神经元的

ChAc is an Ach's biological synthesizing enzyme and special mark of every cholinergic neuron.

ChAc是乙酰胆碱的生物合成酶，也是胆碱能神经元的特异标志酶，存在于所有胆碱能神经元，ChAc免疫反应活性被用于鉴别中枢和外周的胆碱能神经元。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. The n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. Then 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. The n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数来评估神经元的情况。

GDNF may be related to the mechanism of neuronic injury and repairment. Protective effects of VPA may be involve in increasing expression of GDNF.

帕金森病小鼠神经元内GDNF含量增多，可能有利于受损神经元的修复；丙戊酸盐可能通过促进GDNF的表达而保护神经元。

The model of brain concussion of rat can be established successfully using iron pendulum hitting device; 2. The spatial learning and memory deficits of the rats are detected by MWM in early period post-BC(from 1 to 3 days after BC); 3. Pycnosis degeneration or necrosis neurons of the cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation are identified in BC rats; 4. There are significantly changes in the number and activity of cholinergic neurons in the basal forebrain and brainstem reticular formation after BC; 5. The change of cerebral neurons and cholinergic neurons correlate with cognitive deficits in BC rats .

1、单摆式闭合性机械打击装置能成功建立脑震荡大鼠模型；2、脑震荡大鼠在MWM实验中出现早期空间认知行为障碍；3、脑震荡大鼠大脑皮质、背侧海马、齿状回和脑干网状结构出现程度不等的部分神经元固缩变性和不完全性坏死；4、脑震荡大鼠基底前脑、脑干网状结构ChAT活性表达有明显变化；5、脑震荡大鼠认知障碍与相关脑区神经元、胆碱能神经元的变化有关联。

MSG could insult the functions and structures of specific brain areas of adult mice through blood-brain barrier. The ability of discrimination learning in Y-maze was affected markedly, especially in 4. 0g/kg MSG group, meanwhile, dark pyknotic and loss of neurons were shown in arcuate nucleus of hypothalamus, but not in hippocampus. Consistent changes occured in mitochondrial membrane protein bound 〓 by 〓-fluoresent probe, i.

MSG可以透过成年小鼠血脑屏障产生神经毒性作用。4.0g/kg MSG对小鼠空间分辨学习能力的损伤程度较2.5g/kg MSG更为明显，同时下丘脑弓状核神经元出现核固缩及神经元数目明显减少，相同处理未引起海马神经元的明显变化。

First, the SVZa NSCs continuously migrate from SVZa to olfactory bulb in mammal whole life, form the rostral migratory stream and become the resource of OB interneuron renewing.

与其他部位的神经干细胞相比，SVZa神经干细胞还具有以下特点：(1)自产生时起即具备发育为神经元的特征；(2)迁移过程中保持增殖状态和神经元特征而不进一步分化；(3)到达迁移终点后，才进一步分化为DA能和GABA能神经元。

The phrenic nerve discharges were recorded by biopolar silver electrode, and the discharges of respiratory neurons were recorded by extracellular glass microelectrode,so the types of neurons were determined by the phasic relationship between the discharges of respiratory neurons and phrenic nerve efferents.

用双极银丝电极记录膈神经传出放电，用玻璃微电极细胞外记录延髓呼吸相关神经元单位放电，根据神经元放电和膈神经放电的时相关系来确定神经元的性质。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。