神经组织

The typical pathological characteristics of SPTs may result from gradual degenerative changes induced anoxemia in some SPT's areas. The heterogeneity of SPTs on different antibody markers showed that the SPTs may be originated from pancreatic embryonic stem cells, and result from immature differentiation of the pluripotential stem cells during pancreatic genesis.

SPT典型病理特征是由于肿瘤组织不同区域相对缺血、缺氧所造成的退行性变的结果，SPT表达多种组织来源的抗原，反映其可能来源于胰腺干细胞及与其发育密切相关的胚胎神经嵴的神经前体细胞，且在发育过程中发生分化不成熟的结果。

Results: The numbers of Bombesin positive pulmonary cells, the lamina propria S-l00 protein, neuron-specific enolase positive nerve fibers, IgE positive cells, mast cells and IgE positive mast cells significantly increased in bronchiectasis. The changes of pulmonary endocrine cells, nerve fibers and IgE positive cells were more significantly in hyperplastic BALT areas. The S-100 and NSE were found in lymphoid tissue and BALT. A close contact was found between mast cells and the S-100 positive nerve fibers. An IgE positive outer zone was found on MC surface. Mast cells and IgE positive cells were seen in the bronchial epithelium and alveolar septa.

结果：支气管扩张症中，支气管上皮蛙皮素阳性细胞、固有膜S-100蛋白和神经特异性烯醇化酶阳性神经纤维、IgE阳性细胞、MC和IgE阳性MC均显著增多，且在支气管相关淋巴组织增生的区域上述肺内分泌细胞、神经纤维和IgE阳性细胞增多尤为显著，S-100蛋白和NSE阳性神经纤维分布於弥散淋巴组织和BALT中，MC与S-100蛋白阳性神经纤维紧密接触，MC表面有IgE阳性环状带，MC和IgE阳性细胞出现在支气管上皮间和肺泡壁。

The nerve need not be present throughout the entire period of regeneration; once the limb has begun to grow and tissues are sufficiently differentiated, the nerve may be removed without impariment of the morphegenetic potency acquired by these tissues during their earliest stage of formation. Singer (1974) has shown that it does not matter for regeneration what type of nerve, whether motor, sensory, or autonomic, is present in the blastema.

但是再生的肋骨市是「不完全发育」，神经不会在整个再生过程中呈现出来；一旦，肋骨开始生长，而且组织得到足够的养分，神经就可以从器官器官再生的部位移除，力量，是细胞在早期形成的时间得到的Singer，则证明了：任何细胞组织，对再生来说，是不相关的，不管是运动、感觉、自动的，都在胚芽中呈现。

The neural stem cells can be isolated from human embryonic cerebral tissue . The ratio of cell clone formation from smaller gestational age is higher than that from elder gestational age .The differentiation of neural stem cells from hindbrain is easier than that from forebrain.

从人胚脑组织的前、后脑中分离出神经干细胞；较小胚龄的脑组织原代培养时细胞克隆的形成比例较高；后脑组织分离的南京医科大学硕士学位论文神经干细胞比前脑组织来源的更容易分化。

To investigate the possibility of neuronal PC12 cells being used as models to investigate the innervation of tissue-engineered cardiac tissue.

探索神经生长因子诱导的交感神经元样PC12细胞作为组织工程化心肌组织神经支配研究模型的可行性。

It was conferred that neuroglia cells restrained the apoptosis of target tissue,and then afforded the probability to nerve regenerated to target issue.

推测可能是由于神经胶质细胞的作用，提前抑制了靶组织的细胞凋亡，从而为神经再生回靶组织提供条件。

We suppose that there is a presently undefined subfraction of stem cell population that exists in a number of tissues beyond embryonic development. We term them postembryonic pluripotent stem cells. They differ from embryonic stem cells in that they gradually lose some differentiation potentials during development and adopt some special phenotypes once within a certain tissue. They can give rise to different kinds of stem cells; therefore, help to maintain balance during development and metabolism. They provide cells not only for the damaged tissues they reside, but also for damaged tissues different from them by migration triggered by proinflammatory cytokines or growth factors.

我们认为在胚胎发育后的多种组织中都存在一类原始干细胞群体，它们和造血干细胞、神经干细胞等多能干细胞不同，后者只能分化为特定胚层的细胞，而这类原始干细胞可分化为不同胚层的组织细胞；另一方面，它们区别于胚胎干细胞，在妊娠期间会逐渐失去部分分化潜能，并且会出现一些特殊表型或者分子标志，我们称其为胚胎后亚全能干细胞，这类干细胞具有下列特性：可分化为不同胚层的细胞，分布于身体的所有组织和器官，具有相同的表型或标志；他们在胚胎期存在于一些或全部的组织和器官中，可分化为不同类型的多能干细胞并在生长发育和新陈代谢中维持这些多能干细胞保持平衡；可以参与机体自我修复和更新，不仅能分化为所在器官的组织特异性细胞，参与器官重塑，也可以在炎症因子或者生长因子的趋化作用下，远处转移修复受损组织。

In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上，为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现，本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点，分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点；其次，糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降，这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足，继发伤口难愈？

It is widely known that during the development of nervous system, the synapse between neurons and target tissues plays an important role in the survival and maturation of neurons because target tissues or target cells can produce and secrete many kinds of neurotrophic factors and neuroinductive factors which can promote the growth, differentiation and migration of innervating neurons.

在神经系统发育中，神经元与相应靶组织建立的突触联系，是神经元存活和分化的关键因素，因为靶组织或靶细胞可以合成、分泌多种神经营养因子和神经诱向因子，促进支配神经元的生长、分化和迁移。

Methods 12 patients with soft tissues defects around the foot of the diabetes were repaired by musculocutaneous,neurocutaneous axial island flaps transfer which included 4 cases of femoral forelateral flap,1 case of latissimus dorsi muscular flap,1 case of tensor fascia lata musculocutaneous flap,3 case of island flaps based on the sural nerve,1 case of island flaps based on the peroneus superficialis nerve and 2 cases of medial crural faee flap.

目的 探讨皮瓣移植修复糖尿病足组织缺损的临床效果方法采用股外侧皮瓣4例，背阔肌皮瓣1例，阔筋膜张肌皮瓣1例游离移植，腓肠神经营养血管蒂岛状皮瓣逆行转位3例，腓浅神经营养血管蒂岛状皮瓣逆行转位1例，小腿内侧皮瓣2例逆行移植修复糖尿病足组织缺损创面12例。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了