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Based on the stability theory of dynamical system, numerical computation of bifurcation diagram and the largest Lyapunov exponent of the linearized systems, the synchronization dynamics of coupled fast spike neurons with excitory chemical synapse was studied.

基于动力系统的稳定性理论、数值计算分岔图和线性化系统的最大Lyapunov指数,研究了经兴奋性化学耦合的快峰神经元的同步动力学。

Recently, it has been reported that Cav-1 was located over the entire hippocampus neuronal surfaces; high level of Cav-1 expression was also focally enriched on growth cones.

最近发现,Cav-1蛋白在培养的海马神经元的终末和轴突生长锥上有丰富的表达,提示Cav-1可能参与突触可塑性的调节。

During the latent and chronic phases, the metabolic level in the hilus of adult and PN21 epileptic rats was normal although neuronal loss reached 60–75%.

在潜伏期和慢性期,成年大鼠门部和致癫的PN21大鼠的代谢水平是正常的,尽管神经元的丢失达成到60-75 %。

Result:D-galactose induced neuronal injury and reduced neurogenesis in hippocampal CA1,CA3 and DG subfields.TUNEL-positive neurons distributed in the juncture between granular cell layer and hilus,where neural progenitor cells exist.

结果:在模型鼠海马DG区的颗粒细胞和CA1、CA3区可观察到锥形神经元的死亡,TUNEL阳性细胞位于神经前体细胞所在的颗粒细胞层和门区的交界处。

Based on above results, we conclude that the synaptic depression of thalamic input to the cortex contributes to rapid adaptation in cortical neuron, and both the thalamocortical and intracortical synaptic transmission could then enhance the degree of adaptation.

基于以上结果,我们认为,持续刺激引起的丘脑—皮层突触的抑制对皮层神经元的快速适应有贡献,而丘脑—皮层突触以及皮层—皮层突触的放大机制都可以将这一特性进一步增强。

To clarify the effect of lidocaine oncholinergic synapse, we reconstructed a cultured soma–somachemical synapse model consisting of two identified visceraldorsal 4 (VD4) and left pedal e-1 (LPeD1) neurons from the snail, Lymnaea stagnalis , in vitro , and used it to determine how lidocaineaffects cholinergic synaptic transmission.

为了阐明利多卡因对胆碱能突触的影响,我们从椎实螺属 stagnalis 的蜗牛离体重建了含两种已被鉴定的内脏背4( VD4)和左足 e-1( LPeD1)神经元的培养体细胞-体细胞化学突触模型,来研究利多卡因如何影响胆碱能突触传递。

With the property of self-renewing, stem cells transplanted into the injured locations can release some neurotrophic factors which can promote the regeneration of neuron and the neuraxon can drill through the boundary between the implant and host tissue to reconstruct the continuity of neuraxon.

干细胞具有自我更新能力,植入受损部位后,其释放的营养因子能促进神经元的再生,且再生轴突能快速穿越移植物与宿主组织的边界,重建轴突的连续性。

To 26. 23, P <0. 01.CONCLUSION: Chlamys farreri is capable of increasing Bcl-2 protein and decreasing Bax protein in cerebral penumbra to brake the initiation of neuron apoptosis after ischemia-reperfusion and preserve neuronic function in penumbra.

扇贝多肽能够上调脑缺血半影区内抑制神经细胞凋亡的Bcl-2蛋白水平,同时降低半影区内诱导神经细胞凋亡的Bax蛋白的表达,从而在阻止脑缺血再灌注后细胞凋亡启动中起制动作用,保护脑缺血后半影区内神经元的功能。

Results Many neuronal cell bodies and fibers with dense mGluR7-like immunoreactivity were intensely distributed in the island of Calleja,hippocampus,dentate gyrus,medial habenular nucleus,olivary pretectal nucleus,zonal layer of the superior colliculus,superficial layers of the caudal spinal trigeminal nucleus,paratrigeminal nucleus,raphe magnus nucleus,raphe nucleus pallidus,locus coeruleus,superficial layers and lateral spinal nucleus of the spinal cord.

近年来,大量生理学和药理学实验表明,Glu还可通过与G蛋白偶联的一类受体来调节兴奋性突触的活动和神经元的兴奋性,此类受体被命名为代谢型谷氨酸受体(metabotropic glutamate receptors,mGluRs)。目前应用分子生物学技术已成功地克隆出mGluR的8种亚型(mGluR1-8)[2~7]。

Whole-cellpatch-clamp technology demonstrated that VDPG (1g/L) had notsignificant effects on the delayed-rectified K~+ current, TTX-sensitive Na~+ current and high-voltage-activated Ca~(2+) current of rat dorsalroot ganglion cells. The fast transiet K~+ current of cottonbollworm dorsal DUM cells, the fast transiet K~+ current, Na~+ current andhigh-voltage-activated Ca~(2+) current of Periplaneta Americana dorsalunpaired median cells were also not significantly affected byVDPG at the same concentration. However, VDPG had significant effecton the fast transiet K~+ current of Pieris rapae. The VES had not significanteffects on the high-voltage-activated and low-voltage-activated Ca~(2+)current of rat DRG cells.

膜片钳电生理实验显示1g/L毒囊粗毒对蜚蠊DUM神经元的快瞬时钾电流、钠电流、高电压激活的钙电流,对棉铃虫快瞬时钾电流和大鼠DRG细胞延迟整流钾电流、TTX-S型钠电流、高电压激活的钙电流均无明显作用,却对菜青虫快瞬时钾电流有明显作用;电刺激粗毒对大鼠DRG细胞低电压和高电压激活的钙通道无明显作用。

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