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神经瘤

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That consider condyle, bone caruncle of 5 exemple, cartilage fibrosarcoma of 3 exemple, nerve fibroma of 1 exemple, nerve 1. The symptom after 27 patients operation all has different level improvement, live on average without tumour time is 33.5 months. Incontinent companion meets the patient relieve oneself of S1 of 5 operations reservation or above nerve root pubic feeling is lost, after manager cure function trains, 3 parts restore, 2 conserve without progress; bladder and rectum function obstacle all appear after the 12 patients art of root of S2 above nerve, after training via rehabilitation physiotherapy and function, 10 return to normal basically, 2 patients still are put in the obstacle of be convenient to both of different level. 10 withhold S3 or the patient of above nerve root can conserve constrictor function.

结果术后病理报告示:脊索瘤17例、骨巨细胞瘤5例、软骨肉瘤3例、神经纤维肉瘤1例、神经纤维瘤1例。27例患者手术后症状均有不同程度改善,平均无瘤生存时间为33.5月。5例手术保留S1或以上神经根的患者大小便失禁伴会阴部感觉丧失,经理疗功能练习后,3例部分恢复,2例无进展;保全S2以上神经根的12例患者术后均出现膀胱及直肠功能障碍,经康复理疗和功能练习后,10例基本恢复正常,2例患者仍存在不同程度的两便障碍。10例保留S3或以上神经根的患者能保全括约肌功能。

These diseases included enormous schwannoma caused by intercostal neuve,ancomplete type neourofibramatosis,enormous ganglioneuroma in sacrococcyx,A skin tumor of chest wall and enormous retroperitoneal extradural cyst.

包括源于肋间神经巨大神经鞘瘤、不完全型神经纤维瘤病、骶尾部巨大神经节细胞瘤、胸壁 Askin瘤和腹膜后巨大的硬脊膜外囊肿,着重对其 X线诊断进行探讨。

The pcDNA〓-apoE〓 plasmid was transfected to SK-N-SH Neuroblastoma cell by liposome. It could be screened by G〓. The immunohistochemical assay was shown that neuroblastoma cell transfected by pcDNA〓-apoE〓 expressed the recombinant apoE protein. The intracellular expressed recombinant protein could inhibit the death of neuroblastoma cell induced by beta amyloidal peptides 25-35 fragment.

用pcDNA〓—apoE〓真核表达载体与脂质体共转染神经成纤维胶质瘤细胞,用G〓选择压力筛选,细胞免疫荧光检测表明,pcDNA〓—apoE〓转染的神经成纤维胶质瘤细胞表达了apoE〓重组蛋白,这种内源性的apoE〓重组蛋白对25μM Aβ25—35多肽诱导的神经成纤维胶质瘤细胞的死亡具有拮抗作用。

None of the GISTs, desmoid tumors, inflammatory myofibroblastic tumors, schwannomas, dedifferentiated liposarcomas, or malignant peripheral nerve sheath tumors showed cytoplasmic reactivity for smoothelin.

所有GISTs、韧带样纤维瘤、炎性肌纤维母细胞瘤、神经鞘瘤、去分化脂肪肉瘤和恶性外周神经鞘膜瘤病例的瘤细胞浆均不表达smoothelin。

Of 23 adrenal tumors, 4 cases were adrenocotical adenoma, 10 cases were pheochromocytoma; adrenocortical carcinoma, metastatic carcinoma, ganglioneuroma and adrenal myelolipma were 2 cases respectively, schwannoma was only 1 case.

本组23例肾上腺肿瘤中,皮质腺瘤4例,嗜铬细胞瘤10例,肾上腺皮质癌、转移瘤、神经节细胞瘤、髓样脂肪瘤各2例,神经鞘瘤1例。

The term composite pheochromocytoma has been used for pheochromocytomas with a component of neuroblastoma, ganglioneuroblastoma, ganglioneuroma, or malignant peripheral nere sheath tumor.

