神经元

Expression of NR1 subunit on cultured cerebral cortical neurons of fetal rats has developmental changes, which is related to neuronic maturity.

体外原代培养的胎鼠大脑皮层神经元NR1亚基有发育性变化，这种变化与神经元的成熟度有关。

Moutains of evidences from laboratary and clinical data show that gene abnormality is the major etiological factor of over 40% patients affected with epilepsy.There were also 6 epilepsy genes been cloned successfully, and mutations of over 1000 genes maybe related to epilepsy. These abnormal genes influence many aspects from molecular level to the neuronal plasticity, such as the development of brain,neuronic degeneration, remodeling of neural circuits, energy metabolism, ion channel and so on.These factors would at last affect the formation of epilepsy focus, propagations of epileptic potentials, vulnerability of epilepsy cells.

大量的实验和临床资料提示基因异常是40%以上癫痫患者的病因，有6种常见全身癫痫的基因已被成功克隆，1000种以上的基因突变可能与癫痫的发作有关，这些表达异常的基因分布在脑发育、神经元变性及神经环路重组、能量代谢、离子通道等多个环节，从分子、细胞、神经元可塑性等多个方面影响着癫痫灶的形成、痫性放电的扩布及癫痫细胞的损伤，构成了癫痫的基因机制。

Methods Adopting electrophysiological methods, the extracellular discharge signals of neuronic action in NTS were recorded with glass microelectrode. The influence of the discharges of NTS neurons and gastric pressure responding to the acupuncture at "Zusanli" point were observed in normal status and the condition of Atropine or Metoclopramide intravenous injection.

采用神经电生理学方法，用微电极细胞外记录大鼠孤束核单个神经元的活动，在正常生理状态下及经血管注射抑制胃运动的药物阿托品或促进胃运动的药物胃复安后，观察针刺&足三里&对孤束核神经元放电及胃内压的影响。

Methods: Adopting electrophysiological methods, the extracellular discharge signals of neuronic action in NTS were recorded with glass microelectrode. The influence of the discharges of NTS neurons responding to the acupuncture at "Zusanli","Neiguan","Zhongwan","Qihai" point were observed in rats' normal status and the condition of intravenous injection Atropine.

采用神经电生理学方法，用微电极细胞外记录大鼠孤束核单个神经元的活动，在正常生理状态下及经血管注射抑制胃运动的药物阿托品后，观察针刺&足三里&、&内关&、&中脘&、&气海&对孤束核神经元放电的影响。

Methods Adopting electrophysiological methods,the extracellular discharge signals of neuronic action in NTS were recorded with glass microelectrodes. The effects of acupuncture at "Zusanli"(ST 36),"Neiguan"(PC 6),"Zhongwan"(CV 12),"Qihai"(CV 6) on discharges of NTS neurons and intra-gastric pressure were observed in the rat at normal physiological state,and increase or reduction of gastric motility.

采用神经电生理学方法，用微电极细胞外记录大鼠孤束核单个神经元的活动，观察在正常生理状态及胃运动增强和胃运动抑制的病理状态下，分别针刺&足三里&&内关&&中脘&&气海&对孤束核神经元放电及胃内压的影响。

Nerve grows factor and brain-derived neurotropic factor, as one of the important active molecules, belong to neurotrophic family, which can affect the development of neuron and prevent neuron from damage.

神经生长因子（Nerve grows factor，NGF）和脑源性神经生长因子(Brain-derived neurotropic factor，BDNF)属于神经营养素家族，是神经系统重要的活性分子之一，是中枢神经系统胆碱能神经元、周围神经系统交感神经元及感觉神经元发育、分化、功能活动必不可少的营养分子。

Among 24 excitatory neurons of NRM, the spontaneous discharges of most of them were obviously enhanced by nociceptive stimulation.

在24例兴奋型神经元中，刺激尾核头部能够激活大多数NRM神经元的自发放电和抑制其伤害感受性反应。

We tested the possibility of selectively blocking the excitability of primary sensory nociceptor (pain-sensing) neurons by introducing the charged, membrane-impermeant lidocaine derivative QX-314 through the pore of the noxious-heat-sensitive TRPV1 channel.

一种阻断特定痛觉神经元的这种活性而又不影响其他感觉或运动神经元的方法，也许可用来创建一种目标性更强的局部麻醉方法，而这正是Binshtok等人在本期Nature上提出的一个观点。

Almost no neurons in the deprived layers responded to the drifting sinusoidal gratings to the nondominant eyes, while half of the neurons in the non-deprived layers did.

但是，与非剥夺层神经元相比，几乎没有剥夺层的神经元能对非优势眼的正弦移动光栅刺激起反应，并受其空间频率的调制。

They include cerebellum,cerebral cortex,hypothalamus, mesencephalon, and pons.A few of positive cells could be seen in the medulla oblongata. NADPH-d positive neurons appears blue.Their shapes were diversform such as polygon,fusiform,nummular and oval etc. Karyon hasn't pigmentation. Dendriate and axon's pigmentation are clear.

实验一利用NADPH-d酶组织化学技术，对NOS阳性神经元在兔脑的总体分布规律及其衰老性变化进行了系统研究，结果表明：①NADPH-d阳性神经元分布于兔脑各个部位，几乎涉及所有区域：包括小脑、大脑皮质、丘脑下部、中脑、脑桥和小脑，而延髓分布较少。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。