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The role of cystatin C to the neurite outgrowth was subsequently tested by primary neuronal culture.

随后我们用神经元的原代培养实验检测了Cystatin C对神经元突起生长的作用。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, which indicates PX and melatonin supplementation have no significant effect on CRH levels.

结果: ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低,提示松果体摘除后下丘脑CRH 神经元的表达增强;②松果体摘除大鼠补充褪黑素后,下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复,不过不论是低剂量组还是高剂量组,也不论是术后4 周还是术后8周,均不能恢复至正常;③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低,提示下丘脑CRH 神经元释放CRH 增加;④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性,表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, whichindicates PX and melatonin supplementation have no significant effect on CRH levels.

结果: ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低,提示松果体摘除后下丘脑CRH 神经元的表达增强;②松果体摘除大鼠补充褪黑素后,下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复,不过不论是低剂量组还是高剂量组,也不论是术后4 周还是术后8周,均不能恢复至正常;③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低,提示下丘脑CRH 神经元释放CRH 增加;④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性,表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

The output of one neuron can be given as input to multiple neurons.

一个神经元的输出,可作为多个神经元的输入。

The results showed that the avian nLM cells were sensitive to edges moving across their ERFs, depending on the contrast, length, and orientation, but not on the shape and area size of the stimuli.

主要证据有:(1)运动边缘可诱导出强烈的视觉发放;(2)神经元视觉发放与刺激物形状和大小无关;(3)刺激物边缘模糊后神经元的视觉反应明显下降。

Methods The influence of DA on the electric activity of the pain-excited neuron in the caudate nucleus of normal rats or morphinistic rats was recorded after the sciatic nerve was noxiously stimulated.

在给予坐骨神经伤害性刺激后,记录中枢痛兴奋神经元的电活动,观察多巴胺对正常大鼠和吗啡成瘾大鼠中枢痛兴奋神经元电活动的影响。

NYA can promote the differention from NSC to neuron, and survival.

脑溢安可促进神经干细胞向神经元方向分化,提高神经干细胞分化为神经元的比率,并具有促进神经细胞存活的作用。

under the effect of aconitine, spontaneous activity in injured drg neurons can change firing patterns.

在阻断钠通道失活门之后,受损drg神经元的自发放电可以发生模式转化,并且乌头碱对drg神经元的作用具有活动依赖性。

Autoradiographic studies have demonstrated that adenosine A1 and A2 receptors are expressed in the spinal dorsal horn, both on the post-synaptic SG neurons and the central terminals of the primary afferent neurons.

放射自显影的结果表明A_1和A_2受体都分布在脊髓背角,包括突触后SG神经元和初级传入神经元的中枢突,而A_1受体集中分布于胶状质。

Objective: To study the enzymic changes and protective effect of ciliary neurotrophic factor on neurons in spinal cord injury.

目的:研究脊髓损伤后脊髓神经元内酶学的变化,并探索睫状神经营养因子对神经元的保护作用。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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