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Objective:To identify chronologic changes in the histomorphometry and structure of the chronically denervated posterior cricoarytenoid muscle.

目的:动态地观察单侧喉返神经切断后,健侧环杓后肌酶组织化学和结构的改变。

At three months, the latency and wave amplitude of regenerating nerve were 2.74 0.49msx 19.02 2.32mv respectivly in group A, and 2.32 0.46ms, 21.04 1.09mv respectively in group B, there was no statistical difference in both groups, no regenerating nerves were found to bridge the gaps and cicatrices formed, the results could not be acquired.

肌电图测量及分析术后2月电生理检测再生神经的潜伏期及波幅,A组分别为3.37±0.54ms、13.82±1.73mv,B组分别为2.82±0.49ms、17.45±1.51mv,A组低于B组(p<0.05),3个月时A组潜伏期及波幅分别为2.74±0.49ms、19.02±2.32mv,B组分别为2.32±0.46ms、21.04±1.09mv,A、B两组无显著性差异(P>0.05)。C组仅见瘢痕组织,无神经纤维再生连接缺损处,无法进行检测。3。

Methods The procedure used autologous disc of the rats from the coccygeal intervertebral discs to impose direct pressure to the L5 dorsal root to induce an animal model of lumbar disc herniation. After the epidural tube was inserted, early prophylactic therapy and late remedial dexamethasone therapy were conducted to observed the PWMT of both hind paws of the rats.

取大鼠自体尾部椎间盘组织置于L5神经根下,建立椎间盘突出动物模型,然后硬膜外置管,采用早期预防性给药及晚期治疗性给药方法,观察地塞米松对大鼠后足底机械刺激疼痛阈值的影响。

Objective To report the clinic result of bone and skin defects of forefoot and defects of forefoot treated by allograft and complex flap of crural artery with nerve and periosteum.

目的报道应用同种异体骨移植带骨膜和神经的小腿动脉复合组织瓣修复前足骨和皮肤缺损以及前足再造的临床应用效果。

Mehtods Thirty male SpragueDawley rats were randomly divided into acute stress,chronic stress and control group(each n=10),acute and chronic stress models were made with forced swimming and empty bottle stimulation separately,and frequency of getting into central grille, detention time , outer grille numbers,modifying numbers and dejecture grain number were observed with openfield experimental box;expressions of neuropeptide Y and adenylcyclase in prefrontal lobe cortex, hippocampus CA3,striatum of the groups were observed using the immunohistochemistry method and correlation analyses conducted.

将30只雄性SD大鼠随机分为急性应激组、慢性应激组和正常对照组,每组10只,用强迫游泳和空瓶刺激分别制作急性和慢性应激模型,采用开野实验箱观察各组大鼠进入中央格次数、停留时间、外周格子数、修饰次数、粪便粒数;采用免疫组织化学方法检测各组大鼠神经肽Y、腺苷酸环化酶在前额叶皮质,海马CA3区,纹状体的表达水平,并进行相关分析。

Mehtods Thirty male Sprague??Dawley rats were randomly divided into acute stress,chronic stress and control group(each n=10),acute and chronic stress models were made with forced swimming and empty bottle stimulation separately,and frequency of getting into central grille, detention time , outer grille numbers,modifying numbers and dejecture grain number were observed with open??field experimental box;expressions of neuropeptide Y and adenylcyclase in prefrontal lobe cortex, hippocampus CA3,striatum of the groups were observed using the immunohistochemistry method and correlation analyses conducted.

将30只雄性SD大鼠随机分为急性应激组、慢性应激组和正常对照组,每组10只,用强迫游泳和空瓶刺激分别制作急性和慢性应激模型,采用开野实验箱观察各组大鼠进入中央格次数、停留时间、外周格子数、修饰次数、粪便粒数;采用免疫组织化学方法检测各组大鼠神经肽Y、腺苷酸环化酶在前额叶皮质,海马CA3区,纹状体的表达水平,并进行相关分析。

Wounds such as road accidents, gunshot injuries, fire burns and some internal medicine diseases like diabetes, tumors and palsies always accompany with muscle injuries. Muscle regeneration is relatively difficult on the conditions of serious and large area of muscle injury or loss. Finally the raw surface will be replaced by fibrous connective tissue and form scar, which may disenable the movement of body and badly influence nerves and blood-vascular system, and eventually develop into obduracy wound.

各种创伤如车祸伤、枪弹伤、烧伤及部份内科疾病如糖尿病、肿瘤和瘫痪所致的肢体坏疽都常伴肌组织损伤,对于严重或面积较大的肌损伤或缺损,肌肉的再生相对困难,创面最终被纤维结缔组织替代而形成瘢痕,导致机体运动功能障碍并累及神经、血管系统,影响患者的预后和生活质量。

Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞(embryonic stem cell , ES cell)体外培养可以分化成为外胚层组织,并进一步分化为神经元和神经胶质细胞。这些细胞已用于中枢神经系统疾病的细胞替代治疗和治疗药物的研发。

Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞定向分化为神经细胞的研究进展小鼠胚胎干细胞(embryonic stem cell , ES cell)体外培养可以分化成为外胚层组织,并进一步分化为神经元和神经胶质细胞。

Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞(embryonic stem cell , ES cell)体外培养可以分化成为外胚层组织,并进一步分化为神经元和神经胶质细胞。这些细胞已用于中枢神经系统疾病细胞替代治疗和治疗药物研发。

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The split between the two groups can hardly be papered over.

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