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There has been positive fiber in the neurofibra of spiral ganglion and in the cochlea nerve of modiolus by ANP immunological reaction.

大多数螺旋神经节细胞为ANP免疫反应阳性细胞,棕色ANP免疫反应产物散布在胞浆内,少数神经节的胞核也被阳性染色。

The increase of ganglion volume mainly lied in growth of neurons and increasing of nerve fibers and neuroglia cells, but not lied in marked increase of neurons in number.

山羊胎儿脊神经节于胚胎第6周就已形成,但此时节内神经元形态不清晰,至第8周,节内神经元形态逐渐清晰,节内神经纤维数量少;随着胚胎发育,节内神经元数量并不显著增加,而是节细胞之间神经纤维及胶质细胞的增多和神经元个体的增长,从而使神经节的体积逐渐增大。

Retrograde tracing revealed that regenerated axons originated from brain stem nuclei, including red nucleus, locus coeruleus, raphe nucleus, vestibular nucleus, and reticular formation.

神经逆向追踪结果证实移植细胞后可帮助上脊髓神经核包括红核、蓝斑核、缝核、前庭核及网状结构内的神经元再生。

To sum up, main results of this study were listed as follows:(1) After analyzing the main factors affecting generalization function of neural network, and aiming at poor representativity of hydrologic time series samples, standardization method of transforming extreme was presented to deal with input sample of time series, which could make the input samples lie in the interpolation range of training samples even if they lie in the extension of training samples, so it improved generalization function of neural network and accelerates network convergence speed.

概括起来,本文取得的主要研究成果如下:(1)对影响神经网络泛化能力的主要原因进行了阐述,针对水文时间序列样本的代表性不好这一问题,提出了采用变最值的规范化方法处理时间序列输入样本,使神经网络的输入样本即使为训练样本的外延,规范化后也处于训练样本的内插范围,从而改善神经网络的泛化能力,并加快网络收敛速度。

Previous studies have revealed that aganglionic or morphological and numerical abnormalities of the intestinal intramural ganglia may contribute to the pathogenesis of the intestine motility obstacle of them.

目前认为HD和HAD肠动力障碍的发病机制主要是病变肠段粘膜下神经丛和肌间神经丛的神经节细胞的缺失和减少,病变肠壁内的副交感、交感及第三类神经系统均有改变。

The correlation between intraneural injectionand neurological dysfunction remains unclear.

神经内注射和神经能不全的关系仍不明确。

Methods Properties of C unit in superficial branch of radial nerve were observed on diabetic neuropathic patients, using intraneural microrecording methods.

用神经内微记录方法,观察糖尿病性神经病患者桡神经浅支中C单位的反应特性。

Methods Seventy-eight adult female PVGrats were divided into experimental group (n=60) and control group (n=18), intraneural injection technique was used to supply three kinds of NO donors with different half-life(DETA NONOate, DPTANONOate and Spermine NONOate) or saline into the rat sciatic nerve subperineurally under light microscope. At the 1th,2th,3th,7th,and 14th day of duration after sciatic nerve injection, a segment of injected sciatic nerve was taken out and embedded it in TAAB resin after tissue processing. Then it was cut into thin layers (1μm) and the histological changes were observed under high power microscope, meantime the number of degenerated axons were counted.

选择78只雌性PVG大鼠,分为实验组和对照组,以在体神经内微注射实验方法,将三种半衰期不同的NO供体(DETA NONOate,DPTA NONOate和Spermine NONOate)及生理盐水分别注入大鼠左侧坐骨神经的神经束膜下,于注射后的不同时间(1天、2天、3天、7天和14天)取出注射部位的坐骨神经,经组织学处理后做成树脂包埋块,以超薄切片机切片,然后在高倍显微镜下观察并计数神经横断面的变性轴突数目。

Antinociception and VGSC-modulation of BmK IT2 and BmK AS—1. The results from nociceptive flexion reflex and plantar radiation heat showed: BmK IT2 (a depressant insect-selective neurotoixn) and BmK AS-1 (a new-type β-1ike neurotoxin) have significant antinociceptive effects on rat peripheral nerve system. The antinociceptive effects of BmK IT2 on the carrageenan-inflamed rats were significantly stronger than those on the normal rats. Whole-cell patch-clamping showed: Both TTX-S and TTX-R Na〓 currents induced from rat DRG neurons were significantly inhibited by BmK IT2 and BmK AS—1, and BmK IT2 was more sensitive to TTX-R than TTX-S component. All the results suggested: the peripheral antinociception of BmK IT2 and BmK AS—1 might be attributed to the inhibitory effects of them on the TTX-S and TTX-R Na〓 channel located on the peripheral ends of rat DRG neurons with small diameter.

中文题名特异性钠通道调制剂-长链蝎神经毒素的药理功能研究副题名外文题名 The study of pharmacological function of the specific modulators on voltage-gate Na+ channel-long chain scorpion neurotoxin 论文作者谭智勇导师吉永华研究员学科专业生理学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数93页关键词神经毒素毒理学电压门控钠通道东亚钳蝎钠通道调制剂馆藏号BSLW /2003 /R338 /22 本论文工作利用细胞和行为药理技术系统地研究了东亚钳蝎长链神经毒素的抗伤害性效应、对电压门控钠通道的电生理调制作用、改变胞内离子浓度的效应,并分析了相关的药理功能机制。

Limited by current microelectronics technology, the types and scales of neural network model supported by neurochips are being reduced. Neurochips are only suitable for some special application fields.

受当前微电子技术水平的限制,神经芯片所能支持的神经网络计算的规模和类型都很有限,比较适合于一些专用领域内的小规模神经网络计算。

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