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Immunoprecipitation and cresyl fast violet staining were employed to detect the expression of relevant message proteins, activation and the death of the hippocampal neurons.results it was found that hpk1 was expressed in rat hippocampus neurons.conclusions administration of hpk1 antisense oligodeoxynucleotides can significantly protect hippocampus neurons from apoptosis without dose-dependence.

使用免疫沉淀和焦油紫染色法等技术检测相关信号蛋白的表达、活化水平及神经元细胞的死亡。结果在大鼠海马神经元中有hpk1的表达,脑室注射as-odns大鼠海马ca1区存活锥体细胞明显增多。结论 hpk1反义寡核苷酸对缺血/再灌注引起的海马神经元凋亡具有保护作用。

Results from whole-cell patch clamp showed: 1 BmK Ⅰ(α-like neurotoxin) was found to prolong the duration of action potential and promote the amplitude of action potential. The effects could be attributed to the selective action of BmK Ⅰ on the TTX-S Na〓 channel: slowing the inactivation process of Na〓 channel, increasing the amplitude of peak Na〓 currents; 2 BmK abT, a new-type neurotoxin with higher sequence homology to β-type scorpion neurotoxin, was found to slow the inactivation process of Na〓 channel and prolong the duration of action potential in DRG neurons.

全细胞膜片钳研究发现:1)类α型哺乳动物毒素BmK Ⅰ可延长部分DRG神经元全细胞动作电位的时程,增加动作电位的幅度,这些效应可归咎于BmK Ⅰ选择性地作用于DRG神经元TTX—S钠通道,延缓TTX—S钠电流的失活化相,峰钠电流幅度增加;2)BmK abT,一个与β型毒素同源性较高的新型蝎毒素可抑制DRG神经元全细胞钠电流失活化过程,使动作电位时程增加。

With billions of neurons, each with thousands of connections, one's noggin is a complex, and yes congested, mental freeway.

一个人的脑袋是一个复杂且拥挤的精神"高速公路",拥有数以十亿计的神经元,并且每个神经元都和数千的神经元相互联系。

The computational power of the quantum neuron is explored. Numerical and graphical results show that this single quantum neuron can perform XOR function unrealizable with a classical neuron and has the same computational power as the two-layer NN, it can be used to realize nonlinear mapping.

应用量子计算方法分析了该量子神经元模型的量子逻辑运算功能,分析和实验证明单个量子神经元能实现经典神经元无法实现的XOR函数,并具有与两层前向神经网络相当的非线性映射能力。

Based on Rough Set Theory, a neuralnetwork model of enterprise tacit knowledge communication isestablished and studied. Followingly this part discusses thedecision-making mechanism of enterprise tacit knowledgecommunication. R analyzes the multiple attribute decision-makings inenterprise tacit knowledge learning and a multiple attributedecision-making model is provided.

运用粗糙集理论对条件属性进行相对约简,通过去掉冗余条件属性,得到决策表的最小条件属性集和核,以决策表的某个约简作为输入层神经元,根据经验公式确定隐含层神经元个数,并以核元素连接对应输出层神经元,通过去掉冗余训练样本,提高沟通的学习效率,构建了企业隐性知识沟通神经网络优化模型。

NAA is the most sensitive marker of early brain damage decreased NAA correlate with prolongation of seizure time and loss of neurons; the change of Lac reflected moderate to severe injury of neurons;Increase in Cho may represent gliosis;decreased GABA can be detected when neuronal damage becomes severe.

1H MRS检出的NAA是反映早期脑损害的最敏感指标,其含量因癫痫持续时间延长和神经元数量减少而降低;Lac可以反映中等程度以上的神经元损害; Cho值升高,可能反映胶质增生;GABA值降低在神经元损伤较严重时可检出。

Results Apoptotic cells were found among normal dentate hilus cells and CA1 cells. Chromatin condensation and clumping could be seen in the apoptotic nuclei. The shrinkage of the nucleus was shown by foldings and whorls of the nuclear membrane. At late stage of apoptosis, the nuclear membranes could be broken.

结果 电镜下,实验组大鼠海马齿状回门区和CA1区内可见散在的凋亡神经元,凋亡神经元主要表现为核周染色体的聚集和凝结成块,其核膜表现为皱缩和扭曲,在晚期凋亡的神经元有时可见核膜破裂。

At histopathologic analysis, neuronal tumors are usually classified as pure neuronal cell tumors (gangliocytoma, Lhermitte-Duclos disease , central neurocytoma) and mixed neuronal-glial tumors (ganglioglioma, desmoplastic infantile ganglioglioma, dysembryoplastic neuroepithelial tumor, ganglioneuroma).

根据组织病理学的分析,神经元肿瘤通常被分为:单纯的神经元细胞肿瘤(神经节细胞瘤,Lhermitte-Duclos 病〔发育不良性小脑神经节细胞〕瘤),中枢神经细胞瘤)和混合性的神经元-胶质肿瘤(神经节神经胶质瘤,成结缔组织性婴儿节细胞胶质瘤,胚胎发育不良性神经上皮瘤,神经节瘤)。

It was observed by Nissl and enzyme histochemistry staining that exogenous GDNF decreased lesion-induced motor neuron death in lateral nucleus of spinal anterior horn and the changes in activity of cholinesterase and acid phosphatase in spinal cord and sensory ganglions.

采用硅管套接大鼠切断的坐骨神经模型,局部给予胶质细胞源性神经营养因子,应用尼氏染色、酶组织化学染色方法,观察到外源性GDNF能减少脊髓修复侧前角运动神经元死亡的数目,降低脊髓前角运动神经元及脊神经节感觉神经元中胆碱酯酶及酸性磷酸酶变化的幅度。

Results: The immunostaining showed that intense FOS-Li and moderate NKR-Li neurons in the superficial laminae of medullae oblongata dorsal horn and their mainly part of the distribution were overlapped. Parts of the distribution of NKR-Li were obviously overlapped by the BSI-B4 labeled primary afferent C fibers and terminals.

结果:再次于形态学上证实了NKR样阳性结构及初级传入C纤维在大鼠延髓内的分布;发现大鼠延髓后角浅层密集分布NKR样阳性结构或BSI-B4标记的C纤维阳性纤维及终末,I、Ⅱ层内可见NKR样阳性神经元、深层偶见NKR样阳性神经元;但其中极少数是c-fos阳性神经元,未发现典型的NKR/FOS双标细胞。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。