神经元的

Objective To investigate the expression of muscarinic acetylcholine receptors and GABAB receptors in lamina Ⅱ neurons in spinal cord.

目的观察M胆碱能受体亚型M2和B型γ-氨基丁酸受体在脊髓Ⅱ板层神经元的表达情况。

Objective To investigate the involvement of upper motor neuron in amyotrophic lateral sclerosis patients using diffusion tensor imaging.

目的采用DTI技术，定量检测肌萎缩侧索硬化症患者脑内上运动神经元的受累情况。

Objective To evaluate the effect and functional mecheism of JinNaDuo to protect neuron of cereˉbra following acute ischemia.

目的 探讨金纳多对缺血后再灌流神经元的保护作用及作用机制。

Objective To eva luate the effect and functional mecheism of JinNaDuo to protect neuron of cereˉbra following acute ischemia.

目的 探讨金纳多对缺血后再灌流神经元的保护作用及作用机制。

It employs the complex-valued step function to build neural model, then constructs network structure and decides the number of neurons; it adopts complex-valued Hebbian rules and inner product way to calculate the net weight matrix; then it analyzes the convergence of the network by taking advantage of the definition of energy function. In the image pre-processing stage, 2-dimensional Fourier Transform and Euler's formula are used, respectively, to transfer a gray-scaled image into phase information needed by the complex-valued neural network when stores the traffic sign. In the image post-processing stage, phase inverse transformation is used to change the phase image to gray-scaled image.

采用复数阶跃函数构建了神经元模型，建立了复数Hopfield神经网络结构，并且确定了网络中神经元的个数；借助复数Hebbian学习规则和复数内积法给出了网络权值的确定方法；借用复数网络能量函数的定义，说明了复数识别网络的收敛性；在前期的图像数据处理部分，分别使用离散二维傅里叶变换和欧拉公式，给出了将灰度图像数据转化为复数网络所需要的相位信息的方法，实现了网络对路牌的记忆存储；在后期的图像还原部分利用相位逆变换的方法，实现了相位图到灰度图转化。

The former, intracranially complements patients some factors, most frequently with TH gene to compensate scanty of intrastriatal DA and improve the symptoms of the patients, while have little resistance to the progressive degeneration of dopaminergic neurons; The latter provide variety of neurotrophic factors, most specific being the glial cell-line derived neurotrophic factor , to protect the residual DA neurons in the nigrostriatal system from further pathogenic injuries, while have little benefit to those DA neurons with irreversible damage, and them cannot offset the already-existing symptoms.

前者是给宿主脑内补充某些因子，主要是DA合成过程中的限速酶TH基因，以补充纹状体内DA含量的不足，减轻患者的症状，但对DA能神经元的进行性退变没有治疗效果；后者则是提供各种神经营养因子其中最具特异性的为GDNF，以保护黑质一纹状体系统内剩余的DA能经元免受病因的继续损害但对已发生不可逆性损害的DA能神经元并无拯救作用，无法消除已出现的症状。

The dopamine release in vivo was monitored by fast cyclic voltammetry and the concentrations of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic acid were determined by high performance liquid chromatography electrochemical detection in the process study. In addition, the effects of some traditional Chinese herbs and related marine drug on behavioral changes were also evaluated in order to provide some suggestive clue for rational drug design of anti-Parkinon's disease .

许多因素都参与PD的DA能神经元的死亡，所以，本研究在制备PD动物模型的基础上，应用国内率先引进的快速周期伏安法检测设备在体动态监测DA的释放，同时应用另一种电化学检测技术—高效液相色谱电化学检测法离体检测DA及其代谢产物二羟苯乙酸和高香草酸的含量，结合行为学测定及其它方法，研究了雌激素和铁在PD发病中的作用，以及一些药物，如吲哚醌、牛磺酸、铁离子螯合剂、胆囊收缩素（CCK-8）、乌鸡白凤丸有效成份、大豆异黄酮及海洋酸性寡糖HSH971，对DA能神经元的影响，从DA能神经递质角度对PD的发病机理提供进一步的实验依据，并为PD的预防和治疗提供新的干预措施。

High brain iron involved in the etiology of PD, while iron chelator desferrioxamine mesylate could protect DA neurons.

6.6-OHDA可导致Str的DA释放量及含量均减少，此过程有铁的参与，由于铁可导致DA神经元的死亡，SN内铁升高可使Str内DA释放量和含量均降低，因此铁含量的增加可能是DA含量减少的原因之一，铁离子螯合剂甲磺酸去铁胺具有保护DA神经元的作用。

This study is aimed to address the question whether the early discharges can affect thesilent period and modulate the late discharges and to investigate the possiblerole of dysfunction of primary myelinated afferents in generation of chronicpain. In addition, we also investigate the effect of the precedingA-conditioning stimuli with graded numbers on the late discharges of WDRneurons evoked by a following nociceptive test stimulus that activates bothA- and C-fibers.

在定义WDR神经元的反应特性时，通常用一个短促的电刺激刺激相关的神经干，激活A及C类纤维，这时可记录到一个反映有髓纤维传入的高频短促的早成分放电，接着是一个无放电的宁静期，最后是C纤维激活所诱发的晚成分放电，这种放电形式有别于脊髓背角的其它神经元。

In addition, we also investigate the effect of the precedingA-conditioning stimuli with graded numbers on the late discharges of WDRneurons evoked by a following nociceptive test stimulus that activates bothA- and C-fibers. WDR neurons located in the lumbar enlargement of the spinal cord are recorded with glass microelectrodes in regular electrophysiological techniques.

同时，检查了功能正常的动物，预先给予A纤维条件刺激对随后的伤害性刺激所诱发的WDR神经元的晚成分放电的影响，最后，我们估价了WDR神经元在慢性痛形成和维持过程中的重要作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。