神经细胞

This region remains highly active, which wears out neurons and alters their connections to each other.

这一区域一直保持高度活跃的状态，使神经细胞受到劳损，而且改变了神经细胞之间的连接线路。

Do you know there is one hundred billion nerve cells in your brain and each cell have kept relationships with each other?

你知道在你的大脑里有1000亿个神经细胞，并且每个神经细胞都和其它细胞有着千丝万缕的连接么？

Did you know that you have one hundred billion nerve cells in your brain, and every nerve cell has many connections to other nerve cells?

你知道在你的大脑里有1000亿个神经细胞，并且每个神经细胞都和其它细胞有着千丝万缕的连接么？

Results By using optical microscope,the neurocytes of hippocampus in experimental group were observed to denaturalize,tumefy,destroy and disappear.And under electron microscope,the karyon was irregular,nucleoles deviated,chondriosome tumefied,crista collapsed,membrane was damaged,substance cavitated.Such changes were more evident with the increased paroxysm of epilepsy,the parameters between control group and operation group had no difference（P＞0.01）.But make a monofactorial variance analysis among cells' number,area,circumference and integral optical density in different groups,it showed that there were significant differences between optional two groups（P.01;at the same time,the more serious injury in hippocampus,the more powerful GFAP immunoreaction was.

结果： 实验组海马区光镜下可见神经细胞变性、肿胀、坏死及神经细胞脱失改变，电镜可见细胞核形态不规则、有切迹、核仁偏位、线粒体肿大、嵴断裂、膜破损和基质空化等改变，随癫痫发作次数增加上述改变越明显，对照组与手术对照组比较，各参数差异无显著性（P＞0.05），将不同组别大鼠细胞数、面积、周长、积分光密度分别作单因素方差分析，不同组别间均差异有显著性（P.01），同时观察到海马区GFAP免疫反应阳性的胶质细胞随海马损伤的加重而GFAP免疫反应增强。

Extraembryonic /ex·tra·em·bry·on·ic/胚外的 adj.Definition : Located outside of the embryonic body. External to the embryo proper, as the extraembryonic coelom or extraembryonic membranes.

部分神经细胞在轴突外围会被一些我们称为髓鞘细胞的细胞包围住，髓鞘细胞可使得神经细胞的冲动传递速度加快，因而形成跳跃式传递。

There was the apoptosis of neurocyte companied the chicken encephalomalacia. The number of apoptosis was affected not only by the content of free radical but also by the function of anti-oxidant system.

在雏鸡发生脑软化的过程中伴有神经细胞凋亡的现象，神经细胞凋亡的数量不仅受体内自由基含量的影响，同时也受到机体抗氧化系统功能的影响。

Result:(1)Tau prevented neurons against Mn toxicity of low and middle concentrations. The ideal conditions can reach upon 4. 5 mM Tau added just, nearly no apoptosis cells could be detected.(2)The percentages of apoptosis intogether were lower than those in Mn just , being concentration-dependent relations with Taurine levels.(3)Mn induced DNA damage of neurons with dose-depedent, The higher of Mn concentration, the lengther of the comet tail and the higher percent comet-like cells. Tau incubated could weaken significantly the lesions of Mn towards DNA on the degree.

结果：(1)牛磺酸对中低剂量锰的毒性有一定的拮抗作用，单独加入牛磺酸效果最好剂量是4.5mM，视野下几乎不见凋亡细胞；(2)牛磺酸干预后培养神经细胞凋亡率低于相同剂量的单纯锰培养细胞组，且与牛磺酸浓度呈剂量依赖性；(3)锰引起培养神经细胞DNA损伤，表现在彗星尾长增加，彗星样细胞百分率增加；加入牛磺酸干预后，可明显改善锰造成的培养神经细胞DNA损伤。

Result Compared to concurrent control groups, neuromotor function are significantly improved in 1h and 6h experiment group. The indexes of neural cell apoptosis decreased significantly (P 0.01). But in 24h experiment group, the decrease of the index are not statistically significant. Conclusion Early application of rhEPO could lessen the lesion of neuromotor function. The protection is partially due to the reduction of neural cell apoptosis.

结果：与对照组相比，脊髓损伤后促红细胞生成素1小时，6小时实验组神经运动功能明显改善，脊髓神经细胞凋亡指数均明显下降(P 0.01)；而术后24小时组与对照组相比，脊髓神经细胞凋亡指数的下降无统计学意义结论：早期应用外源性EPO对脊髓不完全损伤后引起的神经运动功能损害具有保护作用，此种保护作用可能与EPO能够减少神经细胞凋亡有关。

Moreover, we established the model of apoptosis induced by corticosterone and explored the effect of gangliosides, which is a active component in pilous antler, on this apoptotic cell model. The effects of gangliosides on neurotransmitter release, neuronal filopodia formation, calcium signal cascade and 5-HTl A receptor-ligand competitive binding were also studied. 2. Theory study: The viewpoint on brain and kidney in traditional Chinese medicine and that in Western medicine were comparatively studied. The essence of the relationship between kidney and brain in traditional Chinese medicine Subsequently, in combination with the analysis on the results in the empirical study, we discussed the essence of the relationship between kidney and brain in traditional Chinese medicine from the viewpoint about the feedback mechanism of hippocampus-hypothalamic-pituitary-adrenal.

体外实验采用糖皮质激素建立神经细胞凋亡模型，研究鹿茸有效成分的干预作用，并从神经递质释放、神经细胞丝状伪足生成、神经细胞钙信号途径、5-HT_(1A)受体配体竞争结合等方面进行机制探讨。2、理论研究：比较中西医学对肾和脑的传统认识以及现代研究，分析中医学中肾和脑的现代科学内涵，结合实验研究结果，从现代生物学海马—下丘脑—垂体—肾上腺轴负反馈机制的角度对中医肾脑相关理论的实质进行探讨。

Objective To study the protective effects of imipramine on glutamate-induced neurotoxicity in cultured rat cerebral cortical neurons.Methods Cortical neurons of fetal of rat were cultured in vitro.The protective effects of Imi on glutamate-induced neurotoxicity were obserced.

目的 研究米帕明对谷氨酸损伤培养鼠皮层神经细胞的保护作用方法分离培养15～18 d胎龄的大鼠神经细胞，加入谷氨酸，观察谷氨酸对神经细胞的损伤作用及米帕明的保护作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。