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The morphology, size and signal of nerve root, nerve ganglion, nerve trunk and femoral nerve, were observed. The brachyaxis and nerve-muscle signal ratio of right L4 nerve root, nerve gatiglion and nerve trunk were measured.

正常组观测腰2~5神经根、神经节及神经干、股神经的形态、大小及信号;GBS及CIDP组观察神经及其周围的改变,测量右侧腰4神经根、神经节、神经干及股神经的短轴径线及神经肌肉信号比。

Neuroectoderm; neural crest; neural plate; floor plate; neural tube; neuraxis; neurulation; neuroblasts; stem cells; differentiation; ontogeny; morphogenesis; histogenesis; organogenesis; synaptogenesis; gangliogenesis; embryogenesis; axonogenesis; retinogenesis; gliogenesis; glial progenitor cells; oligodendrocyte progenitor cells; retinal progenitor cells; nerve growth factor; neurotrophic factors; trophic factors; growth factors; neural tube defects; anencephaly; spina bifida; neuroblastoma cells; cell migration; neurogenesis; development; developmental stages

神经外胚层;神经脊;神经板;底板;神经管;轴索;神经胚形成;成神经细胞;干细胞;分化;个体发生;形态发生;组织发生;器官发生;突触发生;gangliogenesis;胚胎发生;axonogenesis;retinogenesis;gliogenesis;神经胶质祖细胞;少突神经胶质细胞祖细胞;视网膜祖细胞;神经生长因子;神经营养因子;营养因子;生长因素;神经管故障;无脑;脊柱裂;成神经细胞瘤细胞;细胞迁移;神经发生;发展;发展进程首页上一页下一页末页共有 22 条记录,本页从第 11 到第 20 条。

This conference is held by The Chinese Congress of Neurological Surgeons, the Editorial Committees of Chinese Journal of Neurosurgery, Chinese Journal of Minimally Invasive Neurosurgery, Chinese Journal of Neuro-oncology and Chinese Journal of Neurosurgical Disease Research. The Neurosurgical Sodality of the 3 Northeast Provinces and Neurosurgical Institution of Harbin Medical University (The Department of Neurosurgery of the First Clinical College of Harbin Medical University) are the organizers of the conference.

本次大会是由中国医师协会神经外科医师分会主办、有《中华神经外科杂志》编委会、《中国微侵袭神经外科杂志》编委会、《中国神经肿瘤杂志》编委会、《中华神经外科疾病研究杂志》编委会等参与,由东北三省神经外科医师联谊会和哈尔滨医科大学神经外科研究所暨第一附属医院神经外科承办。

In group A, the medial antebrachial cutaneous nerve was cut 5 mm away from its origin and its proximal end was anastomozed end-to-end to the distal end of musculocutaneous nerve. In group B, the musculocutaneous nerve was cut 5 mm away from its nerve entry point and the proximal end of medial antebrachial cutaneous nerve were anastomozed end-to-end to the distal end of musculocutaneous nerve. In group C, medial antebrachial cutaneous nerve and musculocutaneous nerve were cut, without further anastomosis.

每组大鼠左上肢制备实验模型,右上肢为正常对照,不作任何处理。A组:于距前臂内侧皮神经起点5 mm 处切断该神经,将其近端与切断的肌皮神经远端行无张力端端吻合;B 组:于距肌皮神经入肌点5 mm 处切断该神经,将其远端与切断的前臂内侧皮神经近端行无张力的端端吻合;C 组:切断肌皮神经和前臂内侧皮神经后不予吻合,形成肱二头肌失神经支配模型。

For those in control group (n=14), the animals did not undergo any surgery of the nerve fibers and ganglia. In Vi group (n=9), the animals underwent bilateral resection of the nasociliary and postganglionic parasympathetic nerve fibbers. In SCG group (n=8), the animals underwent bilateral resection of supper cervical ganglia. In V1+SCG group (n=9), the animals underwent both surgeries as Vi and SCG group did. In sham operation group (n=11), the animals underwent carotid manipulation with blunt-tipped forceps as well as dissection of nasociliary and postganglionic parasympathetic nerve fibers around the ethmoidal foramen, without cutting any nerves. SCS was performed on rats and CBF was monitored by laser Doppler flowmeter recordings.

SD大鼠分5组:对照组(n=14,不对神经纤维和神经节作任何手术处理)、V1组(n=9,切断双侧鼻睫状神经及其副交感节后纤维)、SCG组(n=8,切断双侧颈上神经节)、V1+SCG组(n=9,切断双侧鼻睫状神经及其副交感节后纤维和双侧颈上神经节)、假手术组(n=11,手术暴露双侧鼻睫状神经及其副交感节后纤维和双侧颈上神经节,但不切断神经纤维或神经节);给予大鼠SCS,并用激光多普勒实时记录脑血流。

Control group, the animal underwent SCS and LDF recordings without any surgery of the nerve fibers and ganglia. V1 group, the animal underwent bilateral resection of the nasociliary and post-ganglionic parasympathetic nerve fibbers. SCG group, the animal underwent bilateral resection of supper cervical ganglion. V1 + SCG group, the animal underwent both surgeries as V1- and SCG-group animals did. Sham group, the animal underwent the carotid manipulation with blunt-tipped forceps as well as the dissection of nasociliary and post-ganglionic parasympathetic nerve fibers around the ethmoidal foramen, but without cutting any nerves.

