesis; glioma; glial cells; central nervous system; CNS; glial progenitor cells; glial fibrillary acidic protein; ependymocytes; ependoma; cytokeratins; vimentin; tanycytes; ion transport; lining cells; cerebrospinal fluid; CSF; ventricular system; floor plate; axon guidance; choroidal cells; choroid plexus epithelium; Chiari malformations; congenital aqueductal stenosis; neuroblast migration disorders; gap junctions

神经胶质;gliogenesis;神经胶质瘤;胶质细胞;中枢神经系统;CNS;神经胶质祖细胞;胶质原纤维酸性蛋白;室管膜细胞;ependoma;细胞角蛋白;波形蛋白;tanycytes;离子转运;衬细胞;脑脊髓液;CSF;脑室系统;底板;;脉络膜细胞;脉络丛上皮;恰里畸形;先天性导水管狭窄;成神经细胞迁徙扰乱;缺隙连接点

Recombinant apoE〓 protein could inhibit the death of the neurocyte cell of mice brain induced by beta amyloidal peptide 25-35 fragment and the death of the SK-N-SH-neuroblastoma cell induced by beta amyloidal peptide 25-35 fragment and 1-40 fragment.

重组apoE〓蛋白对Aβ 25—35多肽诱导的胎鼠大脑皮质神经细胞凋亡及Aβ25-35和A β1-40多肽诱导的神经成纤维胶质瘤细胞生存力下降均具有明显的拮抗作用,表明apoE对神经退化性疾病中的细胞死亡具有拮抗作用。

Methods By establishing the apoptosis model of primary culture of hippocampal neurons induced by hyperthermia, the dynamic change of concentration Ca(superscript 2+)in hippocampal neurons and the influence to Bcl-2 expression were observed after using chelerythrine chloride which was the special inhibitor of PKC.

通过建立体外高温诱导海马神经细胞原代培养的凋亡模型,应用PKC特异性抑制剂氯化百屈菜红碱,观察海马神经元胞内Ca(上标 2+)浓度的动态变化以及对B淋巴细胞瘤基因2蛋白(Bcl-2)表达的影响。

For the purpose of exploiting the affluent resource of traditional Chinese medicines, rat pheochromocytoma PC 12 cells were used as a model to screen the neuroactive components from natural products. Most of all, the effect of it on inducing the differentiation of PC 12 cells and/or execute the neuroprotective effect challenged by serum-deprivation and oxidative pressure, and its mechanism were studied in this paper.Powered seeds of Cuscuta Chinensis Lam.

本文以利用我国丰富的天然药物资源为目的,用大鼠嗜铬神经瘤细胞PC12作为模型,筛选能模拟NGF的功能诱导PC12细胞分化、对神经细胞有一定保护作用的天然药物,并对其作用机制进行初步探索。

Objective:to study ct features of central neurocytoma in order to improve the diagnosis.methods: ct findings in 6 cases with pathologically-proved central neurocytoma were retrospectively analyzed.

目的:研究中枢神经细胞瘤的ct影像特点,以提高对该病的认识。方法:回顾性分析经手术病理证实的cnc 6例,分析其临床ct表现。

Methods A retrospective review of 11 cases of neurocytoma were operated, including the clinical manifestations, diagnostic modalities and microsurgical outcomes.

回顾总结11例中枢神经细胞瘤的临床表现、诊断方式及显微外科手术治疗效果。

Genetic abnormalities on Chromosome 2p, 10q and l8q may be associated with the pathogenesis of central neurocytoma.

染色体2p、10q和18q的遗传学改变很可能与中枢神经细胞瘤的发病机制有关。

KEY WORDS]neurocytoma;magnetic resonance imaging;diagnosis

关键词]神经细胞瘤;磁共振成像;诊断

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