复合嗜铬细胞瘤主要是指具有成神经细胞瘤、成神经节细胞瘤、神经节瘤或恶性周围神经鞘膜瘤成分的嗜铬细胞瘤。

Results: the findings on ct and mri were as follows: 57 cases of oligodendroglioma, 15 cases of ganglioglioma , 5 cases of dysembryoplastic neuroepithelial tumor , 3 cases of pleomorphic xanthoastrocytoma .conclusion:the images on ct and mri of cerebra peripheral tumor occur some characters , so ct and mri were certain worth on the diagnose and differentiate diagnose of cerebra peripheral tumor.

结果:少枝胶质瘤47例,间变性少枝胶质瘤10例,节细胞胶质瘤15例,胚胎发育不良性神经上皮瘤5例,多形黄色细胞瘤3例。结论:脑浅表肿瘤存在影像特征,ct及mri对其诊断有一定的价值。少枝胶质细胞瘤;节细胞肿瘤;胚胎发育不良性神经上皮瘤;多形性黄色星形细胞瘤;ct;mri

This is a retrospective analysis of 194 patients with primary malignant brain tumor, who registered between January 1, 1970 and December 31, 1979 in cancer registration, Cancer Therapy Center, Veterans General Hospital, Taipei, Taiwan, R.O.C. There were 36 cases of glioblastoma multiforme, 86 cases of malignant astrocytoma (grade Ⅲ and a few grade Ⅱ), 22 of medulloblastoma, 12 of oligodendroglioma, 11 of ependymoma or ependymoblastoma and 27 cases of other types. There were 141 male cases with ages ranging from ito 81 years with a mean of 33.3±19.3 and median of 34 years.

自1970年1月至1979年12月台北荣民总医院癌病治疗中心癌病登记组共登记了194例原发恶性脑瘤其中多形神经胶母细胞瘤有36例,第二级及第三级星细胞瘤有86例,神经管胚细胞瘤有22例,间胶质母细胞瘤有12例,室管膜瘤或室管膜胚细胞瘤(ependy-moblastoma)有11例,其他有27例。

Results 5 cases of ependymocytoma, 3 cases of astrocytoma, 1 medulloblastoma hemangioblastoma in 10 cases of intra-medullary tumor; 36 cases of neurogenic tumor, 11 cases of spinal meningioma in 47 cases of subdural extramedullary tumor; 2 cases of neurogenic tumor strided over scleromeninx;2 cases of extradural metastatic tumor, 1 cestodiasis, 2 cases of epidural hematoma, which were mistaken for hemangioma before surgical operation and 1 vascular malformation in 4 cases of intraspinal nontumorous occupying lesion.

结果:10例髓内肿瘤中,室管膜瘤5例;星形细胞瘤3例;血管母细胞瘤1例;成神经管细胞瘤1例。47例脊髓外硬膜下肿瘤中,神经源性肿瘤36例;脊膜瘤11例。2例跨硬膜内外生长的神经源性肿瘤2例。硬膜外的转移瘤2例。4例椎管内非肿瘤性占位性病变中,椎管内绦虫病1例;硬膜外血肿2例,术前误为血管瘤;血管畸形1例。

Neural stem cells have a strong self-renew mechanism and it can transform after a little break. Neural stem cells have a long term survival, which mean that it has more probability of wrong copy than mature cells. These cells are formed glioma stem cells in the end. The genes who adjust neural stem cells can express in glioma stem cells, which hold out glioma stem cells from neural stem cells. There is another presume that glioma stem cells come from differentiated cells. Through the gene break of these cells, they can obtain characteristics of stem cells, then form glioma stem cells.

神经干细胞具有很强的自我更新机制,获得较少突变即有可能恶性转化,而且干细胞存活时间较长,这意味着干细胞比成熟细胞发生细胞复制的错误几率更大,因外界环境的刺激而发生突变的机会更多,最终形成脑胶质瘤干细胞,同时调节神经干细胞增殖和自我更新的基因在脑胶质瘤的脑胶质瘤干细胞中也表达,这也是支持神经干细胞是脑胶质瘤干细胞来源的;也有推测认为它可能起源于已分化的细胞,由这些细胞突变发生去分化得来,并通过基因突变而获得了干细胞自我更新的特性,从而形成脑胶质瘤干细胞。

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