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1 Day after injury ruptured capillary could be seen in ganglion cell layer, 4 weeks after injury cells in each layer arranged sparsely and disorderedly, in some RGCs chromatin became dense, 8 weeks after injury the cells in each layer became fewer and large amount of RGCs without nucleus could be seen.

3光镜下伤后1 d视网膜神经节细胞层出血,伤后4周视网膜各层细胞稀疏、排列欠整齐,GCL散在核染色质浓集、边聚的节细胞,伤后8周视网膜各层细胞明显减少,GCL内大量空化节细胞。

At four,eight or sixteen week after operation,the angiogenesis of NGF was evaluated with Hematoxylin and Eosin staining and electron microscope.

术后4、8、16周观察再生神经的大体形态,并用HE染色和透射电镜观察再生神经的束间及束内血管分布。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, which indicates PX and melatonin supplementation have no significant effect on CRH levels.

结果: ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低,提示松果体摘除后下丘脑CRH 神经元的表达增强;②松果体摘除大鼠补充褪黑素后,下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复,不过不论是低剂量组还是高剂量组,也不论是术后4 周还是术后8周,均不能恢复至正常;③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低,提示下丘脑CRH 神经元释放CRH 增加;④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性,表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, whichindicates PX and melatonin supplementation have no significant effect on CRH levels.

结果: ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低,提示松果体摘除后下丘脑CRH 神经元的表达增强;②松果体摘除大鼠补充褪黑素后,下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复,不过不论是低剂量组还是高剂量组,也不论是术后4 周还是术后8周,均不能恢复至正常;③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低,提示下丘脑CRH 神经元释放CRH 增加;④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性,表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

Conduits absorption and surrounding tissue cicatrization were observed at 1、2、4 weeks after neurotomy. And the nerve regeneration and functional recovery were evaluated by electrophysiology, histological changes, morphometric analysis, and weighing of gastrocnemius muscles at 6, 8 weeks afterneurotomy.

分别于术后1、2、4周观察桥接鞘管周围的瘢痕形成及吸收情况,并于术后6、8周行神经电生理、组织学观察、图象分析、腓肠肌湿重检测,比较各组大鼠坐骨神经的再生与功能恢复情况。

At G. 32W stable expression of nov mRNA was distributed in pontine abducens nucleus, red nucleus and substantia nigra of midbrain, ventral posterolateral thalamic nucleus and mediodorsal thalamic nucleus.

第32周脑桥展神经核、中脑红核和黑质、丘脑腹外侧核和背内侧核以及第38周大脑纹状体、顶叶皮质显示nov mRNA稳定的表达。

He Fengsheng using a rabbit, awee -k to 50 kg allyl chloride, three times a week. then to 100 kg, three times a week for five to six weeks after similar toxic nerve disorder symptoms.

何凤生[5]等用家兔,第1周给50 mg/kg 氯丙烯,每周3次,然后给100 mg/kg ,每周3次,5到6周后出现类似的中毒性神经运动障碍症状。

NMES devices were used and the surface electrodes were applied on the ankle dorsiflexor in ...

研究组患儿在此基础上增加NMES结合肌力训练,NMES采用电刺激仪,4个表面电极放置于患侧足背伸肌群肌腹处给予电刺激,20min/次;肌力训练根据脑瘫患儿的运动功能状况,结合运动学理论、运动学习理论和神经发育学理论等进行针对性训练;1次/d,5次/周,连续6周。

MSCs were transplanted to infracted area of brain stereotactically,for comparsion with sham operation transplantation group and CI control group...

结果:移植入脑的MSCs在正常脑组织与梗死区能存活至少4周以上,并发生迁移,至第3周移植治疗组迁移范围为(3.626±1.831)mm2,明显比假手术移植组(1.534±0.475)mm2大,差异有显著性意义(F=5.7863,P.05);接受MSCs移植后大鼠改良神经功能缺损量表得分低于另两组。

Methods 65 patients with peripheral neuritis caused by CHOP regimen were divided into 3 groups.A group 15 patients as control group accepted chemotherapy only.

方法采用CHOP化疗方案出现周围神经系统疾病的65例NHL患者随机分为A、B、C三组。A组15例,未治疗;B组25例,弥可保针剂0.5 mg,肌肉注射,1次/d,2周;C组25例,神经妥乐平针剂7.2 Nu,静脉滴注,1次/d,2周。

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