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Patients with this disease show incoordination of movement because of atrophy of the cerebellum.

此病病人会由於小脑与神经细胞的萎缩、退化产生运动失衡的情形。

A group of specialized nerve cells or a localized mass of gray matter in the brain or spinal cord.

神经核一组专门的神经细胞或存在于大脑或脊髓中灰物质的局部块

In this study, two embryonic cell lines had been induced to study the multifunction of embryonic stem cells. HEC and FEC cells showed pluripotent and differentiation potential in vitro.

HEC和FEC都具有发育上的多能性,在特定的诱导条件下,都可以诱导分化为纤维细胞、肌肉细胞、神经细胞等各种类型的细胞。

The animal model of this method system have, the characteristics of the high fat, high leptin, high Ins, and match with the characteristic of clinical and the pathologic of simple obesity. This studies showed: The acupuncture can obviously reduce the vaule of intaking food and water of the fat rats, and lower the body weight and fat; The acupuncture can urge the diameter, area, physical volume of white fat cell contract, Brown fat tissue of fat rat group surroundings vascular containing large quantity of white fat cell, the acupuncture group was less. this showed: The acupuncture enhanced the white fat cell metabolism, and promotesed the white fat cell to convert to brown fat cell; The frequency of spontaneous electric of nerve cell of pvn of the fat rat is high, the acupuncture counld depress the spontaneous electric of nerve cell of pvn, This showed: the acupuncture can depress the appetite passing to adjust function of pvn nerve; The monoaminergic neurotransmitter of inside of the fat rat brain is disfunction, the acupuncture can rectify this disfunction, and adjust level of 5-HT, and affect appetite, and improve metabolism; The level of leptin and Ins of fat rat increased high, The level of it of acupuncture group decreased, compared with the fat group p.001, This showed: the fat rats have the defeat of leptin and Ins in the body, The acupuncture can lowering this defeat, The level of leptin and Ins of the fat rat in the brain is less than the normal group, The level of leptin of the acupuncture group is high than the fat group, This showed: the acupuncture can increase the transportation of leptin from blood to brain.

本方法所制肥胖大鼠模型具有高体重、高脂、高leptin和高Ins血症的特点,符合人类单纯性肥胖病的临床和病理特征;实验研究显示:针灸能明显减少肥胖大鼠的摄水、摄食量及降低其体重、体脂;针灸能促使白色脂肪细胞直径、面积、体积缩小,减少肥胖大鼠棕色脂肪组织血管周围白色脂肪细胞数量,显示:针灸增强了白色脂肪细胞的代谢,促进了白色脂肪细胞向棕色脂肪细胞的转化:肥胖大鼠PVN神经细胞自发放电频率增加,脑内单胺递质紊乱,针灸通过抑制PVN亢奋的自发放电,调整5-HT水平,达到影响食欲,改善代谢的作用;肥胖大鼠血中leptin及Ins水平增高,与正常组大鼠比有明显差异,提示大鼠体内存在leptin及Ins抵抗,针灸后肥胖大鼠随着体重体脂的下降,血中leptin、Ins水平降低,与肥胖组比均有显著性差异,而针灸后大鼠脑内leptin增加,与肥胖组比P.05,提示:针灸具有改善leptin、Ins抵抗及增加leptin脑内转运的作用。

Affected breeds include the Swedish Lapland Dog, Brittany Spaniel, English Pointer, German Shepherd Dog, Rottweiler, and Cairn Terrier.

由脊髓内神经细胞死亡所致。这种发展型疾病尚无治疗方法,预后不良。

Objective To explore the appropriate method of isolating, purifying and culturing the rat bone marrow mesenchymal stem cells in vitro, and observe the differentiation of MSCs into neuron-like cells induced by noggin gene transfected with adenovi- rus vector.

目的 探讨体外分离、培养大鼠间充质干细胞的方法,采用重组腺病毒介导的noggin基因体外诱导方法,观察 MSCs向神经细胞的定向分化效应。

Objective To investigate whether the tyrosine protein kinase Src and Fyn were involved in the neuronal cell death induced by cerebral ischemia followed by reperfusion.

目的 观察胞内可溶性酪氨酸蛋白激酶Src、Fyn蛋白对脑缺血再灌注后海马CA1区神经细胞存活的影响。

Effects of chronic multiple stress on learning and memory and the expression of Fyn,BDNF,TrkB in the hippocampus of rats[J].

慢性复合应激性学习记忆增强大鼠海马神经细胞增殖和突触后酪氨酸激酶表达的变化[J]。

Both Src and Fyn play an important role in neuronal death induced by cerebral ischemia followed by reperfusion, while Src dominate over Fyn in the process.

胞内可溶性酪氨酸蛋白激酶Src、Fyn蛋白的含量降低对脑缺血再灌注后海马神经细胞有明显保护作用,且以Src作用更为明显。

Results Both Src and Fyn antisense ODNs showed a protective role against neuronal cell death induced by cerebral ischemia/reperfusion. Furthermore, administration of Src antisense ODNs had more protective effect on the neuronal death than Fyn antisense ODNs.

结果 Src、Fyn反义寡核苷酸对脑缺血再灌注后海马CA1神经细胞均有明显保护作用,以Src AS ODNs保护作用更明显,与缺血组比较约有50%细胞存活(P.05)。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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