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Hypoxia induces dedifferentiation of neuroblastoma cells in vivo and in vitro, and under oxygen-compromised conditions the Notch cascade is activated.

在体内和体外缺氧可诱生成神经细胞瘤的去分化,而氧妥协的情况下,Notch信号则被激活。

Neuroblastomas are also associated with increased urinary levels of dopa, dopamine and their metabolites.

神经细胞瘤患者尿中也出现大量的多巴、多巴胺以及它们的代谢物。

Neuroblastomas are also associated with increased urinary levels of dopa, dopamine and their metabolites, particularly homovanillis acid.

神经细胞瘤患者尿中也出现大量的多巴、多巴胺以及它们的代谢物,特别是高香草酸。

In our series, bilateral neuroblastoma was neither associated with familial cases nor with any risk factors.

在我们的患者中,双侧成神经细胞瘤与家族病例和任何风险因素均无关。

Detection of apoptosis in SK-N-MC neuroblastoma cells.

在SK-N-MC神经细胞瘤细胞上观察细胞凋亡。

Results Chromosomal imbalances were demonstrated in 6 cases. Overrepresentation of genetic material was detected in 4 cases on Chromosome 2p and 10q, and 3 cases on Chromosome l8q.

结果 10例中枢神经细胞瘤中,6例发现有染色体的失衡,主要表现为遗传物质在染色体2p(4、10)、10q(4/10)和18q(3/10)上的获得。

This review is focused on involvement of the Notch signaling cascade in the process of differentiation in neuroblastoma cells and normal cells of the sympathetic nervous system.

这篇文章集中于Notch级联信号在交感神经中的成神经细胞瘤分化和正常细胞分化的作用。

It's shown that GIF could not inhibit neuromata extendedly.

表明GIF并不具有广谱的抑制神经细胞瘤株的作用;GIF抑制PC12可能是针对它所具有的胆碱能神经元的某些特性,这一结果对于揭示GIF抑制神经元生长的机制探讨将有所裨益。

Objective To improve the diagnostic level and microsurgical results of the central neurocytoma.

目的: 提高中枢神经细胞瘤的诊疗水平。

Objective To detect the genome-wide genetic alterations in central neurocytoma, and to study the pathogensis of central neurocytoma.

目的 研究中枢神经细胞瘤全基因组的遗传学异常,探讨该肿瘤的发病机制。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力