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To explore the characteristics and significances of ATP-activated currents in rat different primary sensory neurons, the experiments were performed on neurons freshly isolated from rat dorsal root ganglion, trigeminal ganglion and nodose ganglion using whole-cell patch-clamp .

为探讨大鼠不同初级感觉神经元ATP-激活电流的电生理学特征及意义,本实验在新鲜分离的大鼠三种初级感觉神经元标本上,应用全细胞膜片钳技术记录,对外加ATP引起的膜电流的变化进行了研究。

After treatment of CCl4 through oral route for four weeks, we have observed an interesting phenomenon in the animal model. That is the significantly decreased condition of nitric oxide synthase. The locations are sympathetic T7-T10 dorsal root ganglion, T7-T10 intermediolateral cell column, celiac ganglion, parasympathetic nodose ganglion, solitary tract nucleus, and dorsal motor vagal nucleus.

结果显示:在餵食四氯化碳四周起,其交感神经回路上的T7-T10背根神经节、T7-T10脊髓侧角中间外侧细胞柱之交感节前神经元以及位於腹腔神经节的交感节后神经元所含之一氧化氮合成下降;而副交感神经回路上的小结神经节、孤立径核以及迷走神经背侧运动核所含之一氧化氮合成亦下降。

The results are indicated that only the strength of gap junction is large enough, can the abnormal oscillation propagate to synchronize the other neurons around and the process is chaotic and complex;the nonlinear and complexity of the oscillations with strong strength of gap junction are larger than that of oscillation with weak strength of gap junction.

结果表明:只有电突触耦合达到一定强度时,异常振荡才能传导并引起神经元的同步振荡;传导活动是混沌和复杂的;在突触耦合强度较强时的神经元活动的非线性和复杂性要强于其在突触强度较弱时的。

Methods The influence of DA on the electric activity of the pain-excited neuron in the caudate nucleus of normal rats or morphinistic rats was recorded after the sciatic nerve was noxiously stimulated.

在给予坐骨神经伤害性刺激后,记录中枢痛兴奋神经元的电活动,观察多巴胺对正常大鼠和吗啡成瘾大鼠中枢痛兴奋神经元电活动的影响。

However, since Barrington's nucleus contained not only projection neurons to the lumbosacral spinal cord, but also those to the nucleus of the solitary tract and thalamus, and dendrites of neurons located in its surrounding nuclei extend into the nucleus.

然而,由于 Barrington's 核的核区内包含有临近核团神经元的树突,同时还含有投射到孤束核和丘脑的投射神经元

FasL immunopositive neurons were observed in cerebral cortex, especially in pyramidal neurons of lamina Ⅱ and Ⅴ, cerebellar nuclei, diencephalon, and brain stem nuclei involving pontine nucleus, vestibular nucleus, cochlear nucleus, spinal nucleus of trigeminal nerve, hypoglossal nucleus, nucleus ambiguous and reticular formation.

间脑中有FasL阳性神经元分布。在脑干,Fas主要分布于前庭神经核、迷走神经背核和三叉神经脊束核的神经元;FasL广泛分布在脑桥核、前庭神经核、三叉神经脊束核、舌下神经核、蜗神经核、网状结构和疑核。

Intensely and densely stained PKC_γimmunoreactive neurons were mainly observed in the cerebral cortex, hippocampus,amygdaloid complex,cerebellar cortex,ventral and dorsal cochlear nuclei,caudal spinal trigeminal nucleus and spinal dorsal horns.

研究发现PKCγ阳性神经元广泛分布于大鼠神经系统,密集、浓染的PKCγ阳性神经元主要见于大脑皮质、海马、杏仁复合体、小脑皮质、耳蜗腹侧核和耳蜗背侧核。

NYA can promote the differention from NSC to neuron, and survival.

脑溢安可促进神经干细胞向神经元方向分化,提高神经干细胞分化为神经元的比率,并具有促进神经细胞存活的作用。

Objective:To explore the signaling transduction of CCK8 in mice neurons by proteomics methods.Methods:Cultured neurons were labled with [32P]orthophosphate (2.03×105Bq/ml) for 2h in 5%CO2 at 37℃. DMEM and CCK8 (10-7mol/L) were added to respectively for 0, 5, 20, 60 and 120min.

目的:通过应用蛋白质组学的方法与技术,对八肽胆囊收缩素(octapeptite cholecystokinin, CCK8)作用于乳小鼠皮质神经元后蛋白质磷酸化状态进行分析,为初步探讨胆囊收缩素在皮质神经元中的信号转导途径提供依据。

These cells can recover after a single exposure, but if you overexpose them often enough, they end up dying, and you lose that functional ability inside your inner ear. The cells that die are not replaceable.

这些神经元经过一次照射治疗后会恢复功能,但是如果你依然像以前一样让它们操劳过度,它们最终会死掉,并且你的内耳将会失去那些听力功能,这些神经元一旦死掉是无法替代的。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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