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Research suggests that the primary hypothalamic perturbation in the HPA axis in depression might consist of increased numbers of CRF-containing neurons and CRF mRNA in the paraventricular nucleus, which leads to hypersecretion of hypothalamic CRF.

一些研究提示,抑郁症患者HPA轴中下丘脑的原发性功能紊乱包括室旁核中CRF神经元和CRF mRNA数量的增加,这将导致下丘脑CRF的过度分泌。

Immunohistochemistry method was used to detect the effect of Subdiaphragmatic vagotomy on hypertonicity activated neurons and astrocytes in SON and NTS.

应用免疫组织化学方法光镜下观察膈下切断迷走神经对腹腔给予高渗刺激引起大鼠NTS、SON内AST和神经元的影响。

We have used our anti-MNTF monoclonal antibody and MNTF-anti- idiotypic monoclonal antibody (MNTF-Id-McAb) to study the changes in localization and quantities of MNTF and its receptor in tongue muscles of 30 adult rats after 4 days, 2, 3 and 5 weeks, and 2 and 5 months of post-denervation of the hypoglossal nerve.

用本实验室制备的运动神经元诱向因子单克隆抗体和与其受体能特异结合的MNTF抗独特型单抗(MNTF-Id-McAb),对切断一侧舌下神经的30只大鼠舌内肌,分别在手术后4d,2周、3周和5周以及2个月和5个月,检测其MNTF和MNTF受体定位和含量的变化。

The inspiratory neurons were identified by their on-going activities that were correlated with RRDA of the hypoglossal nerve.

待稳定记录到吸气神经元的放电活动后,先以10μmol/L Gly灌流脑片20 min,洗脱Gly,待放电基本恢复后,再以1μmol/L STR灌流20min。

Objective To observe the response and relationship between astrocytes and neurons to hypotension rats.

目的 观察大鼠血压降低后脑内星形胶质细胞和神经元的反应及其相互关系。

Results Expression of orexin mRNA was located in nucleus of hypothalamic neuron.

结果:下丘脑神经元细胞细胞核中有orexin的mRNA表达。

OBJECTIVE: To probe into the regulatory effects of CRH on CREB secretion in hypothalamic neurons.

目的:探讨促肾上腺皮质激素释放激素对下丘脑神经元内CREB含量变化的调节作用。

For the first time, STAT3 protein phosphoiylation were found by the cultured hypothalamic cells with Leptin administration in vitro.

重组Leptin干预可以影响培养的下丘脑神经元中STAT3磷酸化蛋白的表达,并增强其活性。

It suggests that CRH may play a vital role in hypothalamic neuronal activation.

说明在调节下丘脑神经元激活过程中促肾上腺皮质激素释放激素可能起了重要的作用。

In control group, the expression of STAT3 protein in cultured hypothalamic cell was positive, but phospho-STAT3 protein expression was negative.

Leptin干预24 h后,培养下丘脑神经元的胞核和胞浆内均有磷酸化STAT3蛋白的表达,呈棕黄色。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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