神经外的

Although the panel logit models verify the effects of the explanatory variables consistently with the theory, the prediction accuracy is not as good as that of neuro fuzzy. In addition to the better out-sample prediction accuracy, neuro fuzzy also provides a more detailed and complicated relationship among the variables through the rule base mid 3-dimension graphics, which could be used for further theory development or modification Overall, the banking crises ca be predictable; however, each country needs different forecasting model. The mapping between the forecasting model mid data set characteristics ca be further developed for the future research.

实证结果显示，虽然Panel Logit之固定效果与随机效果模型皆验证了过去理论上各变数对银行危机之影响方向，但整体而言，其预测准确度并不比类神经模糊好；而类神经模糊除了提供更准确的样本外预测之外，其所建构的规则库与3D图提供较以往更为细腻的变数关系，此关系可作为未来理论发展之基础；整体而言银行危机可以被有效的预测，然而单一国家的预测结果显示不同的国家适用不同的预测工具，没有一项工具能够适用於所有的国家；而资料集属性与预测工具之对应关系可作为未来之研究方向。

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析，并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、吲哚青绿血管造影(indocyanine green angiography，ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例，73.5%)，双眼同时患病118例(80.8%)；后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%)；前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例，98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%)；后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障；毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现；炎症活动期FFA典型表现为斑驳状高荧光，ICGA发现脉络膜血管扩张、通透性增高等改变；VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎，随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

Recently, it is proved that SP is also involved in pain modulation, acupuncture analgesia and immunoin- hibition. However, the role of CGRP in them is unclear Therefore, the dy- namic changes of CGRP-, SP-like immunoreactivity and expression ofα- CGRP,β-CGRP mRNAs in dorsal root ganglion and spinal cord in the arthritic rats were observed by using immunohistochemistry and in situ hybridization techniques combined with behavioral tests, respectively. Subsequently, the effects of this peoptide on the develoment of polyarthritis were investigated by intrthecal injections of CGRP and its antagonist in the rats. In addtion, GAL is a novel neuropeptide which coexists with CGRP and SP, but it may play a different role in the primary sensory system. Thus, we also observed the changes of GAL and GAL mRNA in DRG neurons and the spinal cord. The results were as follows

为此本文拟在大鼠佐剂性关节炎模型上，结合行为学测定、用免疫组织化学、原位核酸分子杂交技术观察脊髓背角及DRG中CGRP、SP、α-CGRP mRNA、β-CGRPmRNA的动态变化及电针的影响，此外，用鞘内和外周注射CGRP的工具药探讨了CGRP在佐剂性关节炎发生发展中的可能作用；甘丙肽（Galanin，GAL）也是新近发现的一个神经肽，并与CGRP和SP共存于DRG及初级传入末梢中，在神经损伤模型中脊髓CGRP、SP减少，GAL则明显增加，显示GAL与CGRP和SP的作用可能不同，因此在佐剂性关节炎模型上也同时观察了GAL和GAL mRNA的变化，实验结果如下

Results: Lateral extradural approach could be used to expose the second and third branches of trigeminal nerve,trigeminal ganglion,posterior vertical segment of the intrapetrosal ICA,abducent nerve and horizontal segment of the intrapetrosal ICA;lateral intradural approach could be used to expose the lateral,anteroinferior and posterosuperior venous spaces,almost all the cranial nerves within the cavernous sinus and horizontal segments of the intracavernous ICA;superior approach could be used to expose the medial,lateral and posterosuperior venous spaces,medial side of the anterior genu,anterior vertical and clinoidal segments of the intracavernous ICA and the lateral side of the hypophysis.

结果：外侧硬膜外入路可用于显露三叉神经第2、3支，三叉神经节，海绵窦内颈内动脉后垂直段，外展神经及岩骨颈内动脉水平段；侧方硬膜下入路可用于显露海绵窦外侧及前下，后上静脉间隙，以及所有走行在海绵窦内的颅神经和海绵窦内颈内动脉水平段；上方入路可用于显露海绵窦内侧、外侧及后上间隙，海绵窦内ICA水平段、前膝、前垂直段及床突段的内侧面，以及垂体的外侧面。

Methods: 50 normal Wistar male rats were randomly divided into five geoups: the sham operated group, injury model group, shenjindan capsule treat group, high dose and low dose group (duzhongyaotong pill treat, D and E)(n=10each). Autogenous nucleus pulposus was removed from the coccygeal vertebral and placed into the back of left L5~6 nerve root, The modle of the non-compressive nucleus pulposus protrusion was created by transplanting autogenous nucleus pulposus in the back of left L5~6 nerve roots. At tow weeks, the SP in dorsal root ganglion was determined by immunohistochemistry.

取健康Wistar大鼠50只，随机分为假手术组、模型组、对照组、高剂量组（D组、腰腿理痛散高剂量组）、低剂量组（E组、腰腿理痛散低剂量组），每组10只，将大鼠自身的尾椎髓核取出移植于左侧硬膜外腔L5、L6神经根背侧，造成非压迫性大鼠自体髓核移植硬膜外模型，通过免疫组化的方法测定大鼠2周时DRG中CGRP的变化。

It was suggested:(1) A strikingly strong sensitivity to eye gaze is observed from birth, and eye gaze perception is key to the development of language capabilities and social cognition;(2) The neural basis of gaze perception is the superior temporal sulcus, which is heavily connected with the amygdala implicated in processing emotion, and the STS is an important part of a wider network for social cognition neural systems;(3) Processing on early stage of eyes gaze cueing reveals specific event-related potential component;(4)The eyes gaze cueing effect has been labeled reflexive and likened to orienting in response to peripheral cues, however, it lasts longer;(5) The gaze cueing effect is influenced by many different facets, from lower level configural aspects such as face orientation to higher level cognitive factors. Furthermore, the gaze cueing effect reveals significant sex difference in normal adult population.

