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"In some damaged brains, like after a stroke, there is no neurogenesis," he says.

"在一些受损的大脑内,例如中风后,没有了神经形成,"他说,我们感兴趣的是这些神经细胞从哪里来,以及我们是否可以刺激神经形成。

Methods A concept of compartmental localization of heel, including the low area, posterior area, upper area, medial area and lateral area was considered on the base of anatomy, and the difference of soft tissue deepth, compression resistance, confiction resistance, according to which the feeling function was reconstructed by the flaps based on vessel and nerve, or by the flaps based on vessel with nerve anastomasis.

对足跟进行解剖学观察,分别测量各部位软组织厚度,根据各部位承受重力及摩擦程度不同,将跟分为跟底、跟后、跟上、跟内、跟外5个区域。修复时根据各个创面所在区域及软组织厚度不同特点,选择不同的带血管、神经蒂皮瓣或吻合神经的带血管蒂皮瓣转移。

In NBS, lesions therefore appear secondary to the small vessel vasculitis, and the anatomy of those intraaxial venous structures explains the dominant involvement of the upper brain stem and diencephalic structures.

神经白塞病患者的病灶系小血管炎所致,因此,脑内静脉结构的解剖学特点可以解释神经白塞病常易累及脑干上部和间脑结构。

Five patterns of perineural invasion were observed and 3 nerve plexuses in the hepatoduodenal ligament and Glisson sheath were found.

肿瘤浸润神经有5种方式,肝十二指肠韧带与一、二级肝管所在的Glisson鞘内分布的神经丛主要有3丛。

Results MRI appearances of acoustic neuromas were:(1)The turmor's growth round the internal auditory canal,the Ⅶ,Ⅷ nerves affected side were thickened than that of opposite side.There was no marked demarcation between the main bodies of the tumors and the affected nerves.The connection between tumors and affected nerves could be showed at contrast enhanced imaging.(2)The tumors were of hypo or isohypo intensity on T1 weighted images and hyper or iso hyper intensity on T2 weighted images.(3)After Gd DTPA administration the tumors were homogeneously or inhomogeneously or circularly enhanced.(4)The margins of the tumors were smooth and well delineated.(5)The affected internal auditory canal usually became shorter in depth and larger in posterior anterior diameter.(6)MRI appearances of micro acoustic neuromas were that the affected Ⅶ,Ⅷ nerves were normal in size or nodularly thickened and the tumor reveaed nodular or point enhancement at contrast enhanced MRI.

结果 听神经瘤的MRI表现主要为:(1)肿瘤以内听道为中心生长,第Ⅶ、Ⅷ神经束较对侧增粗,与肿瘤主体多无明确分界,增强后可见两者相连,颇为特征;(2)肿瘤在T1加权图像上呈低信号、略低信号或低等混合信号,T2加权呈高信号或高等混合信号;(3)注射Gd DTPA后肿瘤呈均匀、不均匀或环状强化;(4)肿瘤边界清晰,边缘光整;(5)绝大多数肿瘤患侧内听道前后径扩大,深径缩短;(6)微小听神经瘤的MRI表现为第Ⅶ、Ⅷ神经束正常或局部结状增粗,造影后呈结节状或点状增强。

In particular,peripheral contrast enhancement with separations of an intradural extramedullaty tumor on MRI will suggest the diagnosis of schwannoma.

椎管内髓外硬膜下神经鞘瘤的MRI特征,有助于椎管肿瘤的鉴别诊断,尤其是伴有瘤内分隔性周围强化,应提示神经鞘瘤。

Besides neurokinins, recently we found that the dominant opioid receptor, delta subtype, was existed in renal pelvis and intrapelvic activation of DOR resulted dose-dependent increases in ANRA, suggested that DOR plays a role in regulating renal sensory response.

除了神经激肽受体之外,本实验室最近也发现类鸦片受体在肾盂表现并且其中以delta亚型的类鸦片受体(delta-opioid receptor, DOR)为主,活化肾盂内DOR可够剂量依存性地增加传入性肾神经的活性,所以DOR可调控肾脏感觉功能。

Methods:①Conducted time,amplitude and NCV of motor evoked potentials at ulnar nerves 5 cm above and below the elbow(total 10 cm)were detected in 42 patients with CuTS in the early stage,and the results were compared with those of 30 healthy persons as the control,to locate the actual wedge position;②To measure the orthodromic nerves sensory conduc- tion velocityof ulnar ne...

①对42例早期CuTS患者的肘部上、下各5cm(共10cm)运动诱发动作电位传导时间、波幅进行测定,计算出运动神经传导速度,并与30例正常对照者的检测结果比较,确认肘管内嵌压部位;②对尺神经进行顺向感觉传导速度测定;③对前臂肌与手内肌进行针电极肌电图检测,帮助判定尺神经损害。

Result: Schwann-like cells disperse in the hole of nerve graft at oneweek under Scanning Electronic Microscope, the processes of thesatellite-like cells adhere to the wall of graft.There was no statisticaldifference of activity of cells in both group(P>0.05) using MTT. At 12weeks,the result of appearance, histology and TEM were similar, therewere no statistical difference in SFI%, NEP and quantitative analysis ofrecovery rate of myelinated fiber populations, diameter of myelinatedfiber and thickness of myelin sheat.

结果:1w后扫描电镜下可见接种的类Schwann细胞分散在材料表面的孔隙内,细胞形态为星状,细胞突起与支架管壁粘附;MTT法测定细胞活性示神经支架组在各时间点与对照组无显著性差异P>0.05;12w时两组动物坐骨神经外观、组织学光镜观察、透射电镜观察结果相似、两组坐骨神经功能指数恢复率、神经电生理、再生有髓神经纤维计数恢复率、神经纤维直径恢复率、髓鞘厚度恢复率等指标相比无显著性差异(P>0.05)。

The opioid receptor agonist at the supraspinal site failed to alter the pelvic nerve activity suggest that supraspinal endogenous opioid system does not act directly on the sacral preganglionic neurons, but indirectly through descending fibers on the interneuron at the level of afferent inputs in the sacral spinal cord.

由於注射此药物到侧脑室中,并不会对骨盆神经之活性造成影响,因此推论上脊髓部位的内吗啡系统,并不会直接影响副交感神经节前神经元之活性,其作用可能在中问神经元或膀胱的输入神经。

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