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磺胺噻唑

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The products include two series: Sulfa drugs Industrial Sulfanilamide, Crystel Sulfanilamide, Sulfaguanidine, Sulfadimidine(Sodium, Sulfadiazine, Sulfathiazole Sodium, Sulfaquinoxaline Sodium, Sulfameter Dimethyl Sulfate, Nitromethane, Hydroxylamine Hcl.

本公司专业生产化工、医药中间体,产品主要包括磺胺(工业磺胺、结晶磺胺、磺胺脒、磺胺二甲嘧啶、磺胺嘧啶、磺胺噻唑钠、磺胺喹噁啉钠、磺胺五甲氧嘧啶)及硫酸二甲酯(硫酸二甲酯、硝基甲烷、烟酸羟胺)两大系列。

Object: A specific and sensitive liquid chromatography tandem mass spectrometry method was developed for the multiresidue determination of sulfisomidine, sulfapyridine, sulfamerazine, sulfamethoxazole, sulfisoxazole, sulfadiazine, sulfamethizole, sulfachlorpyridazine, sulfamethoxypyridazine, sulfadimethoxine, sulfamonomethoxine, sulfathiazole, sulfadoxine, sulfaquinoxaline, sulfanilamide, sulfaguanidine, sulfamoxole, sulfameter, sulfadimidine, sulfacetamide, sulfaphenazole, sulfanitran, sulfabenzamide and a potentiator, trimethoprim, in meat.

目的:建立猪肉中磺胺及其增效剂多残留检测的液相色谱-串联质谱法,包括磺胺二甲异嘧啶、磺胺吡啶、磺胺甲基嘧啶、磺胺甲基异噁唑、磺胺二甲异噁唑、磺胺嘧啶、磺胺甲噻二唑、磺胺氯哒嗪、磺胺甲氧哒嗪、磺胺间二甲氧嘧啶、磺胺-6-甲氧嘧啶、磺胺噻唑、磺胺邻二甲氧嘧啶、磺胺喹噁啉、磺胺、磺胺脒、磺胺噁唑、磺胺甲氧嘧啶、磺胺二甲嘧啶、磺胺醋酰、磺胺苯吡唑、磺胺硝苯、磺胺苯酰和甲氧苄氨嘧啶。

A method for the determination of 12 sulfonamides (sulfanilamide, sulfamonomethoxine, sulfacetamide, sulfamethoxazole, sulfadiazine, sulfisoxazole, sulfathiazole, sulfadimethoxine, sulfamerazine, sulfaquinoxaline, sulfamethazine, sulfanitran) in cosmetics was developed by ultra performance liquid chromatography with photodiode array detector. The chromatographic column used was Acquity UPLCTM BEHC C18 (50 mm×2.1 mm, 1.7 μm) and the mobile phase was acetonitrile-0.1% formic acid aqueous solution.

建立了采用超高效液相色谱-二极管阵列检测器测定化妆品中12种常见的磺胺抗生素(磺胺,磺胺间甲氧嘧啶,磺胺醋酰,磺胺甲基异唑,磺胺嘧啶,磺胺二甲异唑,磺胺噻唑,磺胺二甲氧嘧啶,磺胺甲基嘧啶,磺胺喹啉,磺胺二甲嘧啶,磺胺硝苯)的方法。

Results: The linearity range for the determination was 10~1500 μg/L for sulfanilamide, 50~1500 μg/L for sulfathiazole, 10~1500 μg/L for sulfamethoxazole and 10~1500 μg/L for sulfamethazine.

结果:磺胺、磺胺噻唑、磺胺甲恶唑和磺胺甲嘧啶的线性范围分别是:10~1500μg/L、50~1500μg/L、10~1500μg/L、10~1500μg/L;检出限分别为:8.3、12、7.9、9.1μg/L;回收率为

Main products are PVC resin,Caustic Soda,Liquid Chlorine,Hydrochloric Acid,Sulfuric Acid,Chlorosulforic Acid, Sulfanilamide,Sulfadimidime and Sulfathiazole etc organic chemicals,inorganic chemicals and raw medicines more than 20 kinds of products,and total yield is more than 300 thousand tons.

主要产品有电石,聚氯乙烯,烧碱,液氯,盐酸,硫酸,氯磺酸,氨苯磺胺,磺胺噻唑等有机化工,无机化工,原料药等20多种产品,年总年量30多万吨。

Soda,Liquid Chlorine,Hydrochloric Acid,Sulfuric Acid,Chlorosulforic Acid, Sulfanilamide,Sulfadimidime and Sulfathiazole etc organic chemicals,inorganic chemicals and raw medicines more than 20 kinds of products,and total yield is more than 300 thousand tons.

主要产品有电石、聚氯乙烯、烧碱、液氯、盐酸、硫酸、氯磺酸、氨苯磺胺、磺胺噻唑等有机化工、无机化工、原料药等20多种产品,年总年量30多万吨。

A UPLC method was established for the ten sulfonamides including sulfadiazine,sulfathiazole,sulfadimidine(SM2),sulfamethoxypyridazine,sulfachlorpyridazine,sulfamonomethoxine, sulfamethoxazole, sulfachloropyrazine (Esb3),sulfadimethoxine and sulfaquinoxaline in pig muscle and milk.

建立了猪肉和牛奶中磺胺嘧啶、磺胺噻唑、磺胺二甲嘧啶(SM2)、磺胺甲氧嗪、磺胺氯哒嗪、磺胺间甲氧嘧啶、磺胺甲基异噁唑、磺胺氯吡嗪(Esb3)、磺胺地索辛和磺胺喹噁啉共10种磺胺类药物残留检测的超高效液相色谱法。

The spectra characteristics of interaction between sulfathiazole and bovine serum albumin was studied by fluorescence quenching and synchronous fluorescence techniques at 21℃ and 29℃.

分别研究了21℃和29℃时,磺胺噻唑与牛血清白蛋白作用的荧光猝灭光谱和同步荧光光谱特征。

Sulfa drugs, such as cotrimoxazole, isoxazole sulfonamides, sulfa Micronesia acridine, Sulfamethoxazole, Sulfonamides methoxy pyrazine, sulfonamides Formamidine, probenecid, double pyrimidine films, bacteriostatic sulfonamide, trimethoprim, sulfathiazole, such as amber.

磺胺类药物,如复方新诺明、磺胺异恶唑、磺胺密啶、磺胺甲基异恶唑、磺胺甲氧吡嗪、磺胺脒、丙磺舒、双嘧啶片、制菌磺、甲氧苄氨嘧啶、琥珀磺胺噻唑等。

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