结果发现：婴儿从一出生就对眼睛注视线索表现出强烈的敏感性，眼睛注视知觉对语言和社会等能力的发展有很大影响；(2)颞上沟是加工眼睛注视线索的特异神经结构，它与实时监控情绪和情感的杏仁核存在神经联结，成为社会认知神经系统的重要组成部分；(3)对眼睛注视线索的早期加工显示出特异的脑电活动模式；(4)眼睛注视线索效应与外周线索的反射式效应相类似，但持续时间较长；(5)眼睛注视线索效应不仅受面部结构信息的影响，也受自上而下加工等高水平认知因素的调节，并显示出明显的个体差异。

2B8a was weakly reactive to neutrophils (23.72%) and negative for T cells, NK, DC, RBC and Plt. The antibody reacted to all 3 marrow CD34+ cells with an average positive rate of 39.33% while it was negative for G-CSF-mobilized CD34+ peripheral blood stem/progenitor cells (PBSC, 1.25%). Cell line analysis showed that the antibody notably reacted to three out of 4 cell lines (Raji, SMS-SB, Nalm-6 and Nall-1) with the positive rates of 98.78%, 98.61%, 94.93% respectively and weakly to one of them with 5.68% in B lineage cell lines and monoblastic cell line (U937, 67.78%) while it was only weakly positive or negative for other myeloid leukemia cell lines including Meg01 (33.40%), HL-60 (29.70%),K562 (28.19%), KG1a (16.23 %) and HEL92.1.7 (8.02%). Among 4 T lineage leukemia,5 neuroblastoma and 1 colon cancer cell lines tested, only Molt-3 was found weakly positive (31.40%) for 2B8a, while the remaining 3 T cell lines (Molt4, JM and CCRF-CEM), 5 neuroblastoma cell lines (LA-N1, KCNR, BE, SK-N-SH, SK-N-AS) and the colon cancer cell line (HR8348) tested were negative.

结果表明： 2B8a抗原在外周血B细胞上表达（3/3例，平均阳性细胞数为26.29 ％），而在T淋巴细胞和NK细胞上不表达（0/3例）；在粒细胞和单核细胞上阳性表达均为2/3例，平均阳性细胞数分别是23.72 ％和59.84 ％；在DC细胞、红细胞和血小板上均不表达（0/3例）。2B8a抗原在骨髓CD34＋细胞上的阳性表达是3/3例，平均阳性细胞数39.33 ％，而在G-CSF动员的外周血CD34+细胞上的阳性表达仅1/3例，平均阳性细胞数为1.25 ％。2B8a抗原在B系细胞系Raji、SMS-SB、Nalm-6和Nall-1上的平均阳性细胞数分别为98.78 ％、98.61 ％、94.93 ％和5.68 ％；在T系细胞系Molt-3上的平均阳性细胞数为31.40 ％，而在Molt-4、JM和CCRF-CEM 细胞上不表达；在髓系细胞系U937、Meg-01、HL-60、K562、KG1a和HEL92.1.7上的平均阳性细胞数分别为67.78 ％、33.40 ％、29.70 ％、28.19 ％、16.23 ％和8.02 ％；在神经母细胞瘤细胞系SK-N-SH、KCNR、BE、LAN-1和SK-N-AS细胞以及结肠癌细胞系HR8348细胞上均不表达，而在羊膜细胞系FL细胞上呈一定的阳性表达，平均阳性细胞数为45.03％。

The aim of the study is to improve the outcomes of shoulder abduction by accessory nerve transfer from the following two aspects:① Select the best choice of recipient nerve;②Design a dorsal-approach spinal accessory nerve transfer, more effevtively use the pinal accessory nerve.

本课题研究旨在从以下两个方面：①选择副神经移位恢复肩关节外展功能的最佳受区神经，②设计新的后入路副神经移位术式；提高副神经的利用效率，改善术后患者肩关节外展功能的恢复。

The transmission is conducted in the form of action potentials along the axon of DRG neuron to the presynaptic membrane in spinal dorsal horn. Action potential depolarizes the presynaptic membrane and activates the voltage-dependent Ca〓 channel. The influx of Ca〓 then triggers the release of neurotransmitter.

外界感觉信息以动作电位的形式沿DRG细胞轴突由外周传向DRG细胞在脊髓背角的突触前膜，导致细胞膜去极化，引起电压依赖性〓通道的开放，〓内流介导突触前膜神经递质的释放，从而完成感觉信息由外周向脊髓的传递。

Result and Conclusion:A neurological event was not the cause of any patient's death. 17 patients(6.2%) had clinically significant neurological disturbance postoperatively,of these 82.4% were central and 17.6% peripheral nerve pareses.

结果：心脏直视手术的神经系统并发症的发生率为6.2％，其中14／17为中枢神经系统并发症，3／17为外周神经轻瘫，除迟发性偏瘫预后较差外，其余的神经系统并发症预后较好。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。