神经元

Objective To investigate the response of neurons and astrocytesfrom Sprague Dawley rat brain against tert-buty1 hydroperoxide toxicity,both separately and in cooperation, for the purpose of exploring the interrelation of the two kinds of cells.

目的研究混合培养脑神经元与星形神经胶质细胞对活性氧叔丁基脂氢过氧化物的应激性，以探讨神经元与星形神经胶质细胞的相互作用。

Results: On day 12～ 18, rats were paralyzed on its 2 hind limbs, the coronal sections of lumbosacral enlargement of spinal cord with HE stainning showed that there were dilated capillaries, perivascular oversleeve-like inflammatory infilltration and anterior-horn motor-neuron hydropic degeneration.

结果：在接种后12～18天，大鼠出现双后肢瘫，脊髓横切片HE染色可见血管周围袖套样炎性细胞浸润和前角运动神经元肿胀变性。

A neuron in the network produces its output by processing the net input through an activation jfunction f, such as the tangent hyperbolic function chosen in this study as below

在网络里的神经元产生它的生产透过透过活动j处理网输入功能f，例如切线在这研究内选择如下的双曲线功能

Thissuggests that the loss of ICa previously demonstrated in injuredsensory neurons contributes to their dysfunction and hyperexcitability,and may lead to neuropathic pain.

这说明，损伤的感觉神经元中内向钙电流的降低会引发其功能障碍和过度兴奋，并可能导致神经性疼痛。

Hyperexcitability of neurons plays a critical role in the generation of neuropathic pain, and appears to be intimately linked to the plasticity of voltage - gated sodium channel subunits.

大量研究表明，神经元的异常兴奋是神经性疼痛产生的主要原因之一，并且这种异常兴奋与钠离子通道亚单位的可塑性有关。

Fromthis, we predicted that increasing ICa in injured neurons shouldcorrect their hyperexcitability.

基于此，我们预见增加损伤神经元的 ICa 可以纠正其高兴奋状态

GABA interneurons relatively resist ischemia-reperfusion injury,and the increasing expression of GAD65 in 3 d after ischemia-reperfusion can be a compensatory mechanism to reduce the hyperexcitability associated with ischemia-reperfusion.

GABA能中间神经元对缺血相对耐受；全脑缺血-再灌注3天，GAD65的表达增多可能是代偿性的机制，以减轻脑缺血后的高兴奋性。

These findings indicate that at least a part ofthe hyperexcitability of somatic sensory neurons after axotomyis attributable to diminished inward Ca2+ flux, and that measuresto restore ICa may potentially be therapeutic for painful peripheralneuropathy.

这些发现表明，轴索显微外科术后机体感觉神经元的过度兴奋和 Ca2+内流减少有关，修复 ICa 的措施可以用来治疗周围神经病引起的疼痛。

It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病（Parkinson's disease，PD）为神经系统变性疾病，主要的病理改变是黑质纹状体通路的多巴胺能神经元变性，导致多巴胺减少和乙酰胆碱系统功能亢进。

Parkinson's disease is a common neurodegenerative disease, which mainly affect the old age, characterized by tremor, muscle rigidity, bradykinesia and postural instability. It is caused by the degeneration of nigro-striatum dopaminergic neuron resulting in the reduction of dopamine and the hyperfunction of acetylcholine.

帕金森病（Parkinson's disease，PD）为神经系统变性疾病，主要的病理改变是黑质纹状体通路的多巴胺能神经元变性，导致多巴胺减少和乙酰胆碱系统功能亢进。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。