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Objective To study the relationship between the metabolism of glutamate in hippocampus neurons and the pathogenesis of epilepsy.

摘 要 目的:研究神经元谷氨酸合成、分解和分泌与癫痫发病的关系。

Methods The changes of NOS neuron of mouse brain in proconditioning to hypoxia were detected by histochemistry method.

采用组化法测定小鼠脑内一氧化氮合酶神经元在缺氧(1次缺氧,4次缺氧)预适应中的变化。

The expression pattern of PKC and morphology were investigated during inflammatory pain using immunocytochemistry and histochemistry.

应用组织化学和免疫细胞化学方法观察炎性痛过程中海马神经元形态学变化和PKC活性的改变。

Under transmission electron microscope, cellular swelling in brain tissue, nuclear membrane of neuron has incisures, some chromatic agglutination, group A mainly appears endoplasmic reticulum distention and glial cell endocytosis, while group B mainly appears histolysis; cardiac fibrous structure is chaotic, Z line concentrates, mitochondria swelling, nucleus deform; the ecphyma of podocyte becomes thinner and longer like villus, some mix together, plasma membrane infolding of renal cells decreases, mitochondria malformation, cells in lumens.

透射电镜观察显示,试验组动物脑组织细胞肿胀,神经元核膜出现切迹,部分染色质凝集,A组动物出现内质网扩张及胶质细胞吞噬现象,B组动物以组织溶解为主;心肌纤维结构紊乱,Z线聚集,收缩带形成,线粒体肿胀,核变形;肾小球足突细长,绒毛化,并可见足突融合,肾小管上皮细胞质膜内褶减少,线粒体畸形,管腔可见脱落细胞,上述改变均以B组为著。

Then, we give some basic information about the neuron model we studied which given by Hodgkin and Huxley.

然后,我们给出所研究的模型—Hodgkin-Huxley神经元模型的一些基本知识。

RESULTS: hMSC had good homogeneousness and immunological reaction after implantation.

结果: 第5代呈集落生长的hMSC,均一性好。hMSC可在脑内存活6周以上;随着时间的延长,hMSC在脑内迁移的范围越来越大;间接免疫荧光表明hMSC在大鼠脑内表达人神经元特异性烯醇化酶、神经丝蛋白和胶质纤维酸性蛋白;模型鼠的肢体运动功能有明显改善。

The effects could be attributed to the selective action of BmK Ⅰ on the TTX-S Na〓 channel: slowing the inactivation process of Na〓 channel, increasing the amplitude of peak Na〓 currents; 2 BmK abT, a new-type neurotoxin with higher sequence homology to β-type scorpion neurotoxin, was found to slow the inactivation process of Na〓 channel and prolong the duration of action potential in DRG neurons.

这些结果提示BmK IT2和BmK AS-1的外周抗伤害性效应可能是通过它们对小直径DRG神经元外周游离末梢即C纤维末梢上的TTX-S和TTX-R钠通道的门控调节所致,且BmK IT2对角叉菜胶致炎大鼠较强的抗伤害性作用可能是由于它对TTX-R钠通道较高的敏感性所致。二。特异性钠通道调制剂-东亚钳蝎神经毒素的电生理特征。

Every group was fed with Hup A, Kangnaoshuai and DR. The ability of learning memory was measured by Morris water maze.

运用MORRIS水迷宫检测各组大鼠的学习记忆能力及采用免疫组化方法观察各组大鼠海马神经元TNFα,IL1α蛋白的变化。

The results demonstrate that HupA, like tacrine, inhibits voltage gated potassium channels in rat hippocampal pyramidal neurons.

上述结果表明,石杉碱甲主要抑制海马锥体神经元的两种电压门控性钾通道。

With 70 years of separating us from the publication of this book, we can see that Huxley's

我们所知道的最为复杂的东西。人脑的重量为3 磅,而这3 磅却包含着100亿个神经元和1000

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。