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Results:① Neuroglobin-immunocreactive positive cells were detected in cortex, thalamencephalon, hippocampus, hypothalamus, cerebellum, brain stem and spinal cord;② Ngb-IR positive nerve cells were also detected in peripheral nervous system such as intramural ganglia, myelinated nerve fiber and retina;?Substantial Ngb protein expression was also found in metabolically active endocrine tissues such as the pituitary gland , adrenal gland and testis.?

结果:(1)在所观察的大脑皮质、海马、丘脑、下丘脑、脑干、小脑和脊髓神经细胞都出现Ngb蛋白免疫阳性反应,不同区域表达强度不同:(2)在外周神经系统的神经节、有髓神经纤维和视网膜也观察到Ngb免疫阳性反应;(3)垂体、肾上腺、睾丸也可见到Ngb-IR阳性细胞。

These NFL and fundoscopic findings suggest that some of the injury seen in NMO may be vascularly mediated.

与多发性硬化患者相比,视神经脊髓炎患者的神经纤维层轴索损伤程度更严重和广泛。

Fig.1 Injection site at the left ventrolateral area of the brain stem in rat.

图2 大鼠翼腭研究神经节内,顺行追踪的粗阳性研究神经纤维及其终末

Fig.1 Injection site at the left ventrolateral area of the brain stem in rat.

图2 大鼠翼腭神经节内,顺行追踪的粗阳性神经纤维及其终末

Results Wallerian degeneration in the distal nerve happened at weeks right after cush. Nerve regeneration was seen at 2 weeks.

结果:钳夹后1周损伤处远段神经发生华勒变性,钳夹后2周神经纤维开始再生。

DTI is more accurate than Mifi in diagnosing Wallerian degeneration.

DTI技术通过测量FA值及其比值及神经纤维束的三维重建,较常规MRI更为准确客观地诊断Wallerian变性。

Results: Dynamic observation with histopathology and immunohistochemical staining showed that, after the nerve root nerve root compression, the myelinated nerve fibers decreased and there was ultrastructure changes of the nerve fibers, such as Schwann cell cytoplasm swelling and edema, Wallerian degeneration, and demyelinated degeneration of axons.

结果:通过对压迫神经根及神经根节大体观,组织病理学和免疫组织化学的光学显微镜的动态观察,可见神经根压迫后其有随神经纤维数目减少和超微结构的改变,如神经模细胞胞质肿胀和细胞水肿、华勒变性、神经轴突脱髓鞘变等。

However, since fibres from these areas are projected forward into the cerebral cortex where the primary transmitter is acet ylcholine, attention has focussed on the management of this mediator in the searc h for appropriate therapeutic agents.

一些尝试关注和集中于其他的一些媒介的功能,比如作为中脑部媒介的5-hydroxytryptami ne,但是因为这些区域中的神经纤维投射向乙酰胆碱在其中起主要作用的神经皮层,关注焦点就转向寻找具有适当疗效物质来治疗和控制该类媒介。

Contact with the receptors depolarizes nerve fibers and starts an electric signal moving down the auditory nerve toward the brain.

与感受器的接触会使神经纤维退极化,产生一个电讯号,沿着神经传入大脑。

Depletion of this neuropeptide thus desensitizes the nerve fiber.

因此枯竭的神经肽能钝化神经纤维,使其不敏感。

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