神经毒素

Objective To evaluate the analgesic effects of peritoneal injection of botulinum toxin type A in rat model of neuropathic pain.

目的 研究肉毒毒素A对神经病理性疼痛模型大鼠的镇痛作用，并探讨其可能机制。

The 35-year-old Chicagoan ordered 98 milligrams of Tetrodotoxin, a nerve toxin found in the Japanese puffer fish served as fugu, an expensive sashimi dish.

这位35岁的芝加哥人购买了98克的河豚毒素，这是一种在名叫河豚的日本魨鱼的身上发现的神经毒物。河豚是一种昂贵的用来做生鱼片的鱼类。

BACKGROUND: The mechanism of spasmodic dysphonia is still unclear and lacks of confirmed diagnostic standards. Limited reports on the treatment mainly focused on botulinum toxin infiltration; recurrent laryngeal nerve section, and voice training, amongst which voice training has been considered as one of the ideal complementary therapeutic means for SD because of less side effects and complications.

背景：目前痉挛性发声障碍病因不明，缺乏统一明确的诊断标准，故治疗较为困难，关于该病的治疗有限的报道主要是喉部肉毒杆菌毒素注射，喉返神经切断，发声语言训练等，其中后一种方法无副作用及并发症，是较为理想的治疗及辅助治疗手段之一。

As a type of bioactive compounds, paralytic shellfish poisons were mainly produced by dinoflagellate. PSP toxins have potential application in researches of harmful algal bloom toxicity, neurology and molecular biology, and development of new drug.

麻痹性贝毒（Paralytic Shellfish Poisons，PSP）毒素主要是由海洋甲藻产生的一类活性物质，在赤潮毒素监测、神经与分子生物学基础研究以及新型药物开发方面都有潜在的应用价值。

The answer lies in how Botox can be injected directly to the source of the problem -- usually an overactive muscle, gland or nerve connection -- with few lingering side effects, making it easy for scientists to experiment with it on different problems.

答案在于肉毒素可以直接注射到过于活跃的肌肉，腺体和神经连接处，这正是某些疾病产生的根源。使用肉毒素后持续的副反应较少，这就让科学家可以放心试验，运用肉毒素治疗各种疾病。

The effect of Coriaria lactone on amino acid nerve transmission substance: Coriaria lactone is a kind of nerve toxicant can made amino acid nerve transmission substance content of insect change and the content of GABA increase obviously, the content of Glu change little or decrease slightly.

马桑毒素对昆虫氨基酸神经递质的影响：马桑毒素是一种神经毒剂，作用于昆虫引起体内的氨基酸神经递质含量发生变化，其中GABA含量明显升高，GLU含量变化不大稍有下降，并且马桑毒素侵入虫体后，试虫具有兴奋-吐出中肠液-瘫软-昏迷-死亡的症状，表明马桑毒素是试虫的神经传导中GABA的特殊拮抗剂。

Methods Botulinum toxin type A was injected into neck muscles of 29 patients with idiopathic torticollis spasmodicus.

选取29例原发性痉挛性斜颈患者，应用A型肉毒毒素进行颈部肌肉注射治疗，检测和比较注射前、注射后1周和12～16周尺神经及胫神经F波的潜伏期及出现率。

They can also cause a neurological disorder known as tick paralysis.

有些硬蜱在叮刺吸血过程中唾液分泌的神经毒素可导致宿主运动性纤维的传导障碍，引起上行性肌肉麻痹现象，继而可导致呼吸衰竭而死亡，称为蜱瘫痪。

GM1 gangliosidoses, the specific component in lipid raft, was used as the hallmark of lipid raft. The distribution and expression of GM1 were probed by horse radish peroxidase coupled to cholera β-subunit, and revealed by chemiluminiscent HRP substrates.

再以脂筏的特有化学成分神经节苷脂GM1作为脂筏的标志分子，利用霍乱毒素β亚基能与GM1特异性结合的特性，以辣根过氧化物酶标记的霍乱毒素β亚基用点印迹法化学发光检测神经节背脂的分布，从而对脂能进行定性鉴定。

The results showed that the muscle weight of botulinum toxin injection side decreased. The craniofacial morphology of the botulinum toxin injection side were smaller in distances of zygomatic arch to mandibular lower border and ramus height than that of the normal saline injection side.

结果发现实验组大白鼠施打肉毒杆菌神经毒素侧其咬肌重量较施打生理食盐水侧及对照组小，其颅颜骨型态在颧骨弓至下颚骨缘距离，冠状突切迹最前端至下颚骨角状突最下点距离，均小於生理食盐水侧距离，有统计上之差异。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。