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In terms of expression site, synaptic plasticity can be divided into presynaptic and postsynaptic.

突触前可塑性是指通过对神经递质释放过程的干预、修饰,调节突触强度的过程。

Alpha-Synuclein is a presynaptic nerve terminal protein of unknown function, although several studies suggest it is important for synaptic plasticity and maintenance.

A-synuclein是一未知功能的突触前的神经末端蛋白,即使许多研究提出它对于突触可塑性和维持非常重要。

Flies increase sleep both after exposure to an enriched social environment and after protocols that induce long-term memory. We found that flies mutant for rutabaga, period, and blistered were deficient for experience-dependent increases in sleep.

研究人员称,神经学家们认为,形成新的神经元突触是大脑进行记忆和学习的一种重要途径,但由于头颅空间有限等原因,大脑不能无限制地增加神经元突触。

Concentrations of DA and 5-HT in different regions were measured by high performance liquid chromatography; the expression of SERTmRNA was detected by in situ hybridization; the degeneration of neuron and terminal was demonstrated by Bielschowsky and Glee Marsland silver staining; and the protein expression of GFAP was detected by immunohistochemistry.

2采用高效液相色谱法测定不同脑区神经递质DA和5-HT的含量;采用原位杂交方法检测SERTmRNA;Bielschowsky及Glee Marsland氏改良银浸染法显示神经元胞体、树突和轴突;免疫组织化学方法检测GFAP的表达。

Results The crosssectional images of the CVH and MRI images fairly could display the uncinate process and it's adjacent structures.

选取5例中国数字化可视人体数据集中C3~C7椎体上缘清楚显示钩突的薄层断面图像,观察并测量钩突与邻近的椎动脉和颈神经的位置关系,选择对应平面的MRI断面图像对照分析。

Methods Crosssectional images from the superior border of the 3rd to the 7th cervical vertebrae were selected from the 5 data set of the Chinese visible human. The uncinate processes, vertebral arteries and cervical nerves were observed and measured. The thin slices were compared with the corresponding MR images on the axial planes.

选取5例中国数字化可视人体数据集中C3~C7椎体上缘清楚显示钩突的薄层断面图像,观察并测量钩突与邻近的椎动脉和颈神经的位置关系,选择对应平面的MRI断面图像对照分析。

Sectional images from the superior border of the 3rd to the 7th cervical vertebrae were selected from the 5 data set of the Chinese visible human. The uncinate processes, vertebral arteries and cervical nerves were observed and measured. The thin slices were compared with the corresponding MR images on the axial planes.

选取5例中国数字化可视人体数据集中C3~C7椎体上缘清楚显示钩突的薄层断面图像,观察并测量钩突与邻近的椎动脉和颈神经的位置关系,选择对应平面的MRI断面图像对照分析。

The retinal nerve fibre layer is composed largely of unmyelinated axons of retinal ganglion cells, and is accessible to study with optical coherence tomography, giving a measure of axonal loss.

视网膜神经纤维层大致由视网膜神经节细胞的无髓轴突组成,并且可以用视觉相干X线断层扫描的方法来研究,可测定轴突的缺失。

Radiolabeled pharmacological binding assay showed: 1 BmK AS bound specifically to a single class of non-interacting binding sites on both rat brain and cockroach nerve cord synaptosomes with high affinity and low low capacity. The association of BmK AS with both synaptosomes was quick to reach equilibrium, but the dissociation seemed to be only partial. The specific binding of BmK AS was independent of membrane potential, and couldn't be modified by veratridine. Moreover, the binding of BmK AS could be inhibited by native BmK AS, BmK AS1, BmK IT2 and BmK IT on both synaptosomes, but not or partially inhibited by BmK Ⅰ and suggesting BmK AS type neurotoxins might bind to a distinct receptor site on mammal and insect sodium channels with a similar manner from β-scorpion toxins.

二。蝎毒素多肽配体与哺乳动物和昆虫靶离子通道受体的药理结合特性及其靶结合位点的研究:经放射性标记结合和竞争抑制实验表明:1)BmK AS在大鼠脑和蟑螂神经索突触体上有单一非协同性高亲和力低结合容量结合位点,能快速结合并达到平衡,但仅能部分解离,其结合不依赖于膜电位,也不受藜芦碱调节,天然的BmK AS,BmK AS-1,BmK IT2和BmK IT可抑制〓AS与两种突触体的特异结合,而BmK Ⅰ无或仅有部分抑制效应。

Injection of wild-type or mutated agrin into rat soleus muscle induced the formation of nonsynaptic acetylcholine receptor clusters, but the mutant protein specifically destabilized the endogenous neuromuscular junctions.

注射野生型或突变型集聚蛋白到大鼠比目鱼肌中,诱导非突触性乙酰胆碱受体簇的形成,但突变的蛋白破坏了内源性神经肌肉接头的稳定性。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

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