动物分成5组,对照组:不对神经纤维和神经节作任何手术处理;V1组:切断双侧鼻睫状神经及其副交感节后纤维;SCS组:切断双侧颈上神经节;V1+SCG:切断双侧鼻睫状神经及其副交感节后纤维及双侧颈上神经节;假手术组:手术暴露双侧鼻睫状神经和其副交感节后纤维及双侧颈上神经节,但不切断神经纤维或神经节。

Neuroectoderm; neural crest; neural plate; floor plate; neural tube; neuraxis; neurulation; neuroblasts; stem cells; differentiation; ontogeny; morphogenesis; histogenesis; organogenesis; synaptogenesis; gangliogenesis; embryogenesis; axonogenesis; retinogenesis; gliogenesis; glial progenitor cells; oligodendrocyte progenitor cells; retinal progenitor cells; nerve growth factor; neurotrophic factors; trophic factors; growth factors; neural tube defects; anencephaly; spina bifida; neuroblastoma cells; cell migration; neurogenesis; development; developmental stages

神经外胚层;神经脊;神经板;底板;神经管;轴索;神经胚形成;成神经细胞;干细胞;分化;个体发生;形态发生;组织发生;器官发生;突触发生;gangliogenesis;胚胎发生;axonogenesis;retinogenesis;gliogenesis;神经胶质祖细胞;少突神经胶质细胞祖细胞;视网膜祖细胞;神经生长因子;神经营养因子;营养因子;生长因素;神经管故障;无脑;脊柱裂;成神经细胞瘤细胞;细胞迁移;神经发生;发展;发展进程下一页末页共有 23 条记录,本页从第 1 到第 10 条。

Before transecting inject 1ml Sodium Chloride in the epineurium. Annular tensile the proximal of epineurium with microscopic forceps annular shear the epineurium 7mm before broken ends with microscopic shear and stretch the epineurium until the two ends distance is 5mm.Use 8-0 suture line to bridge the nerve gap and make a 5 mm nerve tube at the proximal nerve end. Interrupted suture the epineurium tube and the distal nerve end make a 5 mm nerve mamuro for the injury nerve.Results: Postperative observation lasted for 6 weeks regeneration nerve through the 5 mm nerve mamuro.

在大鼠的坐骨神经距股方肌下缘15mm处,用1ml注射器向神经外膜下注入1ml生理盐水,然后于此处切断坐骨神经,用显微镊环形拉伸近端神经外膜,在距断端约7mm处用显微剪环形剪开神经外膜,并继续拉伸外膜使外膜两断端间距约5mm停止,用8-0的无损伤缝线桥接神经外膜两端,在神经近端形成约5mm的神经外膜管,将神经外膜管与神经远端间断缝合,使断伤的神经束间留有5mm的小间室。

In group A, the left musculocutaneous nerve was transected to make the model of biceps brachii denervation and anastomosed to its proximal end 6 weeks later; In group B, the musculocutaneous nerve was transected and the distal end was coapted to the purely motor medial pectoral nerve immediately and the musculocutaneous nerve was separated from the medial pectoral nerve, and reanastomosed to its proximal end 6 weeks later.

随机分为两组( n =8):肌皮神经延期修复组,单纯剪断左侧肌皮神经,造成肱二头肌失神经支配模型,6 周后行肌皮神经修复;神经移位寄养二期肌皮神经修复组,剪断左侧肌皮神经后即刻将胸内侧神经分支的近端移位寄养于肌皮神经的远端,6 周后结束寄养关系行二期神经修复术。

objective the aim of this study is to investigate the expression and the distribution of the nerve growth factor during the period of neural tube development of human embryo.method early development of neural tube was studied in human embryos about 35 gestational days by using immunocytochemical abc technique.result there were ngf immuno-positive substances in the cytoplasm and nuclei of neuroepithelial cells in the ventricular zones of neural tube.in the intermediate zone of neural tube,ngf immunoreactivity was detected in the nuclei of some neurons,or the processes of other neurons which contained no ngf-immunoreactive substances in their nuclei;the expression pattern of ngf in the marginal zone of neural tube was similar to that of the intermediate zone.the density of ngf-immunorecative particles was higher on the rostrum side of neural tube than on the caudal side.the ngf immuno-positive cells were also observed among the somites of embryo under the neural tube.conclusion these results suggest that ngf was an important signal molecule to induce neural tube differentiation,and that ngf may play a significant role in regulation of the biological function of neurons in developing neural tube.

目的 研究捷安肽素的抗真菌作用机理。方法采用形态学方法和同位素标记法。显微形态观察经捷安肽素处理后的供试真菌的形态学变化。进一步采用14c同位素标记的特异底物&尿苷二磷酸-(14c)-葡萄糖&示踪,研究捷安肽素对真菌(1,3)-β-d-葡聚糖合成酶活性反应的影响。结果研究神经生长因子在早期人胚神经管发育过程中的定位表达。方法采用免疫细胞化学 abc法染色,研究35天人胚的发育情况。结果在人胚神经管的室管带中,神经元的细胞质和细胞核ngf免疫反应阳性;在中间带,一部分神经元的细胞核ngf免疫反应阳性,另外一部分神经元的细胞核ngf免疫反应阴性,而其突起ngf免疫反应阳性;在边缘带ngf的表达与中间带相似。在神经管的头侧ngf阳性反应较强,神经管的尾侧ngf阳性反应较弱。结论 ngf在人胚神经管免疫反应阳性,表明ngf可能是诱导神经管分化发育的重要信号分子,提示ngf可能在人胚神经管的发育中具有十分重要的作用。神经生长因子;人胚;神经管;发育

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