磺酰胺

Four new chiral sulfonamide alcohol s were synthesized from camphor and L-phenylalanine and their application to the enantioselective addition of diethylzinc to benzaldehyde was described.

由天然樟脑和-苯丙氨酸合成了4个新的手性磺酰胺醇，并对其在二乙基锌对苯甲醛的不对称加成中的催化性能进行了研究。

Four new chiral sulfonamide alcohols were synthesized from camphor and L-phenylalanine and their application to the enantioselective addition of diethylzinc to benzaldehyde was described.

由天然樟脑和-苯丙氨酸合成了4个新的手性磺酰胺醇，并对其在二乙基锌对苯甲醛的不对称加成中的催化性能进行了研究。

Methyl-4-aminobenzyl sulfonamide, a key intermediate for synthesis of the pharmaceutical substance Sumatriptan, was prepared throught four steps.

甲基 4 氨基苯甲基磺酰胺是一种重要的医药中间体，主要用于合成药物舒马普坦。

The N-alkylation of N-monosubstituted sulfonamide s with alkyl halides promoted by KF using ionic liquids as reaction media was reported in this paper.

报道了KF作用下离子液体介质中N-单取代磺酰胺和卤代烃的N-烷基化反应，考察了4种不同结构的离子液体BF4、BF4和PF6对反应的影响。

In this chapter, we report the synthesis of an alkyl imidazo lium salt supported chiral sulfonamide ligand and its use and recycling in enantiosel-ective reduction of prochiral ketones to optically active secondary alcohols.

在这里我们报道了一种离子液体接枝的磺酰胺手性配体以及在前手性酮的不对称还原反应中的应用，获得了较好的对映纯过量，实现了手性配体的回收和重复使用。

The preparation of a novel chiral sulfonamide alcohol derived from natural camphor and its application in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to benzaldehyde is described.

由天然樟脑合成了一个新手性磺酰胺醇，并对其在二乙基锌对苯甲醛的对映选择性加成中的催化性能进行了研究，获得了73%化学产率和

The invention belongs to the synthesis technical field of pharmaceutical intermediates, and more particularly relates to a preparation method of Cis-4-(2-bromine ethylene) benzene sulfonamide.

本发明属于药物中间体合成技术领域，具体涉及一种顺式-4-(2-溴乙烯基)苯磺酰胺的制备方法。

As to the P—methylbenzene sulfonamide plasticizer, less than 10% is needed to meet the requirement of brittle— toughness transition. Whereas, for butyl P—hydroxybenaoate, 20% is needed for the plasticate system to reach the brittle—toughness transition.

对于苯磺酰胺增塑剂，只需不足10％的用量就达到脆—韧转变，而苯甲酸酯类增塑体系则需要20％的用量才能达到脆—韧转变。

Started from D-tyrosine, we obtained the tetramic acid 96 using Jouin reaction. The assembly of the second fragment 109 was stared from 1,4-butandiol,using asymmetric alkylation reaction developed by Oppolzer as a key step. Coupling of the tetramic acid 96 with 109 provided the key intermediate 110 according to Yoshii\'s procedure. After remove protective group and Sharpless epoxidation, we obtained the key intermediate 113. Its macrocyclization to form the final product is in progress.

本论文的第二章主要对Macrocidin A开展了合成工作，我们从D构型的酪氨酸出发，经过官能团转换；利用Jouin反应生成Tetramic acid 96，另外一个片断从1，4-丁二醇开始经过多步反应生成碘化物104，利用Oppolzer发展的手性樟脑磺酰胺为辅基参与的不对称烷基化反应，引入手性甲基，生成关键中间体109，接着通过Yoshii发展的方法连接96和109生成110，经过Sharpless不对称环氧化反应建立环氧化合物，然后脱去保护基得到关环前体113，分子内的Mitsunobu反应进行关大环反应正在进行之中。

And then the intermolecular reductive cyclization reaction of N,N-diethyl-o-nitrobenzenesulfonamide with nitriles promoted by samarium diiodide was studied. 2H-1,2,4-Benzothiadiazine 1,1-Dioxides were prepared in good yields under mild and neutral conditions.

然后研究了二碘化钐促进的邻硝基N，N-二乙基苯磺酰胺与腈发生的分子间交叉还原偶联反应，一步合成了2H-1，2，4-苯并噻二嗪-1，1-二氧化物。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。