磺胺的

Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%~97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, cefazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72.2%, 85.9%, 100.0% and 100.0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%.

结果：革兰阴性杆菌比例显著升高，条件致病菌和酵母样真菌检出机会显著增多；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和枸橼酸杆菌等革兰阴性杆菌对喹诺酮类药物的耐药率达57%~97%，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、头孢唑啉和氨苄西林的耐药率分别为40.9%、42.4%、63.6%、70.2%、85.9%、100.0%和100.0%；链球菌和肠球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物均呈高度耐药，耐药率在36%~100%。

To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G－ bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50～97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果：G－杆菌比例居多，条件致病菌和酵母样真菌检出机会显著增高；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和克雷伯菌等G－杆菌对喹诺酮类药物的耐药率在50％～97.7％，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50％以上，链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

Sulfa drug s inhibit the growth and multiplication of certain bacteria by interfering with the synthesis of folic acid.

磺胺药通过干扰细菌的正常代谢和生长所需的系统来抑制细菌的生长和繁殖。

Sulfa drugs inhibit the growth and multiplication of certain bacteria by interfering with the synthesis of folic acid.

磺胺药通过干扰细菌的正常代谢和生长所需的系统来抑制细菌的生长和繁殖。

With this discovery,it was possible to embark on a program of synthesis based on the sulfanilamide structure,which yeilded a large number of active drugs with various medical uses.

随着这个发现，以磺胺结构为核心的合成加工过程是可行的，那就能产生多种医疗用途的药物。

The aim of the experiment was to correctly evaluate the effect of different concentrations of sulfaquinoxaline on the growth development and various organs of chicks, especially the immune organs.

目的］为了正确评价不同浓度的磺胺喹恶啉对雏鸡的生长发育和对各器官组织特别是免疫器官的影响，并分析其中毒机理。

From about July 1942 to about September 1943, experiments to investigate the effectiveness of sulfonamide, a synthetic antimicrobial agent, were conducted at Ravensbrück.

从1942年起到1943年9月，纳粹在Ravensbrück进行了检验研究磺胺类药物，一种人工合成的抗菌剂的有效性的实验。

Results: The 1034 strains of 8 types of pathogenetic aeromonase are sensitive to most of antibiotic and the highest resistance rate of 91.9% is ampicillin. The second one of 77.9% is piperacitlin and terramycin and sulfona mides are also with the high resistance rate of 62.4% and 56.9%. 127 strains (12.3%) which can produce the Ampc enzyme was found and 45 strains (4.4%) was multiple-drug resistance.

结果：8种1034株致病性气单胞菌对大多抗生素敏感，耐药率最高的是氨苄西林抗生素，达91.9%，哌拉西林次之，为77.9%，土霉素和磺胺类也有较高的耐药率，分别为62.4%和56.9%；检出具有产AmpC酶能力的致病性气单胞菌127株，占12.3%，多重耐药性菌株45株，占4.4%。

METHODS The minimal effective bactericidal concentration of 60 strains of Gram negative bacteria resistant to QACs was detected by diluting-counting method; the phenotype to QACs by the improved phenotype screening test, the qacE-sull gene of resistance to QACs and sulphonamide compounds by PCR.

方法使用稀释计数法测定60株革兰阴性杆菌对季胺盐复合物的最低有效杀菌浓度，利用改良的表型筛选试验检测耐QACs的表型，采用聚合酶链反应试验检测耐季铵盐消毒剂-磺胺复合物基因qacE-sul1。

Methods:The minimal effective bactericidal concentration of 60 strains Gram negative bacterium resistant to QACs were detected by diluting-counting method; the phenotype to QACs by the improved phenotype screening test,the qacE-sul1 gene of resistance to QACs and Sulphonamide Compou...

使用稀释计数法测定60株革兰阴性杆菌对季胺盐复合物的最低有效杀菌浓度，使用改良的表型筛选试验检测耐QACs的表型，使用聚合酶链反应试验检测耐季铵盐消毒剂-磺胺复合物基因qacE-sul1。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。